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Olfactory Receptor family 11 subfamily H member 4.

Sequence:

        10         20         30         40         50         60         70         80         90        100 
MSFFFVDLRP MNRSATHIVT EFILLGFPGC WKIQIFLFSL FLVIYVLTLL GNGAIIYAVR CNPLLHTPMY FLLGNFAFLE IWYVSSTIPN MLVNILSKTK 

       110        120        130        140        150        160        170        180        190        200 
AISFSGCFLQ FYFFFSLGTT ECLFLAVMAY DRYLAICHPL QYPAIMTVRF CGKLVSFCWL IGFLGYPIPI FYISQLPFCG PNIIDHFLCD MDPLMALSCA 

       210        220        230        240        250        260        270        280        290        300 
PAPITECIFY TQSSLVLFFT SMYILRSYIL LLTAVFQVPS AAGRRKAFST CGSHLVVVSL FYGTVMVMYV SPTYGIPTLL QKILTLVYSV TTPLFNPLIY 

       310        320        330 
TLRNKDMKLA LRNVLFGMRI RQNS

Transmembrane Helices:

  TMR1     TMR2     TMR3     TMR4     TMR5     TMR6     TMR7   

K W C G        I  G S F S       Y   I P A P  V Y M V  L L T P  
 I Q I    N V L    L F C   F I P I   C E T    M V T    I K Q   
S F L F  M N P I  F Y F Q   P Y G   T Y F I  G Y F L  V L T L  
 L F L    T S S    S F F   L F G I   S S Q    S V V    V S Y   
V Y I V  V Y W I  T T G L   L W C   F L V L  V L H S  L P T T  
 L T L    E L F    L C E   F S V L   S T F    G C T    P N F   
G N G L  A F N G  V A L F   K G C   L I Y M  S F A K    Y I L  
 I I A    L L F    Y A M   F R V T   Y S R    R R G            
R V A Y  Y M P T  L Y R D           L L L I  A A S P           
                   C I A             V A T                     
                        H               Q F                    
    

    UniProt | I-TASSER | AlphaFold | HORDE | GeneCards | ORDB
Odorant EC50 Adjusted Top Antagonist? Aroma Notes
phenethyl alcohol -5.69 1 -  floral, rose, dried_rose, sweet, fresh, bready, honey
phenylpropyl alcohol -5.28 1 -  sweet, spicy, cinnamyl, floral, hyacinth, balsamic, cinnamon, fruity, honey, winey
isovaleric acid -3.87 2 6 3  cheesy, sour, sweaty, tropical
benzyl acetone - 0 1  floral, balsamic, strawberry
benzyl alcohol - 0 1  floral, rose, phenolic, balsamic
cinnamyl alcohol - 0 1  balsamic, cinnamon, cinnamyl, fermented, floral, green, hyacinth, powdery, spicy, sweet
(S)-(-)-citronellol - 0 1  citrus, fatty, floral, fruity, green, leathery, rose, sweet, terpenic, waxy
cyclamal - 0 1  cyclamen, floral, fresh, green, musty, rhubarb
alpha-damascone - 0 1  floral, rose, apple, fruity, black_currant, sweet, green, berry
geraniol - 0 1  citrus, floral, fruity, rose, sweet, waxy
(Z)-3-hexen-1-ol - 0 1  fresh, green, grassy, foliage, vegetable, herbal, oily, melon_rind, pungent, lettuce
alpha-ionone - 0 1  sweet, woody, floral, violet, orris, tropical, fruity
beta-ionone - 0 1  beeswax, berry, floral, fruity, sweet, tropical, woody, fragrant, sour, acid, vinegar, sharp, pungent
lavandulol - 0 1  floral, waxy, mimosa, herbal
linalool - 0 1  blueberry, bois_de_rose, citrus, floral, green, rose, sweet, woody
lyral - 0 1  aquatic, clean, cyclamen, floral, muguet, rhubarb, watery, waxy, woody
melafleur - 0 1  floral, clean, muguet, ozone, marine, sandy, balsamic
nerol - 0 1  citrus, floral, fresh, green, lemon, lime, magnolia, natural, neroli, spicy, sweet, waxy
nonadecane - 0 1  bland

1.) Duroux R, Mandeau A, Guiraudie-Capraz G, Quesnel Y, Loing E. A Rose Extract Protects the Skin against Stress Mediators: A Potential Role of Olfactory Receptors. Molecules. 2020 Oct 16;25(20):4743. doi: 10.3390/molecules25204743. PMID: 33081083; PMCID: PMC7587601.

2.) Mainland JD, Li YR, Zhou T, Liu WL, Matsunami H. Human olfactory receptor responses to odorants. Sci Data. 2015 Feb 3;2:150002. doi: 10.1038/sdata.2015.2. PMID: 25977809; PMCID: PMC4412152.

3.) I. Menashe, T. Abaffy, Y. Hasin, S. Goshen, V. Yahalom, C.W. Luetje, D. Lancet, Genetic Elucidation of Human Hyperosmia to Isovaleric Acid, PLoS Biol. 5 (2007) e284.

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