Olfactory Receptor family 2 subfamily T member 4.
Estimated Expression: 80% of the population.
Expression estimate based on data from Verbeurgt et al (2014).
Sequence:
10 20 30 40 50 60 70 80 90 100 MDNITWMASH TGWSDFILMG LFRQSKHPMA NITWMANHTG WSDFILLGLF RQSKHPALLC VVIFVVFLMA LSGNAVLILL IHCDAHLHTP MYFFISQLSL 110 120 130 140 150 160 170 180 190 200 MDMAYISVTV PKMLLDQVMG VNKISAPECG MQMFFYVTLA GSEFFLLATM AYDRYVAICH PLRYPVLMNH RVCLFLSSGC WFLGSVDGFT FTPITMTFPF 210 220 230 240 250 260 270 280 290 300 RGSREIHHFF CEVPAVLNLS CSDTSLYEIF MYLCCVLMLL IPVVIISSSY LLILLTIHGM NSAEGRKKAF ATCSSHLTVV ILFYGAAIYT YMLPSSYHTP 310 320 330 340 350 EKDMMVSVFY TILTPVVNPL IYSLRNKDVM GALKKMLTVE PAFQKAME
Transmembrane Helices:
TMR7 TMR6 TMR5 TMR4 TMR3 TMR2 TMR1 D K E P Y L S T D T I S I K N V Q H K S Q V M M S S P L I E Y P T F T E P A D L L L A P Y F V S M Y T L Y M F F G D Q M G C M K P V V V C L L I T Y I A A V C C V S G L F F M T V S V F I V V P T G Y F L L M L F W C L T V Y I Y A M M L F V L P N L I V V V P I G S S L S G A D M L S L A Y I T L H S I I V F L C L F F E S L Q S V A N G S S C T Y S S V R H N T A L I F F L I L A F A L I L L D Y A M Y M P T C H I L K K R G I T L V Y R D M G H H C I A UniProt | I-TASSER | AlphaFold | HORDE | GeneCards | ORDB
1.) Roger EmterAndreas Natsch Modified olfactory receptors WO2024126820A1
2.) Emily A. Yasi, Sara L. Eisen, Hanfei Wang, Widianti Sugianto, Anita R. Minniefield, Kaitlyn A. Hoover, Paul J. Branham, and Pamela Peralta-Yahya Rapid Deorphanization of Human Olfactory Receptors in Yeast Biochemistry 2019, 58, 2160-2166
3.) Lim J. H., J. Park, E. H. Oh, H. J. Ko, S. Hong, and Park, T. H. (2014) Nanovesicle-based bioelectronic nose for the diagnosis of lung cancer from human blood. Adv. Healthcare Mater., 3: 360–366.
| Prot. | Sim. | Expr. | 2.53 | 3.29 | 3.32 | 3.33 | 3.36 | 3.37 | 3.40 | 3.41 | 4.53 | 4.56 | 4.57 | 4.60 | 45.49 | 45.51 | 45.52 | 45.53 | 5.39 | 5.42 | 5.43 | 5.46 | 5.47 | 6.48 | 6.51 | 6.55 | 6.59 | 7.38 | 7.39 | 7.41 | 7.42 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| OR2T4 | 100 | 80% | Y | M | Y | V | A | G | F | F | G | D | G | F | F | E | V | P | M | C | C | M | L | Y | A | Y | S | S | V | Y | T |
| OR2T5 | 98 | 100% | Y | M | Y | L | A | G | F | F | G | D | G | L | F | E | V | P | M | C | C | M | L | Y | A | Y | S | S | V | Y | T |
| OR2T29 | 98 | 100% | Y | M | Y | L | A | G | F | F | G | D | G | L | F | E | V | P | M | C | C | M | L | Y | A | Y | S | S | V | Y | T |
| OR2T11 | 97 | 96% | F | I | Y | L | I | G | F | F | G | D | G | L | F | E | I | P | M | C | C | M | L | Y | A | Y | Q | S | A | Y | T |
| OR2T6 | 93 | 92% | Y | C | Y | M | M | G | F | F | G | D | S | L | F | E | A | P | M | C | C | M | L | Y | A | Y | Q | S | A | Y | T |
| OR2T2 | 92 | Y | I | Y | L | I | G | F | F | G | D | G | L | F | E | I | P | M | C | C | M | L | Y | A | N | H | S | A | Y | T | |
| OR2T35 | 91 | Y | I | L | L | I | G | F | F | G | D | G | L | F | E | I | P | M | C | C | M | L | Y | A | N | H | S | A | Y | T | |
| OR2T27 | 91 | 96% | Y | H | Y | L | A | G | F | F | G | D | G | L | F | E | V | P | M | C | C | M | L | Y | A | Y | H | S | A | Y | T |
| OR2T1 | 91 | 69% | Y | H | Y | L | V | G | F | F | G | D | G | L | F | E | A | P | M | C | C | M | L | Y | A | Y | H | S | V | Y | T |
| OR2V2 | 90 | 96% | L | I | F | V | V | G | G | L | G | D | G | Q | F | E | M | L | I | C | C | M | L | Y | A | Y | R | S | I | Y | T |
| OR2T10 | 90 | 92% | Y | M | Y | L | G | G | C | C | G | D | G | L | F | E | V | P | M | C | C | M | L | Y | A | Y | S | S | F | Y | T |
| OR2T3 | 90 | Y | M | Y | L | A | G | V | F | G | D | G | L | F | E | T | P | M | C | C | M | L | F | S | Y | S | S | A | Y | T | |
| OR2M4 | 89 | 96% | L | I | Y | V | L | G | C | F | G | D | G | V | F | D | V | A | L | C | C | M | L | Y | A | Y | A | S | A | Y | T |
| OR2M5 | 89 | 34% | L | I | Y | V | L | G | C | F | G | D | A | D | F | D | F | P | L | C | C | M | I | Y | G | Y | T | S | V | Y | T |
| OR11L1 | 89 | 100% | Y | L | F | V | G | A | C | F | G | T | G | P | F | D | L | P | I | L | S | V | L | Y | M | Y | S | S | V | Y | T |
| OR2T12 | 88 | 69% | L | I | L | P | G | G | C | F | G | D | G | Q | F | E | A | P | M | C | C | M | L | Y | G | Y | K | S | A | Y | T |
| OR2V1 | 87 | L | I | F | V | V | G | G | L | G | D | G | Q | F | E | V | Q | L | C | C | M | L | Y | A | Y | R | S | I | Y | T | |
| OR2M2 | 86 | 100% | L | I | Y | I | S | G | C | F | G | D | G | D | F | E | F | P | I | C | C | M | L | Y | A | Y | T | S | V | Y | T |
| OR2AG1 | 86 | 100% | F | M | A | L | G | G | D | L | A | S | A | Y | L | E | I | P | V | M | G | F | L | Y | A | Y | S | S | V | Y | T |
| OR2M3 | 86 | 100% | L | I | Y | T | L | G | C | F | G | D | G | D | F | D | F | P | L | C | C | M | I | Y | A | Y | T | S | V | Y | T |
| OR10K2 | 86 | 96% | Y | M | F | L | G | C | S | F | G | V | A | I | F | D | I | A | I | L | C | V | L | Y | A | Y | Q | S | V | Y | T |
| OR2T8 | 85 | 96% | L | I | L | P | G | G | C | F | G | D | G | Q | F | E | T | P | M | C | C | M | L | Y | A | Y | K | S | A | Y | T |
| OR2T33 | 85 | 92% | L | I | L | P | G | G | C | F | G | D | G | Q | F | E | T | P | M | C | C | M | L | Y | A | Y | K | S | A | Y | T |
| OR2T34 | 85 | Y | M | H | L | A | G | V | F | G | D | G | L | F | E | T | P | T | C | C | M | L | F | S | Y | S | S | A | Y | T | |
| OR2M7 | 84 | 34% | L | I | Y | I | L | G | C | F | G | D | G | D | C | D | F | P | I | C | C | M | L | Y | G | C | T | S | V | Y | T |
| OR8J3 | 84 | 96% | N | L | F | L | I | V | V | M | G | T | A | V | Y | D | I | A | V | S | A | N | L | Y | M | Y | Q | S | V | Y | T |
| OR7G3 | 83 | F | I | V | L | V | G | N | G | S | D | A | H | F | E | L | A | V | V | T | L | G | Y | G | Y | S | S | V | Y | T | |
| OR10AD1 | 83 | 100% | F | M | V | F | G | V | C | I | G | N | G | L | F | E | A | P | I | D | A | V | I | Y | A | Y | H | S | L | Y | T |
| OR5AR1 | 82 | 53% | Y | F | F | V | V | D | C | Y | G | S | L | H | F | E | I | P | L | L | C | I | E | Y | V | Y | T | S | V | Y | T |
| OR10P1 | 82 | 80% | Y | M | F | I | G | I | C | C | G | T | A | H | L | D | I | L | V | A | T | F | I | F | A | Y | Q | S | L | Y | T |
| OR5AP2 | 82 | 61% | Y | F | F | G | L | G | C | F | G | N | A | H | Y | D | T | P | I | F | S | I | V | F | I | Y | T | S | V | Y | T |
| OR6C2 | 82 | 100% | F | I | V | I | G | A | F | F | G | I | I | P | S | D | A | G | V | M | A | A | L | Y | C | Y | S | S | V | T | T |
| OR5V1 | 81 | 96% | Y | L | F | V | V | G | C | L | G | N | S | H | F | D | I | P | L | T | G | I | G | Y | A | Y | I | S | V | Y | S |
| OR8G1 | 81 | 88% | H | L | F | L | A | I | C | H | G | C | A | H | F | D | L | L | I | V | G | N | I | F | A | Y | S | S | V | Y | T |
| OR14C36 | 81 | 84% | Y | V | V | V | V | Y | L | L | G | Y | A | H | F | D | I | P | I | S | A | V | G | L | C | Y | P | S | G | Y | S |
| OR2L8 | 81 | 100% | Y | S | F | L | G | G | A | L | G | N | A | H | F | D | V | P | V | S | A | F | L | Y | F | Y | R | A | V | Y | T |
| OR2Z1 | 81 | 84% | C | I | L | T | G | V | G | V | G | N | A | Q | F | E | V | P | L | S | G | I | L | Y | A | Y | C | S | L | Y | S |
| OR5B21 | 81 | 100% | Y | F | F | V | A | T | C | Y | G | N | A | H | F | D | I | P | V | V | A | N | V | Y | I | Y | N | S | V | Y | T |
| OR5C1 | 80 | 100% | Y | M | F | A | A | D | C | C | G | S | A | H | F | D | I | P | L | I | C | I | Q | Y | L | Y | S | S | V | Y | T |
| OR5P3 | 80 | 100% | Y | L | V | V | G | T | C | F | G | N | A | F | F | D | Y | S | P | S | S | I | I | Y | I | Y | K | S | V | Y | T |
| OR5P2 | 80 | 100% | Y | L | A | A | A | T | C | V | G | I | A | Y | F | D | F | A | L | S | S | I | I | Y | I | Y | N | S | V | Y | T |
| OR10R2 | 80 | 57% | Y | M | F | L | A | I | C | L | G | A | S | V | F | D | I | S | I | C | G | V | L | Y | A | Y | T | T | V | Y | T |
| OR14J1 | 80 | 88% | F | V | F | I | A | S | V | A | G | S | G | H | F | D | V | P | L | F | T | A | A | L | A | F | P | S | V | Y | T |
| OR8D1 | 80 | 96% | Y | L | F | V | V | V | G | Y | G | S | A | H | F | D | V | L | L | I | A | N | T | F | I | Y | P | S | V | Y | T |
| OR8D4 | 80 | 96% | Y | L | F | C | V | I | C | Y | G | D | A | H | F | D | I | V | I | I | G | N | M | Y | L | Y | A | S | V | Y | T |
| OR8J1 | 80 | 73% | N | L | F | L | I | V | V | I | G | T | A | V | Y | D | N | V | V | S | A | N | V | Y | L | Y | R | S | V | Y | T |