Olfactory Receptor family 8 subfamily H member 1.
Sequence:
10 20 30 40 50 60 70 80 90 100 MGRRNNTNVP DFILTGLSDS EEVQMALFIL FLLIYLITML GNVGMILIIR LDLQLHTPMY FFLTHLSFID LSYSTVITPK TLANLLTSNY ISFMGCFAQM 110 120 130 140 150 160 170 180 190 200 FFFVFLGAAE CFLLSSMAYD RYVAICSPLR YPVIMSKRLC CALVTGPYVI SFINSFVNVV WMSRLHFCDS NVVRHFFCDT SPILALSCMD TYDIEIMIHI 210 220 230 240 250 260 270 280 290 300 LAGSTLMVSL ITISASYVSI LSTILKINST SGKQKALSTC ASHLLGVTIF YGTMIFTYLK PRKSYSLGRD QVASVFYTIV IPMLNPLIYS LRNKEVKNAL 310 320 IRVMQRRQDS R
Transmembrane Helices:
TMR1 TMR2 TMR3 TMR4 TMR5 TMR6 TMR7 V E E S L G M F S M W D Y T D Y T F R G L S A M Q N A L A F C V V N V I E I I M T V Q D L I F L T K P T F F M Q F S N I H I M G Y F I F V S A L L F I V T F V F I F S I G A L T V G I T Y I L Y I S Y S L A A G L V Y P M L T S L L H S M P I V L M T D I F F C E G T V L L S V A C T P N L G V N G S L H T S S L L A C C S I T I S L A K S Y I L L I M L F F Y A M L R K S Y S A Q K G L R I I Y M P T V Y R D L I S V S T S N C I A I T S S K L UniProt | I-TASSER | AlphaFold | HORDE | GeneCards
| Odorant | EC50 | Adjusted Top | Antagonist? | Aroma Notes |
|---|---|---|---|---|
| skatole | -4.22 1 | 1.9512 1 | animal, civet, fecal, naphthyl | |
| 4-vinylguaiacol | -4.3 2 | 0.4 2 | spicy, clove, carnation, phenolic, peppery, smoky, woody, powdery | |
| indole | -4.22 1 | 0.1626 1 | animal, fecal, floral, naphthyl | |
| oranger crystals | -3.8 3 | 0.6471 3 | honey, neroli, orangeflower, powdery, sweet | |
| (R)-(-)-carvone | -3.5 3 | 0.5294 3 | herbal, minty, spearmint, sweet | |
| allyl cyclohexylpropionate | - | -0.1626 1 | apple, candy, fruity, green, pineapple, sweet, tropical, waxy | |
| delta-damascone | - | -0.1626 1 | fruity, sweet, rose, natural, petal, currant_bud, black_currant_bud, tobacco | |
| (-)-alpha-fenchol | - | -0.1626 1 | camphoraceous, clean, cooling, eucalyptus, green, herbal, minty, piney, woody | |
| hydroxycitronellal | - | -0.1626 1 | floral, green, lily, melon, sweet, tropical, waxy | |
| ivy carbaldehyde | - | -0.1626 1 | green, aldehydic, weedy, herbal, cortex, privet, soapy | |
| cis-jasmone | - | -0.1626 1 | woody, herbal, floral, spicy, jasmine, celery | |
| labienoxime | - | -0.1626 1 | currant_bud, blackcurrant_bud, green, grapefruit, herbal, rose, sage | |
| lilial | - | -0.1626 1 | cumin, floral, green, muguet, powdery, watery | |
| melafleur | - | -0.1626 1 | floral, clean, muguet, ozone, marine, sandy, balsamic | |
| 7-methoxycitronellal | - | -0.1626 1 | fresh, melon, floral, lily, sweet | |
| muscenone | - | -0.1626 1 | animal, musk, soapy | |
| myrac aldehyde | - | -0.1626 1 | aldehydic, citrus, floral, greasy, marine | |
| myraldyl acetate | - | -0.1626 1 | fresh, lily, magnolia, sweet, citrus, freesia, green | |
| thymol | - | -0.1626 1 | camphoraceous, herbal, medicinal, phenolic, thyme | |
| alpha,alpha-dimethyl phenethyl acetate | - | -0.4065 1 | sweet, floral, fruity, rose, green, pear, berry, jasmin, powdery | |
| civetone | - | -0.4065 1 | animal, clean, dry, musk, sweet | |
| cyclamen homoaldehyde | - | -0.4065 1 | floral, muguet, lily, green, tropical, oily, greasy, marine, balsamic | |
| ebanol | - | -0.4065 1 | ||
| ethyl linalyl ether | - | -0.4065 1 | floral | |
| geraniol | - | -0.4065 1 | citrus, floral, fruity, rose, sweet, waxy | |
| grapefruit pentanol | - | -0.4065 1 | vetiver, green, citrus, grapefruit, rhubarb, floral | |
| methyl ionone gamma | - | -0.4065 1 | violet, sweet, orris, powdery, floral, woody | |
| methyl jasmonate | - | -0.4065 1 | jasmin, floral, oily, green, petal, greasy, soft | |
| perillic aldehyde | - | -0.4065 1 | fresh, green, herbal, grassy, sweet, minty, cumin, spicy, citrus | |
| 3-(3-propen-2-yl phenyl) butanal | - | -0.4065 1 | ozone, cortex, green, floral, melon | |
| strawberry glycidate | - | -0.4065 1 | cherry, fruity, grape, jammy, phenolic, strawberry, sweet | |
| gamma-undecalactone | - | -0.4065 1 | apricot, coconut, creamy, fatty, fruity, ketonic, lactonic, peach | |
| verdyl acetate | - | -0.4065 1 | floral, green, soapy, cedar, pine, woody | |
| amber butanol | - | -0.6504 1 | woody, amber, ambrette | |
| ambroxide | - | -0.6504 1 | amber, ambergris, cedar, dry, green, musk, paper, pine, seedy, woody | |
| exaltolide | - | -0.6504 1 | musk, animal, powdery, natural, fruity | |
| galaxolide | - | -0.6504 1 | floral, musk, sweet | |
| galbascone | - | -0.6504 1 | fresh, green, galbanum, earthy, weedy, pineapple, narcissus, hyacinth, fruity | |
| beta-ionone | - | -0.6504 1 | beeswax, berry, floral, fruity, sweet, tropical, woody, fragrant, sour, acid, vinegar, sharp, pungent | |
| (R,S)-methyl cedryl ketone | - | -0.6504 1 | woody, vetiver, amber, leathery, musk, cedar | |
| patchouli hexanol | - | -0.6504 1 | woody, musty, patchouli, camphoreous, minty, leathery | |
| spicy carbonate | - | -0.6504 1 | spicy, woody, floral, green, herbal | |
| tetrahydrogeraniol | - | -0.6504 1 | leathery, musty, plastic, rose, sweet |
1.) Aya Kato, Naoko Saito (2015) Odor control agent. JP5798382B2
2.) Aya Namba, Naoko Saito, Keiichi Yoshikawa, Ichiro Mori (2015) Search method of urine odor suppressor JP2015211667A
3.) Ieki T, Yamanaka Y, Yoshikawa K (2022) Functional analysis of human olfactory receptors with a high basal activity using LNCaP cell line. PLOS ONE 17(4): e0267356.