Olfactory Receptor family 51 subfamily S member 1.
Estimated Expression: 38% of the population.
Expression estimate based on data from Verbeurgt et al (2014).
Sequence:
10 20 30 40 50 60 70 80 90 100 MSTLPTQIAP NSSTSMAPTF LLVGMPGLSG APSWWTLPLI AVYLLSALGN GTILWIIALQ PALHRPMHFF LFLLSVSDIG LVTALMPTLL GIALAGAHTV 110 120 130 140 150 160 170 180 190 200 PASACLLQMV FIHVFSVMES SVLLAMSIDR ALAICRPLHY PALLTNGVIS KISLAISFRC LGLHLPLPFL LAYMPYCLPQ VLTHSYCLHP DVARLACPEA 210 220 230 240 250 260 270 280 290 300 WGAAYSLFVV LSAMGLDPLL IFFSYGLIGK VLQGVESRED RWKAGQTCAA HLSAVLLFYI PMILLALINH PELPITQHTH TLLSYVHFLL PPLINPILYS 310 320 330 VKMKEIRKRI LNRLQPRKVG GAQ
Transmembrane Helices:
TMR7 TMR6 TMR5 TMR4 TMR3 TMR2 TMR1 T H Q T I W A E P L L P V T H L A A G S L L T H L A L L A A G F P L P A S A I G L W S P V Y S L I M P F L S Y L H L Q L L C L T P M P L T W L F H I Y F L L V V G L C R F V M L A T A I L L P P L L V A G M A S F S I F V H I V L G I L L Y V P N I S L H A P D L A L S I M V S D S V L A S S Y L I A C T F I L L K S I V S S E S L L F T G N G V Q G A K Y S F V G N T A L L L F F W L I W R D G I L G D I S M H M P R L A I I E R S E L V K L A R Q V G Q C I A UniProt | I-TASSER | AlphaFold | HORDE | GeneCards | ORDB
| Odorant | EC50 | Adjusted Top | Antagonist? | Aroma Notes |
|---|---|---|---|---|
| geosmin | - | 3.75 1 | earthy, fresh, musty, soil | |
| delta-decalactone | - | 3.3333 2 | coconut, creamy, dairy, fatty, fresh, fruity, lactonic, milky, oily, peach, sweet | |
| butyric acid | - | 0.8333 2 | sharp, acetic, cheesy, buttery, fruity, dairy, creamy | |
| galbanum pyrazine | - | 0.375 1 | green_pea, bell_pepper, green, galbanum | |
| bean pyrazine | - | 0 1 | green_pea, earthy, beany, chocolate, nutty | |
| diacetyl | - | 0 2 | buttery, caramellic, creamy, pungent, sweet | |
| 2-methylisoborneol | - | 0 1 | earthy, musty | |
| 2,4,6-trichloroanisole | - | 0 1 | cork_taint |
1.) Son, M., D. G. Cho, J. H. Lim, J. Park, S. Hong, H. J. Ko, and Park, T. H. (2015) Real-time monitoring of geosmin and 2- methylisoborneol, representative odor compounds in water pollution using bioelectronic nose with human-like performance, Biosens. Bioelectron., 74: 199–206.
2.) Geithe, C.; Andersen, G.; Malki, A.; Krautwurst, D. A butter aroma recombinate activates human class-I odorant receptors. J. Agric. Food Chem. 2015, 63, 9410–9420.