☰

Olfactory Receptor family 4 subfamily P member 4.

Sequence:

        10         20         30         40         50         60         70         80         90        100 
MEKSNNSTLF ILLGFSQNKN IEVLCFVLFL FCYIAIWMGN LLIMISITCT QLIHQPMYFF LNYLSLSDLC YTSTVTPKLM VDLLAERKTI SYNNCMIQLF 

       110        120        130        140        150        160        170        180        190        200 
TTHFFGGIEI FILTGMAYDR YVAICKPLHY TIIMSRQKCN TIIIVCCTGG FIHSASQFLL TIFVPFCGPN EIDHYFCDVY PLLKLACSNI HMIGLLVIAN 

       210        220        230        240        250        260        270        280        290        300 
SGLIALVTFV VLLLSYVFIL YTIRAYSAER RSKALATCSS HVIVVVLFFA PALFIYIRPV TTFSEDKVFA LFYTIIAPMF NPLIYTLRNT EMKNAMRKVW 

       310        320 
CCQILLKRNQ LF

Transmembrane Helices:

  TMR1     TMR2     TMR3     TMR4     TMR5     TMR6     TMR7   

I N K N      L L  N N Y S     T L   M H I N     P R   E S F T  
 L V E    D V M    I M C   L F Q S   L G I   I Y I F   V K D   
L V F C  L K P T  T F L Q   A S H   A I V L   L A P   F L A F  
 F L F    V T S    F H T   I F G G   G S N   A F F L   I T Y   
A I Y C  T Y C L  I G G F   T C C   L A I L   V V V   M P A I  
 M W I    D S L    F I E   V I I I   F T V   I V H S   P N F   
L L N G  S L Y N  G T L I   T N C   L L V V   S C T   T Y I L  
 I M I    L F F    Y A M   K Q R S   Y S L   A L A K           
  T I S  Y M P Q  V Y R D           L I F V   S R R            
                   C I A             I T Y   E A S Y           
                        K               A R                    
    

    UniProt | I-TASSER | AlphaFold | HORDE | GeneCards
Odorant EC50 Adjusted Top Antagonist? Aroma Notes
habanolide - 6.1538 1  animal, cloth, dry, laundered, metallic, musk, powdery, sweet, tropical, waxy
caproic acid - 1.9231 1  cheesy, fatty, sour, sweaty
civetone - 0.1923 1  animal, clean, dry, musk, sweet
pentadecalactone - 0.1923 1  animal, fruity, musk, natural, powdery
globanone - 0 1  animal, balsamic, cloth, dry, floral, laundered, musk, tobacco, waxy
heptanal - 0 2  aldehydic, cognac, fatty, fresh, green, herbal, ozone
muscone - 0 1  animal, fatty, musk, natural, powdery, sweet

1.) Ashti Baghaei, K. (2015). Large scale analysis of olfactory receptors with highly genetically variations in relation with specific anosmia (Doctoral dissertation, Bochum, Ruhr-Universität Bochum, Diss., 2013).

2.) Lim J. H., J. Park, E. H. Oh, H. J. Ko, S. Hong, and Park, T. H. (2014) Nanovesicle-based bioelectronic nose for the diagnosis of lung cancer from human blood. Adv. Healthcare Mater., 3: 360–366.