☰

Olfactory Receptor family 4 subfamily P member 4.

Estimated Expression: 57% of the population.

Expression estimate based on data from Verbeurgt et al (2014).

Sequence:

        10         20         30         40         50         60         70         80         90        100 
MEKSNNSTLF ILLGFSQNKN IEVLCFVLFL FCYIAIWMGN LLIMISITCT QLIHQPMYFF LNYLSLSDLC YTSTVTPKLM VDLLAERKTI SYNNCMIQLF 

       110        120        130        140        150        160        170        180        190        200 
TTHFFGGIEI FILTGMAYDR YVAICKPLHY TIIMSRQKCN TIIIVCCTGG FIHSASQFLL TIFVPFCGPN EIDHYFCDVY PLLKLACSNI HMIGLLVIAN 

       210        220        230        240        250        260        270        280        290        300 
SGLIALVTFV VLLLSYVFIL YTIRAYSAER RSKALATCSS HVIVVVLFFA PALFIYIRPV TTFSEDKVFA LFYTIIAPMF NPLIYTLRNT EMKNAMRKVW 

       310        320 
CCQILLKRNQ LF

Transmembrane Helices:

  TMR7     TMR6     TMR5     TMR4     TMR3     TMR2     TMR1   


F V K D       T   M H I N     T L   S I T K      L L  I N K N  
 F L A   T V P R   L G I   L F Q S   N N Y    D V M    L V E   
I I T Y   I Y I   A I V L   A S H   Q I M C  L K P T  L V F C  
 M P A   F L A P   G S N   I F G G   T F L    V T S    F L F   
L P N F   A F F   L A I L   T C C   F F H T  T Y C L  A I Y C  
 T Y I   L V V V   F T V   V I I I   I G G    D S L    M W I   
          I V H   L L V V   T N C   I F I E  S L Y N  L L N G  
         S S C T   Y S L   K Q R S   G T L    L F F    I M I   
          A L A   L I F V           D Y A M  Y M P Q  C T I S  
         K S R R   I T Y             V Y R                 T   
                      A R           K C I A                    
    

    UniProt | I-TASSER | AlphaFold | HORDE | GeneCards | ORDB
Odorant EC50 Adjusted Top Antagonist? Aroma Notes
habanolide - 6.1538 1  animal, cloth, dry, laundered, metallic, musk, powdery, sweet, tropical, waxy
caproic acid - 1.9231 1  cheesy, fatty, sour, sweaty
civetone - 0.1923 1  clean, musk, dry, animal, sweet
exaltolide - 0.1923 1  animal, fruity, musk, natural, powdery
globanone - 0 1  animal, balsamic, cloth, dry, floral, laundered, musk, tobacco, waxy
heptanal - 0 2  aldehydic, cognac, fatty, fresh, green, herbal, ozone
muscone - 0 1  musk, animal, powdery

1.) Ashti Baghaei, K. (2015). Large scale analysis of olfactory receptors with highly genetically variations in relation with specific anosmia (Doctoral dissertation, Bochum, Ruhr-Universität Bochum, Diss., 2013).

2.) Lim J. H., J. Park, E. H. Oh, H. J. Ko, S. Hong, and Park, T. H. (2014) Nanovesicle-based bioelectronic nose for the diagnosis of lung cancer from human blood. Adv. Healthcare Mater., 3: 360–366.

 2.53 3.29 3.32 3.33 3.36 3.37 3.40 3.41 4.53 4.56 4.57 4.60 45.49 45.51 45.52 45.53 5.39 5.42 5.43 5.46 5.47 6.48 6.51 6.55 6.59 7.38 7.39 7.41 7.42
OR4P4Y L T H G G I F G H S Q F D V Y V N S I A F A Y V A L Y T
OR4C15F L E H A G V I G H S Q M D L Y V N S I C F C Y P A I Y I
OR4D1Y I F H G G V F G H S Q Y D V P M N S L V F C Y P S I Y T
OR4B1Y I F H G V I L G H S Q F D L Q V N S F S F A Y P A V Y T
OR4S2Y L V H G C I F G H S Q F D V H V N S I A F C Y D A V Y T
OR4A47Y L E H G G V F G H S Q F D M Y V N G A C F C Y P S V Y T
OR4C16L V S H G C I F S H S Q F D L Q L N S I C F C Y L A V Y T
OR10G8F L F H G G C F G H S Q L D A P I T V V A F G Y G A V Y T
OR4C46Y V E H G G G I G H A Q M D L N I N S I C F C Y P A I Y T
OR4F15F I S H G G M V G H S Q Y D L P V N S I S F L Y P A I D A
OR4C3Y L A H G G I I G H S Q A D L Y V N S I C F C Y P A L Y G
OR4K17L I L H G G M V G H S Q F D L P I N S I S F C Y P A V Y T
OR4A16Y L E H G G V F G H S Q V D M Y V N G I C F C Y P T V Y S
OR4C6F L E H G G I I G H A Q I D L F V N S M C F C Y P A V D S
OR4A5Y L D H G G V F G H S Q S D M H V N S I C F C Y P T V Y T
OR4F4L I L H G G M V G H S Q Y D L P V N S L T F C Y P A V Y S
OR4F5L I L H G G M V G H S Q Y D L P V N S L T F C Y P A V Y S
OR4F17L I L H G G M V G H S Q Y D L P V N S L T F C Y P A V Y S
OR4C12Y A E H G A I I G H A Q M D L Y V N S I C F C Y S A V Y T
OR4C13Y V E H R G V I G H A Q M D L Y I N S I C F C Y P A V Y T
OR4N5Y L L H G A M F G H S Q F D V P M N S L S F A Y F S L H T
OR10G7F L F H G S C F G H S Q F D A P I N I V A F G Y G A V Y T
OR4D5Y L F H G G I F G H S Q Y D V P M N N V T F C Y P S V Y T
OR4N2Y L L H G G G L G H S Q F D V P M N S M T F G Y P S L H T
OR4F3A I I H G G M V G H S Q Y D L P V N S I C F P Y P A I D A
OR4F21A I I H G G M V G H S Q Y D L P V N S I C F P Y P A I D A
OR4Q2Y L L H G A M F G H S Q F D V P M N S I S F C Y F S V Y N
OR4A15Y L D H A G V I G H S Q L D L Y M N G I C F C Y P T V L T
OR2C3F F S H G A C V G T S G F E M P M A S F V Y I Y A A L Y T
OR4D11F I F H G G I F G H S Q Y D V P M N N V T F C Y P S V F T
OR4D9F M F H G G V F G H S Q Y D V P M N N V S F C Y P S V F T
OR4F6F I I H G G M V G H S Q F D L P V N S I S F L Y P A I D A
OR4X1Y M L H G G A F G H S Q F D V H I N G I S F C Y C A V Y T
OR4L1L M M H G G M T G H S Q F D L P V D S L S F C Y P A V Y T
OR4C5S L E H G G I I G H A Q I D L F V N S M C F C Y P S V Y T
OR4D10F M F H G G V F G H S Q Y D V H M N N L T F C Y P S V F T
OR4Q3L I L H G A M F G H S Q Y D V P V N S L S F C Y F S L Y T
OR4K2L I L H T G I I G H S Q F D L P M T S I A F C Y P S V Y T
OR4K3L M L H G G I V G H A Q F D L P M T S I A F C Y P S V Y T
OR10G4F L F H G S C F G H S Q F D A P I D I V A F C Y G A I Y T
OR4N4Y L L H G G G L G H S Q F D V R M N S M T F A Y P S L H T
OR4E2H L L H A C I F G H S Q F D V P I N S I S F C Y P S V Y T
OR4K13L M M H G G M M G H S Q F D L P V D S L S F C Y P S V Y T
OR4K14L I L H G G M V G H S Q F D L P M D S L S F C Y P S V Y T
OR4K15V I V H T G M V G H T Q F D L P I D S L S F C Y P A V Y T
OR10G9F L F H G S C F G H S Q L D A P I D I V A F C Y G A I Y T
OR4M1Y L L H G A M F G H S Q F D I T M S S I S F S Y P S V H T
OR4S1Y L A H G G I F G H S Q F D V H V N S I S L P Y S I L N I
OR4C11F V L H G C I F S H S Q C D L Q L N S I C F C Y P A V Y T
OR4D6F I F H G G I F G H S Q Y Y V L M N N V T F C Y P S I N T
OR4M2Y L L H G A M F G H S Q F D I T M S S I S F S Y P S V N T
OR2G2F L S H G S C V G T T Q I E V P L A S F L Y I Y A S L Y T
OR4X2Y L L H G G I F G H S Q F D L V I N G L S F C S S A V Y T
×
 
 

Code version:
 

Docker used:
 

Files:
Active model: text 3D download
Inactive model: text 3D download
Active dock: text 3D download
Inactive dock: text 3D download
JSON entry: text   download