Olfactory Receptor family 5 subfamily AC member 2.
Estimated Expression: 76% of the population.
Expression estimate based on data from Verbeurgt et al (2014).
Sequence:
10 20 30 40 50 60 70 80 90 100 MDISEGNKTL VTEFVLTGLT DRPWLHVLFF VVFLVVYLIT MVGNLGLIVL IWNDPHLHMP MYLFLGGLAF SDACTSTSIT PRMLVNFLDK TAMISLAECI 110 120 130 140 150 160 170 180 190 200 TQFYFFASSA TTECFLLVMM AYDRYVAICN PLLYPVMMSN KLSAQLLSIS YVIGFLHPLV HVSLLLRLTF CRFNIIHYFY CEILQLFKIS CNGPSINALM 210 220 230 240 250 260 270 280 290 300 IFIFGAFIQI PTLMTIIISY TRVLFDILKK KSEKGRSKAF STCGAHLLSV SLYYGTLIFM YVRPASGLAE DQDKVYSLFY TIIIPLLNPF IYSLRNKKVM 310 HALRRVIRK
Transmembrane Helices:
TMR7 TMR6 TMR5 TMR4 TMR3 TMR2 TMR1 D Q D E A P I S P G L L S I M A L F L W P R Y V K R V Y M L A N S V H V E A L N V L L V H Y F L S F I L I F I M L P H Q T I C M R P T V V F F I I T T G Y Y A G F L F G I F Y F I S T V L F L L P I L S V I Q I F V Y S S S A F S T C A I L Y V F P N S L L H L T P I S L L T T A D S F V M T Y I A G C I I T M Q A S L F C E A L G G G L N G T S F A Y S I L K N S M V L L F L V I L K S R L V R T D Y A M Y M P M N W I L G K E S I D F V Y R D K K L N C I A UniProt | I-TASSER | AlphaFold | HORDE | GeneCards | ORDB
| Odorant | EC50 | Adjusted Top | Antagonist? | Aroma Notes |
|---|---|---|---|---|
| fructone | -5.9 1 | 7 1 | apple, fruity, green, plum, sweet, tropical, woody | |
| maltyl isobutyrate | -5.8 1 | 7 1 | berry, caramellic, cotton_candy, fruity, strawberry, sweet, tropical | |
| alpha-damascone | -4.7 1 | 8 1 | floral, rose, apple, fruity, black_currant, sweet, green, berry | |
| manzanate | -4.5 1 | 7.5 1 | fresh, fruity, green, melon, apple_skin, pineapple, natural, waxy | |
| vanillin | -4 1 | 7.5 1 | chocolate, creamy, sweet, vanilla | |
| eugenyl acetate | -4 1 | (agonist) 1 | carnation, clove, floral, fresh, malty, spicy, sweet, woody |
| Prot. | Sim. | Expr. | 2.53 | 3.29 | 3.32 | 3.33 | 3.36 | 3.37 | 3.40 | 3.41 | 4.53 | 4.56 | 4.57 | 4.60 | 45.49 | 45.51 | 45.52 | 45.53 | 5.39 | 5.42 | 5.43 | 5.46 | 5.47 | 6.48 | 6.51 | 6.55 | 6.59 | 7.38 | 7.39 | 7.41 | 7.42 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| OR5AC2 | 100 | 76% | T | F | F | A | A | T | C | F | G | H | P | H | Y | E | I | L | I | F | G | I | Q | Y | L | Y | A | S | L | Y | T |
| OR5H14 | 94 | 92% | L | L | F | A | V | T | C | F | G | H | A | H | Y | D | I | I | V | F | A | I | Q | Y | L | Y | A | S | L | Y | T |
| OR5H6 | 93 | 57% | L | F | L | V | V | T | C | F | G | H | A | H | Y | D | I | I | V | F | A | V | Q | Y | L | Y | A | S | L | Y | T |
| OR5H2 | 90 | 65% | I | F | F | A | G | T | C | F | G | H | A | H | Y | D | I | I | V | L | S | I | Q | Y | L | Y | A | S | V | Y | T |
| OR5T3 | 89 | 50% | Y | M | F | V | G | T | C | F | G | H | A | H | F | D | M | P | L | F | V | I | E | H | I | Y | S | S | I | Y | T |
| OR5T2 | 88 | 61% | Y | V | A | C | G | T | C | F | G | H | A | H | F | D | I | P | L | F | V | I | E | Y | I | Y | S | S | I | Y | T |
| OR5AR1 | 87 | 53% | Y | F | F | V | V | D | C | Y | G | S | L | H | F | E | I | P | L | L | C | I | E | Y | V | Y | T | S | V | Y | T |
| OR5H1 | 85 | I | F | F | A | V | T | C | F | G | H | A | H | Y | D | T | I | V | F | S | I | Q | Y | L | Y | A | P | L | Y | T | |
| OR5C1 | 84 | 100% | Y | M | F | A | A | D | C | C | G | S | A | H | F | D | I | P | L | I | C | I | Q | Y | L | Y | S | S | V | Y | T |
| OR5H15 | 84 | 96% | I | F | I | A | V | T | C | F | G | H | A | H | Y | D | T | I | V | F | S | I | Q | Y | L | Y | A | P | L | Y | T |
| OR14L1 | 83 | Y | A | F | M | A | T | V | A | G | C | G | H | F | N | I | P | V | F | G | L | V | M | G | Y | I | S | A | Y | T | |
| OR8D1 | 83 | 96% | Y | L | F | V | V | V | G | Y | G | S | A | H | F | D | V | L | L | I | A | N | T | F | I | Y | P | S | V | Y | T |
| OR8B4 | 82 | 61% | Y | L | F | C | V | N | C | Y | G | G | A | H | L | D | V | L | F | V | V | I | T | F | G | Y | T | S | V | Y | T |
| OR5I1 | 82 | 46% | Y | F | F | C | A | D | S | F | G | S | S | H | F | D | L | P | L | Y | G | V | E | Q | L | Y | S | S | V | Y | T |
| OR5W2 | 82 | 46% | Y | F | F | C | A | D | C | L | G | D | A | H | F | D | I | P | L | V | F | I | E | Q | L | Y | S | S | L | Y | T |
| OR5T1 | 81 | 88% | Y | M | A | C | G | T | C | F | S | H | A | H | F | N | M | P | F | F | V | I | E | H | I | Y | S | S | I | Y | T |
| OR5B21 | 81 | 100% | Y | F | F | V | A | T | C | Y | G | N | A | H | F | D | I | P | V | V | A | N | V | Y | I | Y | N | S | V | Y | T |
| OR9Q2 | 81 | 100% | Y | F | F | T | A | S | C | Y | G | S | A | R | F | D | L | P | I | F | A | V | M | F | L | Y | N | S | V | Y | T |
| OR5K3 | 81 | 92% | C | F | L | C | E | T | C | F | G | H | P | E | F | D | V | L | L | L | A | I | Q | C | L | Y | G | A | I | Y | T |
| OR14J1 | 81 | 88% | F | V | F | I | A | S | V | A | G | S | G | H | F | D | V | P | L | F | T | A | A | L | A | F | P | S | V | Y | T |
| OR9Q1 | 80 | 96% | Y | F | F | T | G | S | C | Y | G | S | A | R | F | D | L | P | I | F | A | V | I | F | L | Y | N | S | V | Y | T |
| OR5AS1 | 80 | 73% | C | M | F | A | A | D | C | L | G | T | S | H | F | D | I | P | L | L | C | I | Q | Y | L | Y | T | A | V | Y | T |
| OR1J1 | 80 | 100% | F | T | F | I | A | D | S | F | A | C | A | H | F | D | L | G | I | A | A | A | I | Y | I | Y | P | S | V | Y | T |