SMILES:
[NH+](C)(C)C
Aroma Description:
ammonia, fishy, prawn1
SMILES:
[NH+](C)(C)C
Aroma Description:
ammonia, fishy, prawn
| Receptor | Dock Score | Affinity | A100 | Correlated Perceptual Qualities |
|---|
Dock Score: This is a measure of whether the algorithm thinks the odorant is an agonist of the receptor.
Affinity: The binding affinity, in kJ/mol, of the ligand docked in the active or inactive model, whichever is greater.
A100: A measure of the degree of activation of the receptor. See
Ibrahim et al (2019).
1.) The Good Scents Company
2.) Qian Li Deorphanization of Olfactory Trace Amine-Associated Receptors Chapter in Methods in Molecular Biology · June 2018 DOI: 10.1007/978-1-4939-8609-5_2
3.) Liberles SD, Buck LB. A second class of chemosensory receptors in the olfactory epithelium. Nature. 2006 Aug 10;442(7103):645-50. doi: 10.1038/nature05066. Epub 2006 Jul 30. PMID: 16878137.
4.) Wallrabenstein I, Singer M, Panten J, Hatt H, Gisselmann G. Timberol® Inhibits TAAR5-Mediated Responses to Trimethylamine and Influences the Olfactory Threshold in Humans. PLoS One. 2015;10(12):e0144704. Published 2015 Dec 18. doi:10.1371/journal.pone.0144704
5.) Pacalon J, Belloir C, Fiorucci S, Briand L, Topin J. TAARs response to amine are largely affected by sequence variants. Submitted.
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