Olfactory Receptor family 9 subfamily Q member 2.
Estimated Expression: 100% of the population.
Expression estimate based on data from Verbeurgt et al (2014).
Sequence:
10 20 30 40 50 60 70 80 90 100 MAERNYTVVT EFFLTAFTEH LQWRVPLFLI FLSFYLATML GNTGMILLIR GDRRLHTPMY FFLSHLSLVD ICYSSAIIPQ MLAVLWEHGT TISQARCAAQ 110 120 130 140 150 160 170 180 190 200 FFLFTFFASI DCYLLAIMAY DRYTAVCQPL LYVTIITEKA RWGLVTGAYV AGFFSAFVRT VTAFTLSFCG NNEINFIFCD LPPLLKLSCG DSYTQEVVII 210 220 230 240 250 260 270 280 290 300 VFALFVMPAC ILVILVSYLF IIVAILQIHS AGGRAKTFST CASHLTAVAL FFGTLIFMYL RDNTGQSSEG DRVVSVLYTV VTPMLNPLIY SLRNKEVKEA 310 320 TRKALSKSKP ARRP
Transmembrane Helices:
TMR7 TMR6 TMR5 TMR4 TMR3 TMR2 TMR1 D G E S N D T Y S D A T S I T T W L W Q L H V V R R L Y M V E Q V T R V R A Q V A L P V R Y L V S F I L V I I V F A S Q A A C M Q P I I L F L V V T T G F F L A F F F G A L F F I A S S L F L M P T L A V P M V F V Y A F F T F S Y C I A L Y F L P N A T L H I C A G T V L I S A D V L L M T Y I S A C L I V L G W R L Y C D S L H S G T N G T S F T Y S V A K E T I A L L F F L I M K A R I I F L D Y A M Y M P T G R I L G G A S I A V T Y R D I Q L Q C V A UniProt | I-TASSER | AlphaFold | HORDE | GeneCards
| Odorant | EC50 | Adjusted Top | Antagonist? | Aroma Notes |
|---|---|---|---|---|
| p-cresol | -5.55 1 | 29 1 | phenolic, narcissus, animal, mimosa | |
| p-cresyl acetate | -4.82 2 | (agonist) 2 | narcissus, phenolic, animal | |
| p-cresyl isobutyrate | -4.1 3 | (agonist) 3 | animal, floral, lily, narcissus, green, fruity | |
| lepidine | -3.92 3 | (agonist) 3 | burnt, oily, herbal, floral, sweet | |
| muscone | - | 0 3 | musk, animal, powdery | |
| acetylcedrene | - | 0 4 | Y 4 | warm, woody, amber, musk |
| amber butanol | - | 0 4 | Y 4 | woody, amber, ambrette |
| bourgeonal | - | 0 5 | Y 5 | fresh, watery, floral, cyclamen, sweet |
| isolongifolanone | - | 0 4 | Y 4 | dry, woody, patchouli, cedar, earthy, tobacco, incense |
| nectaryl | - | 0 5 | Y 5 | fruity, tropical, lactonic, peach, apricot, oily, waxy, custard, coconut |
| nerolidol | - | 0 4 | Y 4 | floral, green, waxy, citrus, woody, fruity, melon |
| sandranol | - | 0 4 | Y 4 | woody, sandalwood, greasy, oily, waxy |
1.) Roger EmterAndreas Natsch Modified olfactory receptors WO2024126820A1
2.) Shirai, T., Takase, D., Yokoyama, J. et al. Functions of human olfactory mucus and age-dependent changes. Sci Rep 13, 971 (2023). https://doi.org/10.1038/s41598-023-27937-1
3.) Keiichi Yoshikawa, Naoko Saito (2016) Method for selecting odor-controlling substance EP3305898B1
4.) Keiichi Yoshikawa, Naoko Saito, Aya Namba, Ichiro Mori (2017) Urine odor suppressor WO2017090518A1
5.) Aya Namba, Naoko Saito, Keiichi Yoshikawa, Ichiro Mori (2015) Search method of urine odor suppressor JP2015211667A
| Prot. | Sim. | Expr. | 2.53 | 3.29 | 3.32 | 3.33 | 3.36 | 3.37 | 3.40 | 3.41 | 4.53 | 4.56 | 4.57 | 4.60 | 45.49 | 45.51 | 45.52 | 45.53 | 5.39 | 5.42 | 5.43 | 5.46 | 5.47 | 6.48 | 6.51 | 6.55 | 6.59 | 7.38 | 7.39 | 7.41 | 7.42 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| OR9Q2 | 100 | 100% | Y | F | F | T | A | S | C | Y | G | S | A | R | F | D | L | P | I | F | A | V | M | F | L | Y | N | S | V | Y | T |
| OR9Q1 | 99 | 96% | Y | F | F | T | G | S | C | Y | G | S | A | R | F | D | L | P | I | F | A | V | I | F | L | Y | N | S | V | Y | T |
| OR9I1 | 92 | 96% | Y | F | F | T | A | G | C | F | G | G | A | R | F | D | L | P | I | F | G | V | I | F | L | Y | S | S | V | Y | T |
| OR5B21 | 87 | 100% | Y | F | F | V | A | T | C | Y | G | N | A | H | F | D | I | P | V | V | A | N | V | Y | I | Y | N | S | V | Y | T |
| OR5AR1 | 84 | 53% | Y | F | F | V | V | D | C | Y | G | S | L | H | F | E | I | P | L | L | C | I | E | Y | V | Y | T | S | V | Y | T |
| OR2M3 | 84 | 100% | L | I | Y | T | L | G | C | F | G | D | G | D | F | D | F | P | L | C | C | M | I | Y | A | Y | T | S | V | Y | T |
| OR5T2 | 83 | 61% | Y | V | A | C | G | T | C | F | G | H | A | H | F | D | I | P | L | F | V | I | E | Y | I | Y | S | S | I | Y | T |
| OR5W2 | 82 | 46% | Y | F | F | C | A | D | C | L | G | D | A | H | F | D | I | P | L | V | F | I | E | Q | L | Y | S | S | L | Y | T |
| OR11L1 | 82 | 100% | Y | L | F | V | G | A | C | F | G | T | G | P | F | D | L | P | I | L | S | V | L | Y | M | Y | S | S | V | Y | T |
| OR5C1 | 82 | 100% | Y | M | F | A | A | D | C | C | G | S | A | H | F | D | I | P | L | I | C | I | Q | Y | L | Y | S | S | V | Y | T |
| OR8B4 | 81 | 61% | Y | L | F | C | V | N | C | Y | G | G | A | H | L | D | V | L | F | V | V | I | T | F | G | Y | T | S | V | Y | T |
| OR5A1 | 81 | 100% | Y | F | F | V | G | L | C | L | G | S | S | Q | F | D | L | P | N | V | V | V | G | F | A | Y | S | S | V | Y | S |
| OR2D3 | 81 | 100% | F | I | F | L | G | C | C | A | G | V | S | D | F | E | P | P | I | M | G | I | L | Y | G | Y | N | S | V | Y | T |
| OR5T3 | 81 | 50% | Y | M | F | V | G | T | C | F | G | H | A | H | F | D | M | P | L | F | V | I | E | H | I | Y | S | S | I | Y | T |
| OR2Z1 | 81 | 84% | C | I | L | T | G | V | G | V | G | N | A | Q | F | E | V | P | L | S | G | I | L | Y | A | Y | C | S | L | Y | S |
| OR11H6 | 81 | 96% | Y | F | F | F | G | T | C | F | G | C | Y | P | V | D | P | G | C | F | N | I | I | Y | L | Y | T | T | L | Y | T |
| OR2B11 | 81 | 100% | Y | Y | F | H | G | C | C | I | G | N | S | Q | F | E | V | P | L | L | V | F | V | Y | A | Y | P | S | L | Y | S |
| OR2M5 | 80 | 34% | L | I | Y | V | L | G | C | F | G | D | A | D | F | D | F | P | L | C | C | M | I | Y | G | Y | T | S | V | Y | T |
| OR14L1 | 80 | Y | A | F | M | A | T | V | A | G | C | G | H | F | N | I | P | V | F | G | L | V | M | G | Y | I | S | A | Y | T | |
| OR5I1 | 80 | 46% | Y | F | F | C | A | D | S | F | G | S | S | H | F | D | L | P | L | Y | G | V | E | Q | L | Y | S | S | V | Y | T |
| OR5AP2 | 80 | 61% | Y | F | F | G | L | G | C | F | G | N | A | H | Y | D | T | P | I | F | S | I | V | F | I | Y | T | S | V | Y | T |
| OR5J2 | 80 | 57% | Y | H | F | G | I | T | G | F | G | N | T | H | F | D | I | P | L | F | S | I | A | Y | L | Y | S | S | M | Y | T |
| OR8D4 | 80 | 96% | Y | L | F | C | V | I | C | Y | G | D | A | H | F | D | I | V | I | I | G | N | M | Y | L | Y | A | S | V | Y | T |
| OR10K2 | 80 | 96% | Y | M | F | L | G | C | S | F | G | V | A | I | F | D | I | A | I | L | C | V | L | Y | A | Y | Q | S | V | Y | T |
| OR5B3 | 80 | 88% | Y | M | F | V | A | T | N | Y | G | N | A | H | F | D | I | P | L | V | V | N | I | Y | I | Y | S | P | V | Y | T |
| OR10W1 | 80 | 100% | Y | M | F | I | G | S | C | F | G | L | S | L | F | D | V | P | V | A | A | A | I | Y | C | Y | S | S | L | Y | T |
| OR5AK3 | 80 | Y | F | Y | A | A | T | C | Y | G | N | A | H | F | D | G | L | D | F | V | D | L | Y | L | Y | Q | S | I | Y | G |