OR1C1

Olfactory Receptor family 1 subfamily C member 1.

Estimated Expression: 100% of the population.

Expression estimate based on data from Verbeurgt et al (2014).

Sequence:

        10         20         30         40         50         60         70         80         90        100 
MEKRNLTVVR EFVLLGLPSS AEQQHLLSVL FLCMYLATTL GNMLIIATIG FDSHLHSPMY FFLSNLAFVD ICFTSTTVPQ MVVNILTGTK TISFAGCLTQ 

       110        120        130        140        150        160        170        180        190        200 
LFFFVSFVNM DSLLLCVMAY DRYVAICHPL HYTARMNLCL CVQLVAGLWL VTYLHALLHT VLIAQLSFCA SNIIHHFFCD LNPLLQLSCS DVSFNVMIIF 

       210        220        230        240        250        260        270        280        290        300 
AVGGLLALTP LVCILVSYGL IFSTVLKITS TQGKQRAVST CSCHLSVVVL FYGTAIAVYF SPSSPHMPES DTLSTIMYSM VAPMLNPFIY TLRNRDMKRG 

       310        320 
LQKMLLKCTV FQQQ

Transmembrane Helices:

  TMR7     TMR6     TMR5     TMR4     TMR3     TMR2     TMR1   


D S E P       P   F S V D     I L   S I T K      L I  Q E A S  
 S L T   S S P S   M V N   V T H L   G A F    N V V    L H Q   
Y M I T   F Y V   A F I I   L A H   Q T L C  M Q P V  L V S L  
 V M S   A I A T   G G V   L Y T V   F F L    T T S    C L F   
L M P A   G Y F   L A L L   L W L   F S V F  T F C I  A L Y M  
 F P N   L V V V   L P T   G A V L   M N V    D V F    L T T   
    Y I   S L H   L I C V   Q V C   L L S D  A L N S  L M N G  
         C S C T   Y S V   L C L N   V C L    L F F    A I I   
          S V A   F I L G           D Y A M  Y M P S  F G I T  
         R Q K G   V T S             V Y R                 D   
                    I K L           H C I A                    
    

    UniProt | I-TASSER | AlphaFold | HORDE | GeneCards | ORDB 2

Odorant	EC₅₀	Adjusted Top	Aroma Notes
linalool	-7.86 ¹	10 ¹	blueberry, bois_de_rose, citrus, floral, green, rose, sweet, woody
coumarin	-6 ²	2.6667 ²	coumarinic, hay, sweet, tonka
pelargonic acid	-	2.3333 ²	cheesy, dairy, dirty, waxy
androstenone	-	1 ²	animal, musky
allyl phenylacetate	-	0 ²	honey, fruity, rummy
n-amyl alcohol	-	0 ²	fusel, oily, sweet, balsamic, pungent, fermented, bready, yeasty, winey, solvent
amyl hexanoate	-	0 ²	sweet, green, fruity, estery, pineapple, apple, pear, fatty, waxy, cognac, melon
l-arabinose	-	0 ²
benzene	-	0 ²	gasoline, phenolic, solvent, cinnamon
butyl formate	-	0 ²	fruity, plum, rummy, brandy
butyric acid	-	0 ²	sharp, acetic, cheesy, buttery, fruity, dairy, creamy
(S)-(+)-carvone	-	0 ²	bready, caraway, minty, spicy
citral	-	0 ²	sharp, lemon, sweet, fresh, juicy, lemon_peel, tart, green, citrus, lime, woody, herbal
coffee difuran	-	0 ²	cabbage, chicken, coffee, meaty, onion, roasted, sulfurous, cocoa, earthy, fungal, mild, mushroom, nutty
beta-damascone	-	0 ²	berry, currant, floral, fruity, honey, plum, rose, tobacco
decanal	-	0 ²	sweet, aldehydic, waxy, orange_peel, citrus, floral
dimethyl disulfide	-	0 ²	sulfurous, vegetable, cabbage, onion, malty, creamy
2,4-DNT	-	0 ²
2-ethyl fenchol	-	0 ²	camphorous, earthy, humus, mushroom, musty, patchouli, potato, rooty, tea
ethyl vanillin	-	0 ²	sweet, creamy, vanilla, caramellic
eugenol	-	0 ²	clove, spicy, sweet, woody
eugenyl acetate	-	0 ²	carnation, clove, floral, fresh, malty, spicy, sweet, woody
helional	-	0 ²	cyclamen, fresh, green, hay, ozone, watery
2-heptanone	-	0 ²	banana, cheesy, coconut, creamy, fruity, green, herbal, ketonic, spicy, sweet, waxy, woody
(Z)-3-hexen-1-ol	-	0 ²	fresh, green, grassy, foliage, vegetable, herbal, oily, melon_rind, pungent, lettuce
isobutylamine	-	0 ²	cheesy, fishy
d-limonene	-	0 ²	citrus, orange, fresh, sweet
lyral	-	0 ²	aquatic, clean, cyclamen, floral, muguet, rhubarb, watery, waxy, woody
(1S,2R,5S)-(+)-menthol	-	0 ²	cooling, mentholic, minty, fresh, sweet, herbal
methyl eugenol	-	0 ²	carnation, cinnamon, clove, fresh, spicy, sweet, warm
methyl furfuryl disulfide	-	0 ²	sulfurous, coffee, roasted, alliaceous, meaty, liver, onion, garlic, eggy
methyl salicylate	-	0 ²	minty, wintergreen
nonanal	-	0 ²	waxy, aldehydic, rose, fresh, orris, orange_peel, fatty, peely
octanethiol	-	0 ²	sulfurous
1-octanol	-	0 ²	aldehydic, green, mushroom, orange, rose, waxy
octyl octanoate	-	0 ²	coconut, oily, fruity
propanal	-	0 ²	alcoholic, cocoa, earthy, nutty, whisky, winey
propionic acid	-	0 ²	acidic, cheesy, pungent, vinegar
pyrazine	-	0 ²	pungent, sweet, corn, roasted, hazelnut, barley
quinoline	-	0 ²	earthy, medicinal, musty, rubbery, tobacco
terpinyl acetate	-	0 ²	bergamot, citrus, herbal, lavender, lime

1.) Roger EmterAndreas Natsch Modified olfactory receptors WO2024126820A1

2.) Adipietro KA, Mainland JD, Matsunami H (2012) Functional Evolution of Mammalian Odorant Receptors. PLoS Genet 8(7): e1002821. doi:10.1371/ journal.pgen.1002821

Prot.	Sim.	Expr.	2.53	3.29	3.32	3.33	3.36	3.37	3.40	3.41	4.53	4.56	4.57	4.60	45.49	45.51	45.52	45.53	5.39	5.42	5.43	5.46	5.47	6.48	6.51	6.55	6.59	7.38	7.39	7.41	7.42
OR1C1	100	100%	F	L	F	V	V	N	S	L	T	H	A	H	F	D	L	N	I	V	G	L	A	Y	A	Y	S	T	I	Y	S
OR1E1	92	80%	F	M	F	L	G	D	S	F	T	H	A	H	F	D	M	S	I	M	G	I	L	Y	V	Y	S	A	M	Y	T
OR1E2	89	80%	F	M	F	L	S	D	S	F	T	H	A	H	F	D	M	S	I	M	G	I	L	Y	V	Y	S	A	M	Y	T
OR7E24	87	96%	F	M	F	V	A	C	D	M	S	D	S	H	F	D	P	S	I	M	G	F	G	Y	G	Y	S	S	V	Y	T
OR1J4	84	100%	L	M	F	I	T	D	N	F	S	N	A	H	F	D	L	V	I	V	G	V	I	Y	I	Y	S	S	V	Y	T
OR1N1	84	96%	L	M	F	L	G	D	S	F	T	V	A	H	F	D	I	T	V	L	G	V	L	Y	L	Y	P	A	A	Y	T
OR1A1	84	73%	F	M	M	I	G	N	S	Y	G	N	A	H	Y	D	I	T	M	L	G	I	F	Y	V	Y	L	T	V	Y	T
OR10K1	84	100%	Y	M	F	L	G	S	S	F	G	V	S	T	F	D	I	S	I	L	G	A	L	Y	A	Y	K	S	V	Y	T
OR1L3	83	100%	Y	M	F	L	G	N	S	Y	S	H	S	H	F	D	V	N	A	E	G	S	V	Y	I	Y	L	T	I	Y	T
OR7G3	82		F	I	V	L	V	G	N	G	S	D	A	H	F	E	L	A	V	V	T	L	G	Y	G	Y	S	S	V	Y	T
OR8U9	82	80%	Y	L	F	L	M	T	C	L	S	V	A	H	Y	D	D	M	I	C	A	M	F	Y	L	Y	S	S	V	Y	T
OR5T3	82	50%	Y	M	F	V	G	T	C	F	G	H	A	H	F	D	M	P	L	F	V	I	E	H	I	Y	S	S	I	Y	T
OR1J2	82	100%	F	M	F	I	T	D	S	F	S	S	S	H	F	D	L	A	M	V	G	V	I	Y	I	Y	T	A	L	Y	T
OR2AG1	81	100%	F	M	A	L	G	G	D	L	A	S	A	Y	L	E	I	P	V	M	G	F	L	Y	A	Y	S	S	V	Y	T
OR1Q1	81	100%	F	T	F	I	A	V	N	F	S	H	A	H	F	D	L	Y	I	E	G	V	I	Y	L	Y	L	T	V	Y	T
OR1E3	81		F	M	H	L	G	V	S	F	T	H	A	H	F	D	T	S	M	M	G	I	L	Y	I	Y	L	A	V	Y	T
OR7C2	81	53%	F	I	F	I	G	C	N	L	S	G	S	E	F	D	P	S	M	V	T	L	G	Y	G	Y	S	S	V	Y	T
OR5T1	81	88%	Y	M	A	C	G	T	C	F	S	H	A	H	F	N	M	P	F	F	V	I	E	H	I	Y	S	S	I	Y	T
OR8U1	81	80%	Y	L	F	L	M	I	S	L	S	M	A	H	Y	D	D	M	I	C	A	M	F	Y	L	Y	S	S	V	Y	T
OR7A10	81	73%	F	M	F	L	V	G	N	F	S	N	S	Q	F	E	I	N	M	A	V	L	G	Y	C	Y	S	S	V	Y	T
OR5C1	80	100%	Y	M	F	A	A	D	C	C	G	S	A	H	F	D	I	P	L	I	C	I	Q	Y	L	Y	S	S	V	Y	T
OR5T2	80	61%	Y	V	A	C	G	T	C	F	G	H	A	H	F	D	I	P	L	F	V	I	E	Y	I	Y	S	S	I	Y	T
OR7A2	80		F	M	F	V	I	V	S	L	S	N	S	Q	F	E	L	N	M	A	A	L	D	Y	G	Y	S	S	V	Y	T
OR2AG2	80	100%	F	M	A	L	G	S	D	L	A	I	A	H	L	E	I	P	I	T	G	F	L	Y	A	Y	S	S	V	Y	T
OR7A5	80	100%	V	M	F	I	A	G	N	F	S	Y	S	Q	F	E	L	N	I	T	V	L	G	Y	I	Y	S	S	V	Y	T
OR5AR1	80	53%	Y	F	F	V	V	D	C	Y	G	S	L	H	F	E	I	P	L	L	C	I	E	Y	V	Y	T	S	V	Y	T
OR1F1	80	30%	F	M	V	F	V	D	N	F	A	N	V	H	F	D	V	T	I	E	G	V	M	Y	I	Y	L	T	V	Y	T
OR1K1	80	100%	F	M	F	F	G	V	S	C	S	H	S	Y	F	D	H	Q	I	E	G	V	V	Y	V	Y	T	T	V	Y	T

Active model:	text	3D	download
Inactive model:	text	3D	download
Active dock:	text	3D	download
Inactive dock:	text	3D	download
JSON entry:	text		download