Olfactory Receptor family 8 subfamily D member 2.
Estimated Expression: 46% of the population.
Expression estimate based on data from Verbeurgt et al (2014).
Sequence:
10 20 30 40 50 60 70 80 90 100 MATSNHSSGA EFILAGLTQR PELQLPLFLL FLGIYVVTVV GNLGMIFLIA LSSQLYPPVY YFLSHLSFID LCYSSVITPK MLVNFVPEEN IISFLECITQ 110 120 130 140 150 160 170 180 190 200 LYFFLIFVIA EGYLLTAMEY DRYVAICRPL LYNIVMSHRV CSIMMAVVYS LGFLWATVHT TRMSVLSFCR SHTVSHYFCD ILPLLTLSCS STHINEILLF 210 220 230 240 250 260 270 280 290 300 IIGGVNTLAT TLAVLISYAF IFSSILGIHS TEGQSKAFGT CSSHLLAVGI FFGSITFMYF KPPSSTTMEK EKVSSVFYIT IIPMLNPLIY SLRNKDVKNA 310 320 LKKMTRGRQS S
Transmembrane Helices:
TMR7 TMR6 TMR5 TMR4 TMR3 TMR2 TMR1 K E M T F Y M F I H T S M R I I N E V F L E P R V K E T I S I E N T T H V L F S N V L P L Q F V S S G F F I I F L L T A W T I C E M K P T L L F L T I Y G V A G G I L F G L Y L Q I V S G L F M P I I L L H S L T N V S Y V I L F F S Y C L V V Y I P N L S C T T T A V A M M I V F D I F V V T S Y I L G F A K L V A L I S C Y G E A S L H S G L N G S Q G Y S I V R H S T L L L F Y F I M E T S H F I F A Y E M A Y V P P L A I L I S S Y R D S I G L C I A V UniProt | I-TASSER | AlphaFold | HORDE | GeneCards | ORDB
| Odorant | EC50 | Adjusted Top | Antagonist? | Aroma Notes |
|---|---|---|---|---|
| muguet propanol | - | 4.0385 1 | floral, lily_of_the_valley, woody | |
| hexanol | - | 1.7308 1 | ethereal, fusel, oily, fruity, alcoholic, sweet, green, pungent, apple_skin | |
| sotolone | - | 0 2 | sweet, caramellic, maple, sugar, burnt_sugar, coffee, brown_sugar, cotton_candy |
1.) Ashti Baghaei, K. (2015). Large scale analysis of olfactory receptors with highly genetically variations in relation with specific anosmia (Doctoral dissertation, Bochum, Ruhr-Universität Bochum, Diss., 2013).
2.) Adipietro KA, Mainland JD, Matsunami H (2012) Functional Evolution of Mammalian Odorant Receptors. PLoS Genet 8(7): e1002821. doi:10.1371/ journal.pgen.1002821