Olfactory Receptor family 5 subfamily I member 1.
Sequence:
10 20 30 40 50 60 70 80 90 100 MEFTDRNYTL VTEFILLGFP TRPELQIVLF LMFLTLYAII LIGNIGLMLL IRIDPHLQTP MYFFLSNLSF VDLCYFSDIV PKMLVNFLSE NKSISYYGCA 110 120 130 140 150 160 170 180 190 200 LQFYFFCTFA DTESFILAAM AYDRYVAICN PLLYTVVMSR GICMRLIVLS YLGGNMSSLV HTSFAFILKY CDKNVINHFF CDLPPLLKLS CTDTTINEWL 210 220 230 240 250 260 270 280 290 300 LSTYGSSVEI ICFIIIIISY FFILLSVLKI RSFSGRKKTF STCASHLTSV TIYQGTLLFI YSRPSYLYSP NTDKIISVFY TIFIPVLNPL IYSLRNKDVK 310 320 DAAEKVLRSK VDSS
Transmembrane Helices:
TMR1 TMR2 TMR3 TMR4 TMR5 TMR6 TMR7 L E P R F G Y Y S F I T T D R T N P S V I Q N V L L A C S T H V W E N S Y I F I K D M L F L M K P V F Y F Q L S S T S L L L L T F V S I T L F I D S T C F M N G G S G Y G Q Y I I T Y I A Y L F Y C L T D A F L Y S I E V S T V S V P I F I L I D V F F S E L V I L F C I T L H S P N L G I N G S L N S A A L I R M C I I I I A C T S Y I L L M L L F F Y A M I G R S Y S I S F T K L R I L Y M P T V Y R D L I F F K R G C I A V S L S F S R N K L UniProt | I-TASSER | AlphaFold | HORDE | GeneCards
| Odorant | EC50 | Adjusted Top | Antagonist? | Aroma Notes |
|---|---|---|---|---|
| aldehyde C-8 | - | 1.9231 1 | aldehydic, citrus, fatty, green, orange, peel, waxy | |
| acetic acid | - | 0 1 | acrid, sharp, vinegar | |
| 2-aminoacetophenone | - | 0 1 | grape, sweet, musty | |
| androstenone | - | 0 1 | animal, musky | |
| anisaldehyde | - | 0 1 | anisic, balsamic, floral, hawthorn, mimosa, powdery, sweet | |
| benzaldehyde | - | 0 1 | sharp, sweet, bitter, almond, cherry | |
| 2-butanone | - | 0 1 | acetone, camphoraceous, ethereal, fruity | |
| calone | - | 0 1 | fresh, watery, clean, melon, green, marine, ozone, phenolic | |
| caproic acid | - | 0 1 | cheesy, fatty, sour, sweaty | |
| cedramber | - | 0 1 | woody, dry, cedar, ambergris, earthy, vetiver | |
| cinnamyl alcohol | - | 0 1 | balsamic, cinnamon, cinnamyl, fermented, floral, green, hyacinth, powdery, spicy, sweet | |
| civetone | - | 0 1 | animal, clean, dry, musk, sweet | |
| beta-damascone | - | 0 1 | berry, currant, floral, fruity, honey, plum, rose, tobacco | |
| geosmin | - | 0 1 | earthy, fresh, musty, soil | |
| geraniol | - | 0 1 | citrus, floral, fruity, rose, sweet, waxy | |
| globanone | - | 0 1 | animal, balsamic, cloth, dry, floral, laundered, musk, tobacco, waxy | |
| habanolide | - | 0 1 | animal, cloth, dry, laundered, metallic, musk, powdery, sweet, tropical, waxy | |
| hedione | - | 0 1 | floral, green, jasmine, lactonic, natural, oily, tropical | |
| heptanal | - | 0 2 | aldehydic, cognac, fatty, fresh, green, herbal, ozone | |
| hexanal | - | 0 1 | aldehydic, fatty, fresh, fruity, grass, green, leafy, sweaty | |
| 1-hexanol | - | 0 1 | alcoholic, ethereal, fruity, fusel, green, herbal, oily, pungent, sweet | |
| isobutyraldehyde | - | 0 1 | cereal, malty | |
| isovaleric acid | - | 0 1 | cheesy, sour, sweaty, tropical | |
| maltol | - | 0 1 | baked, bread, caramellic, cotton_candy, fruity, jammy, sweet | |
| 4-methylvaleric acid | - | 0 1 | cheesy, pungent | |
| muguet propanol | - | 0 1 | floral, lily_of_the_valley, woody | |
| muscone | - | 0 1 | animal, fatty, musk, natural, powdery, sweet | |
| gamma-nonalactone | - | 0 1 | buttery, coconut, creamy, oily, sweet, waxy | |
| 1-octen-3-one | - | 0 1 | earthy, metallic, mushroom | |
| pentadecalactone | - | 0 1 | animal, fruity, musk, natural, powdery | |
| 3-phenylpropionic aldehyde | - | 0 1 | balsamic, cortex, foliage, fresh, green, leafy, storax | |
| propionic acid | - | 0 1 | acidic, cheesy, pungent, vinegar | |
| sandranol | - | 0 1 | woody, sandalwood, greasy, oily, waxy | |
| timberol | - | 0 1 | amber, dry, powdery, sandalwood, sawdust, woody | |
| 2,4,6-trichloroanisole | - | 0 1 | cork_taint | |
| ysamber | - | 0 1 | dry, woody, vetiver, amber, powdery, musk, fruity |
1.) Ashti Baghaei, K. (2015). Large scale analysis of olfactory receptors with highly genetically variations in relation with specific anosmia (Doctoral dissertation, Bochum, Ruhr-Universität Bochum, Diss., 2013).
2.) Lim J. H., J. Park, E. H. Oh, H. J. Ko, S. Hong, and Park, T. H. (2014) Nanovesicle-based bioelectronic nose for the diagnosis of lung cancer from human blood. Adv. Healthcare Mater., 3: 360–366.