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Olfactory Receptor family 51 subfamily I member 2.

Sequence:

        10         20         30         40         50         60         70         80         90        100 
MGLFNVTHPA FFLLTGIPGL ESSHSWLSGP LCVMYAVALG GNTVILQAVR VEPSLHEPMY YFLSMLSFSD VAISMATLPT VLRTFCLNAR NITFDACLIQ 

       110        120        130        140        150        160        170        180        190        200 
MFLIHFFSMM ESGILLAMSF DRYVAICDPL RYATVLTTEV IAAMGLGAAA RSFITLFPLP FLIKRLPICR SNVLSHSYCL HPDMMRLACA DISINSIYGL 

       210        220        230        240        250        260        270        280        290        300 
FVLVSTFGMD LFFIFLSYVL ILRSVMATAS REERLKALNT CVSHILAVLA FYVPMIGVST VHRFGKHVPC YIHVLMSNVY LFVPPVLNPL IYSAKTKEIR 

       310        320 
RAIFRMFHHI KI

Transmembrane Helices:

  TMR1     TMR2     TMR3     TMR4     TMR5     TMR6     TMR7   

S E L G      C F  A D F T       L   I S I D       V   I Y C P  
 S H S    T R L    I L C   F P L P   I S N   T S V G   L V H   
G S L W  V T P L  L F M Q   F L T   F L G Y   I M P   V N S M  
 C L P    T A M    F H I   I F S R   V L V   V Y F A   F L Y   
A Y M V  S I A V  M M S F   A A A   G F T S   L V A   V P P V  
 L A V    D S F    G S E   G L G M   L D M   L I H S   P N L   
T N G G  S L M S  A L L I   A A I   F I F F   V C T   S Y I L  
 L I V    L F Y    F S M   V E T T   Y S L   N L A K     K A   
R V A Q  Y M P E  V Y R D           L I L V   L R E            
                   C I A             V S R   E R S A           
                        D               A M                    
    

    UniProt | I-TASSER | AlphaFold | HORDE | GeneCards | ORDB
Odorant EC50 Adjusted Top Antagonist? Aroma Notes
benzoic acid -4.33 1 10 1  balsamic, urine
isovaleric acid -4.4 2 9.0909 2  cheesy, sour, sweaty, tropical
3-methyl-2-hexenoic acid -4.52 3 8.3 1  cheesy, fruity
valeric acid -4.07 1 7.8 1  acidic, cheesy, fruity, milky, sharp, sour, tobacco
caproic acid -4.4 2 6 1  cheesy, fatty, sour, sweaty
3-methylhexanoic acid -3.08 1 7.6 1  
butyric acid -3.61 1 6.1 1  sharp, acetic, cheesy, buttery, fruity, dairy, creamy
2-methylhexanoic acid -3.41 1 3 1  fruity, cheesy, oily, fatty, lard, acidic, chicken, chicken_fat, roasted, savory
delta-decalactone - 2.5 4  coconut, creamy, dairy, fatty, fresh, fruity, lactonic, milky, oily, peach, sweet
diacetyl - 0 4  buttery, caramellic, creamy, pungent, sweet
cuminaldehyde - -0.9091 2  spicy, cumin, green, herbal
cyclamal - -0.9091 2  cyclamen, floral, fresh, green, musty, rhubarb
hydroxycitronellal - -0.9091 2  floral, green, lily, melon, sweet, tropical, waxy
lilial - -0.9091 2  floral, muguet, watery, green, powdery, cumin
bourgeonal - -1.8182 2  fresh, watery, floral, cyclamen, sweet
florhydral - -1.8182 2  floral, green, muguet, linden_flower, lily_of_the_valley, fresh

1.) Chatelain Pierre, Veithen Alex, Olfactory Receptors involved in the perception of sweat carboxylic acids and the use thereof. WO 2014/191047

2.) Aya Kato, Naoko Saito, Etsuji Wakisaka (2016) Method for searching for malodor control agent, malodor control agent, and malodor control method. US9526680B2

3.) Aya Kato, Naoko Saito (2018) Search method for odor control agent JP6422665B2

4.) Geithe, C.; Andersen, G.; Malki, A.; Krautwurst, D. A butter aroma recombinate activates human class-I odorant receptors. J. Agric. Food Chem. 2015, 63, 9410–9420.
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