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Olfactory Receptor family 2 subfamily F member 1.

Estimated Expression: 100% of the population.

Expression estimate based on data from Verbeurgt et al (2014).

Sequence:

        10         20         30         40         50         60         70         80         90        100 
MGTDNQTWVS EFILLGLSSD WDTRVSLFVL FLVMYVVTVL GNCLIVLLIR LDSRLHTPMY FFLTNLSLVD VSYATSVVPQ LLAHFLAEHK AIPFQSCAAQ 

       110        120        130        140        150        160        170        180        190        200 
LFFSLALGGI EFVLLAVMAY DRYVAVCDAL RYSAIMHGGL CARLAITSWV SGFISSPVQT AITFQLPMCR NKFIDHISCE LLAVVRLACV DTSSNEVTIM 

       210        220        230        240        250        260        270        280        290        300 
VSSIVLLMTP FCLVLLSYIQ IISTILKIQS REGRKKAFHT CASHLTVVAL CYGVAIFTYI QPHSSPSVLQ EKLFSVFYAI LTPMLNPMIY SLRNKEVKGA 

       310        320 
WQKLLWKFSG LTSKLAT

Transmembrane Helices:

  TMR7     TMR6     TMR5     TMR4     TMR3     TMR2     TMR1   


E Q L V       S   S S T D     T I   P I A K      L F  T D W D  
 F L K   S H P Q   V E N   A T Q V   S Q F    H A L    S V R   
Y F V S   I Y T   V M I T   P S S   Q A A C  L Q P V  L V F L  
 L I A   F I A V   I S S   I F G S   F F L    V S T    V L F   
L M P T   G Y C   M L L V   V W S   L A L S  A Y S V  V V Y M  
 M P N   L A V V   F P T   T I A L   I G G    D V L    L V T   
    Y I   T L H   L V L C   R A C   L V F E  S L N T  L C N G  
         S A C T   Y S L   L G G H   V A L    L F F    L V I   
          H F A   I I Q I           D Y A M  Y M P T  L R I L  
         K K R G   I T S             V Y R                 D   
                    I K L           D C V A                    
    

    UniProt | I-TASSER | AlphaFold | HORDE | GeneCards | ORDB
Odorant EC50 Adjusted Top Antagonist? Aroma Notes
thioglycolic acid -8.13 1 0.1244 1  sulfurous
cyclohexanone -7.97 1 0.0298 1  acetone, minty
geranyl acetate -3.59 1 0.9378 1  floral, rose, lavender, green, waxy, herbal, cooling, oily, soapy, citrus, winey, rummy
eugenyl acetate -3 1 (agonist) 1  carnation, clove, floral, fresh, malty, spicy, sweet, woody
n-amyl acetate -1.62 1 0.0318 1  banana, fruity, solvent, sweet, apple, ethereal, pear

1.) Mainland JD, Li YR, Zhou T, Liu WL, Matsunami H. Human olfactory receptor responses to odorants. Sci Data. 2015 Feb 3;2:150002. doi: 10.1038/sdata.2015.2. PMID: 25977809; PMCID: PMC4412152.
 2.53 3.29 3.32 3.33 3.36 3.37 3.40 3.41 4.53 4.56 4.57 4.60 45.49 45.51 45.52 45.53 5.39 5.42 5.43 5.46 5.47 6.48 6.51 6.55 6.59 7.38 7.39 7.41 7.42
OR2F1Y L S L G G F V G S S Q S E L L I S S L L Y A Y H S V Y A
OR2F2Y L S L G G F V G N S Q S E L L I S S L L Y T Y H S V Y A
OR13C8Y M S F G A C M G D S Q V E I L M S N V L Y I Y E S L Y G
OR2K2Y M S L G S C V G T A E T E I L M V S L L Y A Y S S L Y G
OR13D1Y M S L G S C V G T S Q T E I L M T N S L Y A Y K G L Y G
OR2B3Y L F L G A C L G N S Q F E V P L F S I L Y A Y P S L Y G
OR13J1Y M S L G S C L C K S E T K I L L G S L L Y I Y K T V Y A
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