☰

Olfactory Receptor family 8 subfamily D member 2.

Sequence:

        10         20         30         40         50         60         70         80         90        100 
MATSNHSSGA EFILAGLTQR PELQLPLFLL FLGIYVVTVV GNLGMIFLIA LSSQLYPPVY YFLSHLSFID LCYSSVITPK MLVNFVPEEN IISFLECITQ 

       110        120        130        140        150        160        170        180        190        200 
LYFFLIFVIA EGYLLTAMEY DRYVAICRPL LYNIVMSHRV CSIMMAVVYS LGFLWATVHT TRMSVLSFCR SHTVSHYFCD ILPLLTLSCS STHINEILLF 

       210        220        230        240        250        260        270        280        290        300 
IIGGVNTLAT TLAVLISYAF IFSSILGIHS TEGQSKAFGT CSSHLLAVGI FFGSITFMYF KPPSSTTMEK EKVSSVFYIT IIPMLNPLIY SLRNKDVKNA 

       310        320 
LKKMTRGRQS S

Transmembrane Helices:

  TMR1     TMR2     TMR3     TMR4     TMR5     TMR6     TMR7   

L E P R      V F  E L F S     M R   I H T S  F Y M F  K E M T  
 P L Q    N V L    T I C   T T H V   I E N    T I S    V K E   
L L F L  M K P T  F Y L Q   T A W   I F L L  G F F I  F V S S  
 G L F    I V S    I L F   L F G L   G G I    G V A    T I Y   
V V Y I  S Y C L  A I V F   S Y V   L T N V  L L H S  M P I I  
 V V T    D I F    Y G E   V A M M   T T A    S C T    P N L   
G L N G  S L H S  A T L L   I S C   L V A L  G F A K  S Y I L  
 F I M    L F Y    Y E M   V R H S   Y S I    S Q G        L   
  A I L  Y V P P  V Y R D           F I F A  E T S H           
                   C I A             I S S                     
                        R               G L                    
    

    UniProt | I-TASSER | AlphaFold | HORDE | GeneCards
Odorant EC50 Adjusted Top Antagonist? Aroma Notes
muguet propanol - 4.0385 1  floral, lily_of_the_valley, woody
1-hexanol - 1.7308 1  alcoholic, ethereal, fruity, fusel, green, herbal, oily, pungent, sweet
caramel furanone - 0 2  burnt, caramellic, coffee, maple, sugar, sweet

1.) Ashti Baghaei, K. (2015). Large scale analysis of olfactory receptors with highly genetically variations in relation with specific anosmia (Doctoral dissertation, Bochum, Ruhr-Universität Bochum, Diss., 2013).

2.) Adipietro KA, Mainland JD, Matsunami H (2012) Functional Evolution of Mammalian Odorant Receptors. PLoS Genet 8(7): e1002821. doi:10.1371/ journal.pgen.1002821