SMILES:
CCCCCCCCCCCCC=O
Aroma Description:
aldehydic, citrus, clean, fresh, grapefruit, peel, petal, soapy, waxy1
SMILES:
CCCCCCCCCCCCC=O
Aroma Description:
aldehydic, citrus, clean, fresh, grapefruit, peel, petal, soapy, waxy
| Receptor | Dock Score | Affinity | A100 | Correlated Perceptual Qualities |
|---|
Dock Score: This is a measure of whether the algorithm thinks the odorant is an agonist of the receptor.
Affinity: The binding affinity, in kJ/mol, of the ligand docked in the active or inactive model, whichever is greater.
A100: A measure of the degree of activation of the receptor. See
Ibrahim et al (2019).
1.) The Good Scents Company
2.) J. Topin, C.A. de March, L. Charlier, C. Ronin, S. Antonczak, J. Golebiowski, Discrimination between Olfactory Receptor Agonists and Non-agonists, Chem. Eur. J. 20 (2014) 10227-10230.
3.) Kalbe B, Osterloh M, Schulz VM, Altmüller J, Becker C, Osterloh S, Hatt H. OR2H2 regulates the differentiation of human myoblast cells by its ligand aldehyde 13-13. Arch Biochem Biophys. 2018 May 1;645:72-80. doi: 10.1016/j.abb.2018.03.017. Epub 2018 Mar 17. PMID: 29559321.
4.) Ji Min Kim, Sina Dziobaka, Ye Eun Yoon, et al. OR2H2 Activation Suppresses Cellular Senescence and Aging by Activating AMPK and Inducing Senolysis in VK2/E6E7 Cells, 23 September 2022, PREPRINT (Version 1) available at Research Square [https://doi.org/10.21203/rs.3.rs-2020909/v1]
5.) Weidinger, D., Jovancevic, N., Zwanziger, D., Theurer, S., Hönes, J., Führer, D., & Hatt, H. (2021). Functional characterisation of olfactory receptors in the thyroid gland. Frontiers in physiology, 12, 1158.