methyl mercaptan
SMILES:
CS
Aroma Description:
alliaceous, cabbage, cheesy, creamy, eggy, garlic, meaty, oily, vegetable1
| Receptor | log10 EC50 | Adj. Top | Antagonist? | Correlated Perceptual Qualities |
|---|---|---|---|---|
| OR2M7 | - | 10 4 | eggy, cabbage, alliaceous, garlic | |
| OR2T11 | - | 3.913 5 | sulfurous, gassy, cabbage, skunk, onion | |
| OR2W1 | -3 2 | 1.5 2 | fatty, sweet, herbal, cucumber, orange, tart, mimosa, spicy, coumarinic, passionfruit | |
| OR2T1 | - | 2.6087 5 | eggy, sulfurous, cabbage, alliaceous, cheesy, creamy, sharp, garlic | |
| OR2T6 | - | 2.1739 5 | eggy, sulfurous, cabbage, alliaceous, garlic | |
| OR7D4 | - | 0.2 3 | animal |
methyl mercaptan
SMILES:
CS
Aroma Description:
alliaceous, cabbage, cheesy, creamy, eggy, garlic, meaty, oily, vegetable
| Receptor | Dock Score | Affinity | A100 | Correlated Perceptual Qualities |
|---|
Dock Score: This is a measure of whether the algorithm thinks the odorant is an agonist of the receptor.
Affinity: The binding affinity, in kJ/mol, of the ligand docked in the active or inactive model, whichever is greater.
A100: A measure of the degree of activation of the receptor. See
Ibrahim et al (2019).
1.) The Good Scents Company
2.) Block, Batista, Matsunami, Zhuang, Ahmed The role of metals in mammalian olfaction of low molecular weight organosulfur compound Nat. Prod. Rep., 2017,34, 529-557
3.) Keller A, Zhuang H, Chi Q, Vosshall LB, Matsunami H. Genetic variation in a human odorant receptor alters odour perception. Nature. 2007 Sep 27;449(7161):468-72. doi: 10.1038/nature06162. Epub 2007 Sep 16. PMID: 17873857.
4.) Pelchat ML, Bykowski C, Duke FF, Reed DR. Excretion and perception of a characteristic odor in urine after asparagus ingestion: a psychophysical and genetic study. Chem Senses. 2011;36(1):9-17. doi:10.1093/chemse/bjq081
5.) Antagonistic interactions between odorants alter human odor perception Yosuke Fukutani, Masashi Abe, Haruka Saito, Ryo Eguchi, Toshiaki Tazawa, Claire A. de March, Masafumi Yohda, Hiroaki Matsunami bioRxiv 2022.08.02.502184; doi: https://doi.org/10.1101/2022.08.02.502184