☰

Olfactory Receptor family 5 subfamily I member 1.

Estimated Expression: 46% of the population.

Expression estimate based on data from Verbeurgt et al (2014).

Sequence:

        10         20         30         40         50         60         70         80         90        100 
MEFTDRNYTL VTEFILLGFP TRPELQIVLF LMFLTLYAII LIGNIGLMLL IRIDPHLQTP MYFFLSNLSF VDLCYFSDIV PKMLVNFLSE NKSISYYGCA 

       110        120        130        140        150        160        170        180        190        200 
LQFYFFCTFA DTESFILAAM AYDRYVAICN PLLYTVVMSR GICMRLIVLS YLGGNMSSLV HTSFAFILKY CDKNVINHFF CDLPPLLKLS CTDTTINEWL 

       210        220        230        240        250        260        270        280        290        300 
LSTYGSSVEI ICFIIIIISY FFILLSVLKI RSFSGRKKTF STCASHLTSV TIYQGTLLFI YSRPSYLYSP NTDKIISVFY TIFIPVLNPL IYSLRNKDVK 

       310        320 
DAAEKVLRSK VDSS

Transmembrane Helices:

  TMR7     TMR6     TMR5     TMR4     TMR3     TMR2     TMR1   

T N P S     P R   I T T D     A F   I S K N      L F  L E P R  
 I K D   S Y I F   W E N   S T H V   Y Y S    N V L    V I Q   
F V S I   L L T   T S L L   L S S   L A C G  M K P V  M L F L  
 I T Y   G Q Y I   S G Y   M N G G   Y F Q    I D S    T L F   
V P I F   T V S   I E V S   L Y S   T C F F  F Y C L  I A Y L  
 P N L   T L H S   F C I   L V I L   D A F    D V F    I L I   
    I L   A C T   I I I I   R M C   F S E T  S L N S  G I N G  
         S F T K   Y S I   I G R S   A L I    L F F    L M L   
          K R G   L I F F           Y A M A  Y M P T  I R I L  
         S F S R   V S L             Y R D                 D   
                    I K L           C I A V                    
    

    UniProt | I-TASSER | AlphaFold | HORDE | GeneCards | ORDB
Odorant EC50 Adjusted Top Antagonist? Docks Aroma Notes
octanal - 1.9231 1   aldehydic, citrus, fatty, green, orange, peel, waxy
acetic acid - 0 1   sharp, pungent, sour, vinegar
2-aminoacetophenone - 0 1   grape, sweet, musty
androstenone - 0 1   animal, musky
para-anisaldehyde - 0 1   sweet, powdery, mimosa, floral, hawthorn, balsamic, vanilla, anise, woody, coumarinic, creamy, spicy
benzaldehyde - 0 1   sharp, sweet, bitter, almond, cherry
2-butanone - 0 1   acetone, ethereal, fruity, camphorous, chemical, green
calone - 0 1   fresh, watery, clean, melon, green, marine, ozone, phenolic
caproic acid - 0 1   cheesy, fatty, sour, sweaty
cedramber - 0 1   woody, dry, cedar, ambergris, earthy, vetiver
cinnamyl alcohol - 0 1   balsamic, cinnamon, cinnamyl, fermented, floral, green, hyacinth, powdery, spicy, sweet
civetone - 0 1   clean, musk, dry, animal, sweet
beta-damascone - 0 1   berry, currant, floral, fruity, honey, plum, rose, tobacco
exaltolide - 0 1   animal, fruity, musk, natural, powdery
geosmin - 0 1   earthy, fresh, musty, soil
geraniol - 0 1   citrus, floral, fruity, rose, sweet, waxy
globanone - 0 1   animal, balsamic, cloth, dry, floral, laundered, musk, tobacco, waxy
habanolide - 0 1   animal, cloth, dry, laundered, metallic, musk, powdery, sweet, tropical, waxy
hedione - 0 1   floral, oily, jasmine, green, lactonic, tropical, natural, sweet, fruity, citrus, lemon, grapefruit, woody
heptanal - 0 2   aldehydic, cognac, fatty, fresh, green, herbal, ozone
hexanal - 0 1   aldehydic, fatty, fresh, fruity, grass, green, leafy, sweaty
hexanol - 0 1   ethereal, fusel, oily, fruity, alcoholic, sweet, green, pungent, apple_skin
hydrocinnamaldehyde - 0 1   fresh, cortex, green, leafy, foliage, balsamic, storax, aldehydic, floral, melon
isobutyraldehyde - 0 1   cereal, malty
isovaleric acid - 0 1   cheesy, sour, sweaty, tropical
maltol - 0 1   sweet, caramellic, cotton_candy, jammy, fruity, bread, baked
4-methylvaleric acid - 0 1   cheesy, pungent
muguet propanol - 0 1   floral, lily_of_the_valley, woody
muscone - 0 1   musk, animal, powdery
gamma-nonalactone - 0 1   buttery, coconut, creamy, oily, sweet, waxy
1-octen-3-one - 0 1   earthy, metallic, mushroom
propionic acid - 0 1   acidic, cheesy, pungent, vinegar
sandranol - 0 1   woody, sandalwood, greasy, oily, waxy
timberol - 0 1   dry, sawdust, woody, powdery, amber, sandalwood
2,4,6-trichloroanisole - 0 1   cork_taint
ysamber K - 0 1   dry, woody, vetiver, amber, powdery, musk, fruity

1.) Ashti Baghaei, K. (2015). Large scale analysis of olfactory receptors with highly genetically variations in relation with specific anosmia (Doctoral dissertation, Bochum, Ruhr-Universität Bochum, Diss., 2013).

2.) Lim J. H., J. Park, E. H. Oh, H. J. Ko, S. Hong, and Park, T. H. (2014) Nanovesicle-based bioelectronic nose for the diagnosis of lung cancer from human blood. Adv. Healthcare Mater., 3: 360–366.

×
 
 

Code version:
 

Docker used:
 

Files:
Active model: text 3D download
Inactive model: text 3D download
Active dock: text 3D download
Inactive dock: text 3D download
JSON entry: text   download