Olfactory Receptor family 10 subfamily C member 1.
Sequence:
10 20 30 40 50 60 70 80 90 100 MSANTSMVTE FLLLGFSHLA DLQGLLFSVF LTIYLLTVAG NFLIVVLVST DAALQSPMYF FLRTLSALEI GYTSVTVPLL LHHLLTGRRH ISRSGCALQM 110 120 130 140 150 160 170 180 190 200 FFFLFFGATE CCLLAAMAYD RYAAICEPLR YPLLLSHRVC LQLAGSAWAC GVLVGLGHTP FIFSLPFCGP NTIPQFFCEI QPVLQLVCGD TSLNELQIIL 210 220 230 240 250 260 270 280 290 300 ATALLILCPF GLILGSYGRI LVTIFRIPSV AGRRKAFSTC SSHLIMVSLF YGTALFIYIR PKASYDPATD PLVSLFYAVV TPILNPIIYS LRNTEVKAAL 310 320 KRTIQKTVPM EI
Transmembrane Helices:
TMR1 TMR2 TMR3 TMR4 TMR5 TMR6 TMR7 L D A L L G S R S F L S T D Y I F T A P D L G Q H H L L A C P T H G L E N L A T L P D V S F L L L P V F F M Q L G V L I I Q G Y F L F L S V T L F T V S F L F L V G C A T A S V M V A Y L L Y I T Y G I T A G F A W A L I L L I L H S I P T V A V T E L A C C E S G A L F P C S C T P N L L F N G S L T R A A L L Q L C L I L G S F A K S Y I I V V I L F F Y A M V R H S Y S G R R G L S V L Y M P S A Y R D L I R G A V S P C I A I T V E R F UniProt | I-TASSER | AlphaFold | HORDE | GeneCards | ORDB 2
| Odorant | EC50 | Adjusted Top | Antagonist? | Aroma Notes |
|---|---|---|---|---|
| amyl laurate | -3.81 1 | 1.4234 1 | fatty, oily, waxy | |
| 2-butanone | - | 1.9231 2 | acetone, ethereal, fruity, camphoreous, chemical, green | |
| hedione | - | 1.9231 2 | floral, oily, jasmine, green, lactonic, tropical, natural, sweet, fruity, citrus, lemon, grapefruit, woody | |
| heptanal | - | 0 3 | aldehydic, cognac, fatty, fresh, green, herbal, ozone |
1.) Mainland JD, Li YR, Zhou T, Liu WL, Matsunami H. Human olfactory receptor responses to odorants. Sci Data. 2015 Feb 3;2:150002. doi: 10.1038/sdata.2015.2. PMID: 25977809; PMCID: PMC4412152.
2.) Ashti Baghaei, K. (2015). Large scale analysis of olfactory receptors with highly genetically variations in relation with specific anosmia (Doctoral dissertation, Bochum, Ruhr-Universität Bochum, Diss., 2013).
3.) Lim J. H., J. Park, E. H. Oh, H. J. Ko, S. Hong, and Park, T. H. (2014) Nanovesicle-based bioelectronic nose for the diagnosis of lung cancer from human blood. Adv. Healthcare Mater., 3: 360–366.