☰

Olfactory Receptor family 6 subfamily Y member 1.

Estimated Expression: 92% of the population.

Expression estimate based on data from Verbeurgt et al (2014).

Sequence:

        10         20         30         40         50         60         70         80         90        100 
MTTIILEVDN HTVTTRFILL GFPTRPAFQL LFFSIFLATY LLTLLENLLI ILAIHSDGQL HKPMYFFLSH LSFLEMWYVT VISPKMLVDF LSHDKSISFN 

       110        120        130        140        150        160        170        180        190        200 
GCMTQLYFFV TFVCTEYILL AIMAFDRYVA ICNPLRYPVI MTNQLCGTLA GGCWFCGLMT AMIKMVFIAQ LHYCGMPQIN HYFCDISPLL NVSCEDASQA 

       210        220        230        240        250        260        270        280        290        300 
EMVDFFLALM VIAIPLCVVV ASYAAILATI LRIPSAQGRQ KAFSTCASHL TVVILFYSMT LFTYARPKLM YAYNSNKVVS VLYTVIVPLL NPIIYCLRNH 

       310        320        330 
EVKAALRKTI HCRGSGPQGN GAFSS

Transmembrane Helices:

  TMR7     TMR6     TMR5     TMR4     TMR3     TMR2     TMR1   


N S N Y  R A Y T  Q S A D     I F   S I S K      L F  F A P R  
 V V K    F L T    M E A   V M K I   G N F    D V L    L L Q   
Y L V S  M S Y F  F F D V   M A T   Q T M C  M K P S  I S F F  
 I V T    L I V    L A L   M L G C   F Y L    I V T    A L F   
L L P V  V T L H  A I V M   F W C   F T V F  V Y W M  L L Y T  
 I P N    S A C    L P I   G G A L   T C V    E L F    L L T   
L C Y I  T S F A  V V V C   T G C   L I Y E  S L H S  L L N E  
          K Q R    Y S A   L Q N T   I A L    L F F    L I I   
         G Q A S  L I A A           D F A M  Y M P K  S H I A  
                   I T A             V Y R                 D   
                    I R L           N C I A                    
    

    UniProt | I-TASSER | AlphaFold | HORDE | GeneCards | ORDB
Odorant EC50 Adjusted Top Antagonist? Aroma Notes
2-butanone - 0 1  acetone, ethereal, fruity, camphorous, chemical, green
diacetyl - 0 1  buttery, caramellic, creamy, pungent, sweet

1.) C. Trimmer, A. Keller, N. R. Murphy, L. L. Snyder, J. R. Willer, M. H. Nagai, N. Katsanis, L. B. Vosshall, H. Matsunami, and J. D. Mainland Genetic variation across the human olfactory receptor repertoire alters odor perception PNAS | May 7, 2019 | vol. 116 | no. 19 | 9475–9480
Prot.Sim.Expr.2.53 3.29 3.32 3.33 3.36 3.37 3.40 3.41 4.53 4.56 4.57 4.60 45.49 45.51 45.52 45.53 5.39 5.42 5.43 5.46 5.47 6.48 6.51 6.55 6.59 7.38 7.39 7.41 7.42
OR6Y1100 92%Y L F V V C Y I G T A K F D I S D L A V I Y T Y K S V Y T
OR6P193 65%Y L F I A C C V G S S K F D I S D L A M I Y T Y R S V Y T
OR10J488Y L Y L G V C F G T A Q F D I R T I S V L Y T Y K S V Y T
OR6A286 100%Y L F L G C C V G I S K F D V S D L A I L Y S Y K S V Y A
OR6B382 88%Y L F S V C C V G I S K F D I S D L A I L Y L Y Q S V Y T
OR6B282 92%Y L F S V C C V G I S K F D I S D L A I L Y L Y Q S A Y T
OR6B182 100%Y L F I M C C V G I S K F D I S D L A I F Y I Y R S I Y A
OR2V182L I F V V G G L G D G Q F E V Q L C C M L Y A Y R S I Y T
OR10J181 80%Y M F V G I C F G V A Q F D I R T I S V L Y A Y K S V Y T
OR10J381 26%Y L Y L G I C F G M A Q F D V R N V S V L Y A Y K S V Y T
OR5A181 100%Y F F V G L C L G S S Q F D L P N V V V G F A Y S S V Y S
OR8I280 30%Y M F V V C C F G S S S F D T T S L A T L Y L Y D S V Y T
OR7A1780 100%F M F V G G S L A N S Q F E L N M A A L A C G Y S S V Y T
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