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Olfactory Receptor family 4 subfamily D member 1.

Sequence:

        10         20         30         40         50         60         70         80         90        100 
MEPQNTTQVS MFVLLGFSQT QELQKFLFLL FLLVYVTTIV GNLLIMVTVT FDCRLHTPMY FLLRNLALID LCYSTVTSPK MLVDFLHETK TISYQGCMAQ 

       110        120        130        140        150        160        170        180        190        200 
IFFFHLLGGG TVFFLSVMAY DRYIAISQPL RYVTIMNTQL CVGLVVAAWV GGFVHSIVQL ALILPLPFCG PNILDNFYCD VPQVLRLACT DTSLLEFLMI 

       210        220        230        240        250        260        270        280        290        300 
SNSGLLVIIW FLLLLISYTV ILVMLRSHSG KARRKAASTC TTHIIVVSMI FIPCIYIYTW PFTPFLMDKA VSISYTVMTP MLNPMIYTLR NQDMKAAMRR 

       310 
LGKCLVICRE

Transmembrane Helices:

  TMR1     TMR2     TMR3     TMR4     TMR5     TMR6     TMR7   

L E Q T        F  G Q Y S     I L   L S T D      I Y  M L F P  
 F K Q    D V L    A M C   A L Q V   F E L    I C P    A K D   
L L F L  M K P S  F F I Q   I S H   S I M L  I F I M  S I S V  
 L L F    T V T    L H F   V F G G   G S N    S V V    V T Y   
T V Y V  S Y C L  G G G L   V W A   I V L L  I I H T  M P T M  
 V I T    D I L    F V T   A V V L   F W I    T C T    P N L   
L L N G  A L N R  V S L F   G V C   L L L L  S A A K  T Y I M  
 V M I    L L F    Y A M   L Q T N   Y S I    R R A            
  T V T  Y M P T  I Y R D           L I V T  K G S H           
                   S I A             L M V                     
                        Q               S R                    
    

    UniProt | I-TASSER | AlphaFold | HORDE | GeneCards
Odorant EC50 Adjusted Top Antagonist? Aroma Notes
androstenone - 10 1  animal, musky
pi-23472 - 10 2  
furaneol - 0 1  sweet, cotton_candy, caramellic, strawberry, brown_sugar
alpha-ionone - 0 1  sweet, woody, floral, violet, orris, tropical, fruity
beta-ionone - 0 1  beeswax, berry, floral, fruity, sweet, tropical, woody, fragrant, sour, acid, vinegar, sharp, pungent
1-octen-3-one - 0 1  earthy, metallic, mushroom

1.) Hartmann C, Triller A, Spehr M, Dittrich R, Hatt H, Buettner A. Sperm-Activating Odorous Substances in Human Follicular Fluid and Vaginal Secretion: Identification by Gas Chromatography–Olfactometry and Ca2 Imaging. Chempluschem 78: 695–702, 2013. doi:10.1002/cplu.201300008

2.) Veitinger T, Riffell JR, Veitinger S, Nascimento JM, Triller A, Chandsawangbhuwana C, Schwane K, Geerts A, Wunder F, Berns MW, Neuhaus EM, Zimmer RK, Spehr M, Hatt H. Chemosensory Ca2+ dynamics correlate with diverse behavioral phenotypes in human sperm. J Biol Chem. 2011 May 13;286(19):17311-25. doi: 10.1074/jbc.M110.211524. Epub 2011 Mar 21. PMID: 21454470; PMCID: PMC3089573.