SMILES:
CCCCCCCCCCC=O
Aroma Description:
aldehydic, citrus, cloth, fatty, floral, green, laundered, soapy, waxy1
| Receptor | Expression | log10 EC50 | Adj. Top | Antagonist? | Correlated Perceptual Qualities |
|---|---|---|---|---|---|
| OR56A4 | 100 | -7 2 | - | cloth, laundered, cheesy, waxy, fatty, orange_peel, creamy, dairy, coconut | |
| OR2T4 | 80 | -5.7 3 | 10 3 | alliaceous, green_onion, onion, eggy, garlic | |
| VN1R5 | ? | - | 8 7 | tart, orange_peel, aldehydic, spearmint, caraway, waxy, peely, citrus, blueberry, rose | |
| OR1G1 | 61 | - | 3.2995 4 | sweet, waxy, citrus, fresh, tart, orange, aldehydic, floral, rose, fatty | |
| OR2L13 | 88 | - | 2.8571 3 | cilantro, spearmint, greasy, soapy, honey, watery | |
| OR52D1 | 100 | - | 2.132 4 | dairy, cheesy, anise, milky, creamy, sour, sharp, peach, lactonic, rancid | |
| OR7D4 | 96 | - | 0.1 5 | animal, citrus, orange, peely, tart, aldehydic, blueberry | |
| OR1D2 | 100 | - | 0 6 | Y |
SMILES:
CCCCCCCCCCC=O
Aroma Description:
aldehydic, citrus, cloth, fatty, floral, green, laundered, soapy, waxy
| Receptor | Expr.% | Agonist? | Dock Score | Known agonist | Correlated Perceptual Qualities |
|---|
Dock Score is a measure of how strongly the algorithm thinks the odorant is likely to be an agonist of the receptor.
Receptors in italics are "orphans", i.e. receptors whose agonists have not been identified experimentally.
1.) The Good Scents Company
2.) Mainland JD, Li YR, Zhou T, Liu WL, Matsunami H. Human olfactory receptor responses to odorants. Sci Data. 2015 Feb 3;2:150002. doi: 10.1038/sdata.2015.2. PMID: 25977809; PMCID: PMC4412152.
3.) Emily A. Yasi, Sara L. Eisen, Hanfei Wang, Widianti Sugianto, Anita R. Minniefield, Kaitlyn A. Hoover, Paul J. Branham, and Pamela Peralta-Yahya Rapid Deorphanization of Human Olfactory Receptors in Yeast Biochemistry 2019, 58, 2160-2166
4.) Guenhael Sanz, Claire Schlegel, Jean-Claude Pernollet and Loic Briand Comparison of Odorant Specificity of Two Human Olfactory Receptors from Different Phylogenetic Classes and Evidence for Antagonism Chemical Senses vol. 30 no. 1 (2005) doi:10.1093/chemse/bji002
5.) Keller A, Zhuang H, Chi Q, Vosshall LB, Matsunami H. Genetic variation in a human odorant receptor alters odour perception. Nature. 2007 Sep 27;449(7161):468-72. doi: 10.1038/nature06162. Epub 2007 Sep 16. PMID: 17873857.
6.) B.L. Cook, D. Steuerwald, L. Kaiser, J. Graveland-Bikker, M. Vanberghem, A.P. Berke, K. Herlihy, H. Pick, H. Vogel, S. Zhang, Large-scale production and study of a synthetic G protein-coupled receptor: Human olfactory receptor 17-4, Proc. Natl. Acad. Sci. USA 106 (2009) 11925-11930
7.) Krautwurst D. Human olfactory receptor families and their odorants. Chem Biodivers. 2008 Jun;5(6):842-52. doi: 10.1002/cbdv.200890099. PMID: 18618407.