☰
 

SMILES:
C1CCCC[NH+]1C

Aroma Description:
ammonia, corn_chip, fishy, seafood, taco1

Receptor log10 EC50 Adj. Top Antagonist? Correlated Perceptual Qualities
TAAR8 -8 2 10 2  putrid
TAAR9 -5.7 2 10 2  (insufficient data)
TAAR5 -4 4 8.8 3, 1.85 4  ammonia
 

SMILES:
C1CCCC[NH+]1C

Aroma Description:
ammonia, corn_chip, fishy, seafood, taco

Receptor Dock Score Affinity A100 Correlated Perceptual Qualities

Dock Score: This is a measure of whether the algorithm thinks the odorant is an agonist of the receptor.
Affinity: The binding affinity, in kJ/mol, of the ligand docked in the active or inactive model, whichever is greater.
A100: A measure of the degree of activation of the receptor. See Ibrahim et al (2019).

1.) The Good Scents Company

2.) Qian Li Deorphanization of Olfactory Trace Amine-Associated Receptors Chapter in Methods in Molecular Biology ยท June 2018 DOI: 10.1007/978-1-4939-8609-5_2

3.) Liberles SD, Buck LB. A second class of chemosensory receptors in the olfactory epithelium. Nature. 2006 Aug 10;442(7103):645-50. doi: 10.1038/nature05066. Epub 2006 Jul 30. PMID: 16878137.

4.) Pacalon J, Belloir C, Fiorucci S, Briand L, Topin J. TAARs response to amine are largely affected by sequence variants. Submitted.