OR4S1

Olfactory Receptor family 4 subfamily S member 1.

Estimated Expression: 42% of the population.

Expression estimate based on data from Verbeurgt et al (2014).

Sequence:

        10         20         30         40         50         60         70         80         90        100 
MGAKNNVTEF VLFGLFESRE MQHTCFVVFF LFHVLTVLGN LLVIITINAR KTLKSPMYFF LSQLSFADIC YPSTTIPKMI ADTFVEHKII SFNGCMTQLF 

       110        120        130        140        150        160        170        180        190        200 
SAHFFGGTEI FLLTAMAYDR YVAICRPLHY TAIMDCRKCG LLAGASWLAG FLHSILQTLL TVQLPFCGPN EIDNFFCDVH PLLKLACADT YMVGLIVVAN 

       210        220        230        240        250        260        270        280        290        300 
SGMISLASFF ILIISYVIIL LNLRSQSSED RRKAVSTCGS HVITVLLVLM PPMFMYIRPS TTLAADKLII LFNIVMPPLL NPLIYTLRNN DVKNAMRKLF 

       310 
RVKRSLGEK

Transmembrane Helices:

  TMR7     TMR6     TMR5     TMR4     TMR3     TMR2     TMR1   


I L K D       T   M Y T D     T L   S I I K      F T  M E R S  
 F L I   T S P R   L G V   L T Q L   G N F    D A I    T H Q   
M V I N   I Y M   A V V I   I S H   Q T M C  M K P I  V V F C  
 L P P   F M P P   G S N   L F G A   S F L    T T S    L F F   
L P N L   M L V   L S I M   L W S   F F H A  P Y C I  L V H F  
 T Y I   L L V T   F S A   A G A L   T G G    D A F    L V T   
          I V H   I L I F   L G C   L F I E  S L Q S  L L N G  
         S G C T   Y S I   K R C D   A T L    L F F    I I V   
          S V A   L I I V           D Y A M  Y M P S  A N I T  
         K R R D   L N L             V Y R                 R   
                      S R           R C I A                    
    

    UniProt | I-TASSER | AlphaFold | HORDE | GeneCards | ORDB

Odorant	EC₅₀	Adjusted Top	Antagonist?	Aroma Notes
heptanal	-	0 ¹		aldehydic, cognac, fatty, fresh, green, herbal, ozone

1.) Lim J. H., J. Park, E. H. Oh, H. J. Ko, S. Hong, and Park, T. H. (2014) Nanovesicle-based bioelectronic nose for the diagnosis of lung cancer from human blood. Adv. Healthcare Mater., 3: 360–366.

Prot.	Sim.	Expr.	2.53	3.29	3.32	3.33	3.36	3.37	3.40	3.41	4.53	4.56	4.57	4.60	45.49	45.51	45.52	45.53	5.39	5.42	5.43	5.46	5.47	6.48	6.51	6.55	6.59	7.38	7.39	7.41	7.42
OR4S1	100	42%	Y	L	A	H	G	G	I	F	G	H	S	Q	F	D	V	H	V	N	S	I	S	L	P	Y	S	I	L	N	I
OR4F6	88		F	I	I	H	G	G	M	V	G	H	S	Q	F	D	L	P	V	N	S	I	S	F	L	Y	P	A	I	D	A
OR4F3	86	100%	A	I	I	H	G	G	M	V	G	H	S	Q	Y	D	L	P	V	N	S	I	C	F	P	Y	P	A	I	D	A
OR4F21	86	100%	A	I	I	H	G	G	M	V	G	H	S	Q	Y	D	L	P	V	N	S	I	C	F	P	Y	P	A	I	D	A
OR4F15	84	92%	F	I	S	H	G	G	M	V	G	H	S	Q	Y	D	L	P	V	N	S	I	S	F	L	Y	P	A	I	D	A
OR4C3	84	34%	Y	L	A	H	G	G	I	I	G	H	S	Q	A	D	L	Y	V	N	S	I	C	F	C	Y	P	A	L	Y	G
OR4X1	84	23%	Y	M	L	H	G	G	A	F	G	H	S	Q	F	D	V	H	I	N	G	I	S	F	C	Y	C	A	V	Y	T
OR4S2	83	57%	Y	L	V	H	G	C	I	F	G	H	S	Q	F	D	V	H	V	N	S	I	A	F	C	Y	D	A	V	Y	T
OR4M2	83	92%	Y	L	L	H	G	A	M	F	G	H	S	Q	F	D	I	T	M	S	S	I	S	F	S	Y	P	S	V	N	T
OR4B1	82	69%	Y	I	F	H	G	V	I	L	G	H	S	Q	F	D	L	Q	V	N	S	F	S	F	A	Y	P	A	V	Y	T
OR4P4	81	57%	Y	L	T	H	G	G	I	F	G	H	S	Q	F	D	V	Y	V	N	S	I	A	F	A	Y	V	A	L	Y	T
OR4X2	80	53%	Y	L	L	H	G	G	I	F	G	H	S	Q	F	D	L	V	I	N	G	L	S	F	C	S	S	A	V	Y	T
OR4C15	80	69%	F	L	E	H	A	G	V	I	G	H	S	Q	M	D	L	Y	V	N	S	I	C	F	C	Y	P	A	I	Y	I
OR4N5	80	96%	Y	L	L	H	G	A	M	F	G	H	S	Q	F	D	V	P	M	N	S	L	S	F	A	Y	F	S	L	H	T
OR4K17	80	84%	L	I	L	H	G	G	M	V	G	H	S	Q	F	D	L	P	I	N	S	I	S	F	C	Y	P	A	V	Y	T

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