☰

Olfactory Receptor family 11 subfamily H member 12.

Estimated Expression: 92% of the population.

Expression estimate based on data from Verbeurgt et al (2014).

Sequence:

        10         20         30         40         50         60         70         80         90        100 
MCPLTLQVTG LMNVSEPNSS FAFVNEFILQ GFTCEWTIQI FLFSLFTTTY ALTITGNGAI AFVLWCDWRL HTPMYMFLGN FSFLEIWYVS STVPKMLVNF 

       110        120        130        140        150        160        170        180        190        200 
LSEKKNISFA GCFLQFYFFF SLGTSECLLL TVMAFDQYLA ICRPLLYPNI MTGHLCAKLV ILCWVCGFLW FLIPIVLISQ MPFCGPNIID HVVCDPGPRF 

       210        220        230        240        250        260        270        280        290        300 
ALDCVSAPRI QLFCYTLSSL VIFGNFLFII GSYTLVLKAV LGMPSSTGRH KAFSTCGSHL AVVSLCYSSL MVMYVSPGLG HSTGMQKIET LFYAMVTPLF 

       310        320        330 
NPLIYSLQNK EIKAALRKVL GSSNII

Transmembrane Helices:

  TMR7     TMR6     TMR5     TMR4     TMR3     TMR2     TMR1   

M G T S       S   R P A S     I L   I N K K      L F  I T W E  
 I K Q   V Y M V   L Q I   V I P I   A F S    N V L    F I Q   
F L T E   M L S   T Y C F   L F W   L F C G  M K P V  L S F L  
 M A Y   S Y C L   S S L   L F G C   Y F Q    T S S    T T F   
L P T V   S V V   F I V L   V W C   S F F F  V Y W I  L A Y T  
 P N F   A L H S   F N G   L I V L   T G L    E L F    T I T   
  Y I L   G C T   I I F L   K A C   L C E S  S F N G  A G N G  
         S F A K   Y S G   L H G T   T L L    L F M    F A I   
          H R G   L V L T           F A M V  Y M P T  C W L V  
         T S S P   V A K             Y Q D                 D   
                    M G L           C I A L                    
    

    UniProt | I-TASSER | AlphaFold | HORDE | GeneCards
Odorant EC50 Adjusted Top Antagonist? Aroma Notes
(R)-(-)-carvone -4.7 1 10 1  herbal, minty, spearmint, sweet
acetophenone -5.4 1 7.8947 1  sweet, pungent, hawthorn, mimosa, almond, acacia, chemical
coumarin -4.1 1 7.8947 1  coumarinic, hay, sweet, tonka

1.) Xiaojing Cong, Wenwen Ren, Jody Pacalon, Claire A. de March, Lun Xu, Hiroaki Matsunami, Yiqun Yu, Jérôme Golebiowski Functions of olfactory receptors are decoded from their sequence https://doi.org/10.1101/2020.01.06.895540
×
 
 

Code version:
 

Docker used:
 

Files:
Active model: text 3D download
Inactive model: text 3D download
Active dock: text 3D download
Inactive dock: text 3D download
JSON entry: text   download