SMILES:
O=C1C=COC(C)=C1O
Aroma Description:
sweet, caramellic, cotton_candy, jammy, fruity, bread, baked1
| Receptor | Expression | log10 EC50 | Adj. Top | Antagonist? | Correlated Perceptual Qualities |
|---|---|---|---|---|---|
| OR5M3 | 92 | -4.15 5 | - | cotton_candy, brown_sugar, caramellic, maple, burnt_sugar, sugar | |
| OR1B1 | 100 | - | 6.7308 4 | cotton_candy, jammy, sweet, caramellic | |
| OR1G1 | 61 | - | 4.5685 2 | sweet, waxy, citrus, tart, orange, fresh, aldehydic, rose, floral, fatty | |
| OR2W3 | 100 | - | 2.3256 3 | sweet, lemon, citrus, clove | |
| OR52D1 | 100 | - | 1.0152 2 | dairy, cheesy, anise, milky, creamy, sour, sharp, peach, rancid, lactonic | |
| OR5I1 | 46 | - | 0 4 | ||
| OR8D1 | 96 | - | 0 5 |
SMILES:
O=C1C=COC(C)=C1O
Aroma Description:
sweet, caramellic, cotton_candy, jammy, fruity, bread, baked
| Receptor | Expr.% | Agonist? | Dock Score | Known agonist | Correlated Perceptual Qualities |
|---|
Dock Score is a measure of how strongly the algorithm thinks the odorant is likely to be an agonist of the receptor.
Receptors in italics are "orphans", i.e. receptors whose agonists have not been identified experimentally.
1.) The Good Scents Company
2.) Guenhael Sanz, Claire Schlegel, Jean-Claude Pernollet and Loic Briand Comparison of Odorant Specificity of Two Human Olfactory Receptors from Different Phylogenetic Classes and Evidence for Antagonism Chemical Senses vol. 30 no. 1 (2005) doi:10.1093/chemse/bji002
3.) Huang, J., Lam, H., Koziol-White, C., Limjunyawong, N., Kim, D., Kim, N., ... & An, S. S. (2020). The odorant receptor OR2W3 on airway smooth muscle evokes bronchodilation via a cooperative chemosensory tradeoff between TMEM16A and CFTR. Proceedings of the National Academy of Sciences, 117(45), 28485-28495.
4.) Ashti Baghaei, K. (2015). Large scale analysis of olfactory receptors with highly genetically variations in relation with specific anosmia (Doctoral dissertation, Bochum, Ruhr-Universität Bochum, Diss., 2013).
5.) Roger Emter, Christel Merillat, Fiona Buchli, Felix Flachsmann, Andreas Natsch. Decoding human olfaction by high heterologous expression of odorant receptors detecting signature odorants. Current Biology, October 10, 2025