Names:
3-methyl-2-hexenoic acid
SMILES:
CCCC(=CC(=O)[O-])C
Aroma Description:
cheesy, fruity1
| Receptor | Expression | log10 EC50 | Adj. Top | Antagonist? | Correlated Perceptual Qualities |
|---|---|---|---|---|---|
| OR51B2 | 100 | -4.4 3, -4.7 4 | 10 3, 10 4, (agonist) 6 | civet, cheesy, sour, honey, rancid | |
| OR51I2 | 100 | -4.52 4, -4.42 5 | 5 4, 8.3 5 | cheesy, sour, sweaty, sharp, acidic | |
| OR52K1 | 92 | - | (agonist) 6 | ||
| OR1A1 | 73 | -3.92 4 | 4.6 4 | citrus, waxy, rose, herbal, fresh, sweet, orange, caraway, fatty, spearmint | |
| OR2W1 | 53 | -4.22 4 | 0.8 4 | sweet, fatty, hay, alliaceous, tart, cinnamon, coumarinic, coconut, orange | |
| OR2J1 | ? | -4.53 2 | 0.0573 2 | hay, tonka, sweet, coumarinic | |
| OR51E1 | 100 | -4.22 4 | 0.48 4 | cheesy, sour, sweaty, acidic, sharp | |
| OR10A6 | 100 | -3.92 4 | 0.76 4 | peach, coconut, lactonic, sweet |
SMILES:
CCCC(=CC(=O)[O-])C
Aroma Description:
cheesy, fruity
| Receptor | Expr.% | Agonist? | Dock Score | Known agonist | Correlated Perceptual Qualities |
|---|
Dock Score is a measure of how strongly the algorithm thinks the odorant is likely to be an agonist of the receptor.
Receptors in italics are "orphans", i.e. receptors whose agonists have not been identified experimentally.
1.) The Good Scents Company
2.) Mainland JD, Li YR, Zhou T, Liu WL, Matsunami H. Human olfactory receptor responses to odorants. Sci Data. 2015 Feb 3;2:150002. doi: 10.1038/sdata.2015.2. PMID: 25977809; PMCID: PMC4412152.
3.) Li B, Kamarck ML, Peng Q, Lim FL, Keller A, et al. (2022) From musk to body odor: Decoding olfaction through genetic variation. PLOS Genetics 18(2): e1009564. https://doi.org/10.1371/journal.pgen.1009564
4.) Aya Kato, Naoko Saito (2018) Search method for odor control agent JP6422665B2
5.) Chatelain Pierre, Veithen Alex, Olfactory Receptors involved in the perception of sweat carboxylic acids and the use thereof. WO 2014/191047
6.) Roger EmterAndreas Natsch Modified olfactory receptors WO2024126820A1