Olfactory Receptor family 1 subfamily A member 2.

Estimated Expression: 19% of the population.

Expression estimate based on data from Verbeurgt et al (2014).

Sequence:

        10         20         30         40         50         60         70         80         90        100 
MKKENQSFNL DFILLGVTSQ QEQNNVFFVI FLCIYPITLT GNLLIILAIC ADIRLHNPMY FLLANLSLVD IIFSSVTIPK VLANHLLGSK FISFGGCLMQ 

       110        120        130        140        150        160        170        180        190        200 
MYFMIALAKA DSYTLAAMAY DRAVAISCPL HYTTIMSPRS CILLIAGSWV IGNTSALPHT LLTASLSFCG NQEVANFYCD IMPLLKLSCS DVHFNVKMMY 

       210        220        230        240        250        260        270        280        290        300 
LGVGVFSLPL LCIIVSYVQV FSTVFQVPST KSLFKAFCTC GSHLTVVFLY YGTTMGMYFR PLTSYSPKDA VITVMYVAVT PALNPFIYSL RNWDMKAALQ 

       310 
KLFSKRISS

    

Transmembrane Helices:

  TMR7     TMR6     TMR5     TMR4     TMR3     TMR2     TMR1   

V A D K       T   H V D S     T L   I F K S      L H  Q E Q Q  
 V T I   L P R F   V N F   L T H P   G F S    N A L    V N N   
A V Y M   Y M G   Y M M K   L A S   M L C G  V K P I  I V F F  
 P T V   M T T G   V G L   T N G I   Y M Q    T V S    C L F   
P N L A   Y Y L   S F V G   V W S   A I M F  S F I I  I P Y I  
 Y I F   F V V T   L P L   G A I L   K A L    D V L    T L T   
      S   L H S   I I C L   L I C   Y S D A  S L N A  L L N G  
         G C T C   Y S V   S R P S   A L T    L L F    L I I   
          F A K   F V Q V           Y A M A  Y M P N  A C I A  
         F L S K   V T S             A R D                 D   
                      Q F           S I A V                    
    

    UniProt | I-TASSER | AlphaFold | HORDE | GeneCards | ORDB
Odorant EC50 Adjusted Top Antagonist? Aroma Notes
nerolidol - 9 1  floral, green, waxy, citrus, woody, fruity, melon
geraniol -8 1 4.5 1  citrus, floral, fruity, rose, sweet, waxy
helional -6.47 2 6 2  cyclamen, fresh, green, hay, ozone, watery
heptanal -6.77 3 4 3  aldehydic, cognac, fatty, fresh, green, herbal, ozone
nonanal -4.89 1 7 1  waxy, aldehydic, rose, fresh, orris, orange_peel, fatty, peely
4-decenal -5.78 1 5 1  aldehydic, citrus, fatty, fresh, green, mandarin, orange, tangerine
octanal -6.37 1 4 1  aldehydic, citrus, fatty, green, orange, peel, waxy
l-limonene - 7 1  terpenic, pine, herbal, peppery
(S)-(-)-citronellal -6.62 2 (agonist) 2  citrus, clean, herbal
hydroxycitronellal -6.41 1 (agonist) 1  floral, green, lily, melon, sweet, tropical, waxy
decanal - 5.5 1  sweet, aldehydic, waxy, orange_peel, citrus, floral
citral -5.83 1 (agonist) 1  sharp, lemon, sweet, fresh, juicy, lemon_peel, tart, green, citrus, lime, woody, herbal
(-)-carveol -5.78 1 (agonist) 1  minty, spearmint, cooling, green, herbal, caraway, spicy, weedy, plastic, earthy, mahogany
(R)-(+)-citronellal - 5 1  citrus, fresh, herbal
(E),(E)-2,4-decadienal - 5 4  oily, cucumber, melon, citrus, pumpkin, nutty, fatty, chicken, fried, chicken_fat, coriander, brothy
nerol - 5 1  citrus, floral, fresh, green, lemon, lime, magnolia, natural, neroli, spicy, sweet, waxy
trimethylamine - 5 1  ammonia, fishy, prawn
1-octanol -5.22 1 (agonist) 1  aldehydic, green, mushroom, orange, rose, waxy
(R)-(+)-citronellol -5.09 1 (agonist) 1  citronella, floral, leafy, oily, petal, rose
alpha-ionone - 4 1  sweet, woody, floral, violet, orris, tropical, fruity
1-octen-3-one - 4 1  earthy, metallic, mushroom
(R)-(-)-carvone - 0 5  herbal, minty, spearmint, sweet
(S)-(+)-carvone - 0 5  bready, caraway, minty, spicy
citralva - 0 1  aldehydic, citrus, lemon, metallic
citronellic acid - 0 1  green, grassy, smoky, fatty, floral, waxy, citronella, vegetable, tobacco
(S)-(-)-citronellol - 0 4  citrus, fatty, floral, fruity, green, leathery, rose, sweet, terpenic, waxy
hexanal - 0 4  aldehydic, fatty, fresh, fruity, grass, green, leafy, sweaty
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