SMILES:
CC(CCC=C(C)C)CC=O
Aroma Description:
sweet, dry, floral, herbal, waxy, aldehydic, citrus1
| Receptor | Expression | log10 EC50 | Adj. Top | Antagonist? | Correlated Perceptual Qualities |
|---|---|---|---|---|---|
| OR52D1 | 100 | - | 1.1168 2 | dairy, cheesy, anise, milky, creamy, sour, sharp, peach, lactonic, rancid | |
| OR51B4 | 100 | - | 0 3 | ||
| OR2W1 | 53 | - | -0.1626 6 | ||
| OR5K1 | 100 | - | -0.1626 6 | ||
| OR5P3 | 100 | - | -0.1626 6 | ||
| OR4M1 | ? | - | -0.25 4 | ||
| OR2L13 | 88 | - | -0.6 7 | ||
| OR51E1 | 100 | - | -0.9091 5 |
SMILES:
CC(CCC=C(C)C)CC=O
Aroma Description:
sweet, dry, floral, herbal, waxy, aldehydic, citrus
| Receptor | Expr.% | Agonist? | Dock Score | Known agonist | Correlated Perceptual Qualities |
|---|
Dock Score is a measure of how strongly the algorithm thinks the odorant is likely to be an agonist of the receptor.
Receptors in italics are "orphans", i.e. receptors whose agonists have not been identified experimentally.
1.) The Good Scents Company
2.) Guenhael Sanz, Claire Schlegel, Jean-Claude Pernollet and Loic Briand Comparison of Odorant Specificity of Two Human Olfactory Receptors from Different Phylogenetic Classes and Evidence for Antagonism Chemical Senses vol. 30 no. 1 (2005) doi:10.1093/chemse/bji002
3.) Weber, Lea et al. “Activation of odorant receptor in colorectal cancer cells leads to inhibition of cell proliferation and apoptosis.” PloS one vol. 12,3 e0172491. 8 Mar. 2017, doi:10.1371/journal.pone.0172491
4.) Zhao W, Ho L, Varghese M, Yemul S, Dams-O'Connor K, Gordon W, Knable L, Freire D, Haroutunian V, Pasinetti GM. Decreased level of olfactory receptors in blood cells following traumatic brain injury and potential association with tauopathy. J Alzheimers Dis. 2013;34(2):417-429. doi: 10.3233/JAD-121894. PMID: 23241557; PMCID: PMC3968322.
5.) Aya Kato, Naoko Saito, Etsuji Wakisaka (2016) Method for searching for malodor control agent, malodor control agent, and malodor control method. US9526680B2
6.) Aya Kato, Naoko Saito (2015) Odor control agent. JP5798382B2
7.) Morrell CN, Mix D, Aggarwal A, Bhandari R, Godwin M, Owens P 3rd, Lyden SP, Doyle A, Krauel K, Rondina MT, Mohan A, Lowenstein CJ, Shim S, Stauffer S, Josyula VP, Ture SK, Yule DI, Wagner LE 3rd, Ashton JM, Elbadawi A, Cameron SJ. Platelet olfactory receptor activation limits platelet reactivity and growth of aortic aneurysms. J Clin Invest. 2022 May 2;132(9):e152373. doi: 10.1172/JCI152373. PMID: 35324479; PMCID: PMC9057618.