☰

Olfactory Receptor family 5 subfamily AC member 2.

Sequence:

        10         20         30         40         50         60         70         80         90        100 
MDISEGNKTL VTEFVLTGLT DRPWLHVLFF VVFLVVYLIT MVGNLGLIVL IWNDPHLHMP MYLFLGGLAF SDACTSTSIT PRMLVNFLDK TAMISLAECI 

       110        120        130        140        150        160        170        180        190        200 
TQFYFFASSA TTECFLLVMM AYDRYVAICN PLLYPVMMSN KLSAQLLSIS YVIGFLHPLV HVSLLLRLTF CRFNIIHYFY CEILQLFKIS CNGPSINALM 

       210        220        230        240        250        260        270        280        290        300 
IFIFGAFIQI PTLMTIIISY TRVLFDILKK KSEKGRSKAF STCGAHLLSV SLYYGTLIFM YVRPASGLAE DQDKVYSLFY TIIIPLLNPF IYSLRNKKVM 

       310 
HALRRVIRK

Transmembrane Helices:

  TMR1     TMR2     TMR3     TMR4     TMR5     TMR6     TMR7   

L W P R        F  E A L S     L L   I S P G       R   Q D E A  
 L V H    N V L    T I C   S V H V   L A N   V Y M F   V K D   
V V F F  M R P T  F Y F Q   L P H   I F I M   I L T   F L S Y  
 V L F    I S T    S A F   L F G I   A G F   G Y Y L   I T Y   
I L Y V  S T C A  T T A S   V Y S   I Q I F   S V S   L P I I  
 V M T    D S F    F C E   I S L L   L T P   L L H A   P N L   
G L N G  A L G G  M V L L   Q A S   I I T M   G C T   S Y I F  
 V I L    L F L    Y A M   L K N S   Y S I   S F A K       L   
  W I L  Y M P M  V Y R D           L V R T   S R G            
                   C I A             I D F   K E S K           
                        N               K L                    
    

    UniProt | I-TASSER | AlphaFold | HORDE | GeneCards
Odorant EC50 Adjusted Top Antagonist? Aroma Notes
fructone -5.9 1 7 1  apple, fruity, green, plum, sweet, tropical, woody
maltyl isobutyrate -5.8 1 7 1  berry, caramellic, cotton_candy, fruity, strawberry, sweet, tropical
alpha-damascone -4.7 1 8 1  apple, currant, floral, fruity, rose
manzanate -4.5 1 7.5 1  apple, fresh, fruity, green, melon, natural, pineapple, waxy
vanillin -4 1 7.5 1  chocolate, creamy, sweet, vanilla
eugenyl acetate -4 1 -  carnation, clove, floral, fresh, malty, spicy, sweet, woody

1.) D. Gonzalez-Kristeller, J.B.P. do Nascimento, P.A.F. Galante, B. Malnic, Identification of agonists for a group of human odorant receptors, Front. Pharmacol. 6 (2015)