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Olfactory Receptor family 7 subfamily A member 5.

Sequence:

        10         20         30         40         50         60         70         80         90        100 
MEPGNDTQIS EFLLLGFSQE PGLQPFLFGL FLSMYLVTVL GNLLIILATI SDSHLHTPMY FFLSNLSFAD ICVTSTTIPK MLMNIQTQNK VITYIACLMQ 

       110        120        130        140        150        160        170        180        190        200 
MYFFILFAGF ENFLLSVMAY DRFVAICHPL HYMVIMNPHL CGLLVLASWT MSALYSLLQI LMVVRLSFCT ALEIPHFFCE LNQVIQLACS DSFLNHMVIY 

       210        220        230        240        250        260        270        280        290        300 
FTVALLGGGP LTGILYSYSK IISSIHAISS AQGKYKAFST CASHLSVVSL FYGAILGVYL SSAATRNSHS SATASVMYTV VTPMLNPFIY SLRNKDIKRA 

       310        320 
LGIHLLWGTM KGQFFKKCP

Transmembrane Helices:

  TMR1     TMR2     TMR3     TMR4     TMR5     TMR6     TMR7   

L G P E   N M L   A I Y T     V M   L F S D      V G  S H S N  
 F P Q   M K P I   M L C   L I Q L   M H N    L I A    T A S   
L G F L   T T S   F Y M Q   L S Y   F Y I V  G Y F L  M V S A  
 S L F   T V C I   L I F   L A S M   A V T    S V V    V T Y   
V L Y M   D A F   F G A F   T W S   G G L L  S L H S  M P T V  
 L V T   S L N S   F N E   A L V L   L P G    A C T    P N L   
L L N G   L F F   V S L L   L G C   L I G T  S F A K  S Y I F  
 L I I   Y M P T   Y A M   L H P N   Y S Y    Y K G        L   
  I T A           V F R D           I I K S  Q A S S           
                   C I A             I S S                     
                        H               A H                    
    

    UniProt | I-TASSER | AlphaFold | HORDE | GeneCards
Odorant EC50 Adjusted Top Antagonist? Aroma Notes
myrac aldehyde - 8.3333 1  aldehydic, citrus, floral, greasy, marine
furaneol - 6 2  sweet, cotton_candy, caramellic, strawberry, brown_sugar
caramel furanone - 0 2  burnt, caramellic, coffee, maple, sugar, sweet
beta-damascenone - 0 2  floral, fruity, grape, natural, plum, raspberry, rose, sugar, sweet
beta-ionone - 0 2  beeswax, berry, floral, fruity, sweet, tropical, woody, fragrant, sour, acid, vinegar, sharp, pungent
1-octen-3-one - 0 2  earthy, metallic, mushroom
phenylacetic acid - 0 2  sweet, honey, floral, honeysuckle, sour, waxy, civet

1.) Veitinger T, Riffell JR, Veitinger S, Nascimento JM, Triller A, Chandsawangbhuwana C, Schwane K, Geerts A, Wunder F, Berns MW, Neuhaus EM, Zimmer RK, Spehr M, Hatt H. Chemosensory Ca2+ dynamics correlate with diverse behavioral phenotypes in human sperm. J Biol Chem. 2011 May 13;286(19):17311-25. doi: 10.1074/jbc.M110.211524. Epub 2011 Mar 21. PMID: 21454470; PMCID: PMC3089573.

2.) Hartmann C, Triller A, Spehr M, Dittrich R, Hatt H, Buettner A. Sperm-Activating Odorous Substances in Human Follicular Fluid and Vaginal Secretion: Identification by Gas Chromatography–Olfactometry and Ca2 Imaging. Chempluschem 78: 695–702, 2013. doi:10.1002/cplu.201300008