Olfactory Receptor family 51 subfamily I member 2.
Sequence:
10 20 30 40 50 60 70 80 90 100 MGLFNVTHPA FFLLTGIPGL ESSHSWLSGP LCVMYAVALG GNTVILQAVR VEPSLHEPMY YFLSMLSFSD VAISMATLPT VLRTFCLNAR NITFDACLIQ 110 120 130 140 150 160 170 180 190 200 MFLIHFFSMM ESGILLAMSF DRYVAICDPL RYATVLTTEV IAAMGLGAAA RSFITLFPLP FLIKRLPICR SNVLSHSYCL HPDMMRLACA DISINSIYGL 210 220 230 240 250 260 270 280 290 300 FVLVSTFGMD LFFIFLSYVL ILRSVMATAS REERLKALNT CVSHILAVLA FYVPMIGVST VHRFGKHVPC YIHVLMSNVY LFVPPVLNPL IYSAKTKEIR 310 320 RAIFRMFHHI KI
Transmembrane Helices:
TMR1 TMR2 TMR3 TMR4 TMR5 TMR6 TMR7 S E L G C F A D F T L I S I D V I Y C P S H S T R L I L C F P L P I S N T S V G L V H G S L W V T P L L F M Q F L T F L G Y I M P V N S M C L P T A M F H I I F S R V L V V Y F A F L Y A Y M V S I A V M M S F A A A G F T S L V A V P P V L A V D S F G S E G L G M L D M L I H S P N L T N G G S L M S A L L I A A I F I F F V C T S Y I L L I V L F Y F S M V E T T Y S L N L A K K A R V A Q Y M P E V Y R D L I L V L R E C I A V S R E R S A D A M UniProt | I-TASSER | AlphaFold | HORDE | GeneCards
| Odorant | EC50 | Adjusted Top | Antagonist? | Aroma Notes |
|---|---|---|---|---|
| isovaleric acid | -4.4 1 | 9.0909 1 | cheesy, sour, sweaty, tropical | |
| 3-methyl-2-hexenoic acid | -4.52 2 | 5 2 | cheesy, fruity | |
| caproic acid | -4.4 1 | 4.4545 1 | cheesy, fatty, sour, sweaty | |
| delta-decalactone | - | 2.5 3 | coconut, creamy, dairy, fatty, fresh, fruity, lactonic, milky, oily, peach, sweet | |
| butyric acid | - | 0.4167 3 | acetic, buttery, cheesy, fruity, sharp | |
| diacetyl | - | 0 3 | buttery, caramellic, creamy, pungent, sweet | |
| cuminaldehyde | - | -0.9091 1 | cumin, green, herbal, spicy | |
| cyclamal | - | -0.9091 1 | cyclamen, floral, fresh, green, musty, rhubarb | |
| hydroxycitronellal | - | -0.9091 1 | floral, green, lily, melon, sweet, tropical, waxy | |
| lilial | - | -0.9091 1 | cumin, floral, green, muguet, powdery, watery | |
| bourgeonal | - | -1.8182 1 | cyclamen, floral, fresh, sweet, watery | |
| florhydral | - | -1.8182 1 | floral, green, muguet, linden_flower, lily_of_the_valley, fresh |
1.) Aya Kato, Naoko Saito, Etsuji Wakisaka (2016) Method for searching for malodor control agent, malodor control agent, and malodor control method. US9526680B2
2.) Aya Kato, Naoko Saito (2018) Search method for odor control agent JP6422665B2
3.) Geithe, C.; Andersen, G.; Malki, A.; Krautwurst, D. A butter aroma recombinate activates human class-I odorant receptors. J. Agric. Food Chem. 2015, 63, 9410–9420.