SMILES:
C1CCC(=O)CC1
Aroma Description:
acetone, minty1
| Receptor | log10 EC50 | Adj. Top | Antagonist? | Correlated Perceptual Qualities |
|---|---|---|---|---|
| OR2J2 | -5 6 | - | tart, carnation, orange, warm, hay, clove, cinnamon, sweet | |
| OR2F1 | -7.97 2 | 0.0298 2 | acetone, carnation, malty | |
| OR2Y1 | -3.14 7 | - | spearmint, minty, acetone | |
| OR52D1 | - | 3.1472 3 | anise, cheesy, orange, sweet, dairy, sour, rancid, waxy, tart, sharp | |
| OR1G1 | - | 0.6091 3 | Y | waxy, tart, orange, sweet, aldehydic, fresh, citrus, clean, medicinal, anise |
| OR5AN1 | - | 0.0004 5 | musk, animal, powdery | |
| OR10J5 | - | 0 4 | ||
| OR1A1 | - | 0 4, 0 5 | ||
| OR2C1 | - | 0 4 | ||
| OR2W1 | - | 0 4 | ||
| OR51E1 | - | 0 4 | ||
| OR51L1 | - | 0 4 | ||
| OR5P3 | - | 0 4 | ||
| OR2J3 | - | 0 5 |
SMILES:
C1CCC(=O)CC1
Aroma Description:
acetone, minty
| Receptor | Dock Score | Affinity | A100 | Correlated Perceptual Qualities |
|---|
Dock Score: This is a measure of whether the algorithm thinks the odorant is an agonist of the receptor.
Affinity: The binding affinity, in kJ/mol, of the ligand docked in the active or inactive model, whichever is greater.
A100: A measure of the degree of activation of the receptor. See
Ibrahim et al (2019).
1.) The Good Scents Company
2.) Mainland JD, Li YR, Zhou T, Liu WL, Matsunami H. Human olfactory receptor responses to odorants. Sci Data. 2015 Feb 3;2:150002. doi: 10.1038/sdata.2015.2. PMID: 25977809; PMCID: PMC4412152.
3.) Guenhael Sanz, Claire Schlegel, Jean-Claude Pernollet and Loic Briand Comparison of Odorant Specificity of Two Human Olfactory Receptors from Different Phylogenetic Classes and Evidence for Antagonism Chemical Senses vol. 30 no. 1 (2005) doi:10.1093/chemse/bji002
4.) Saito H, Chi Q, Zhuang H, Matsunami H, Mainland JD. Odor coding by a Mammalian receptor repertoire. Sci Signal. 2009 Mar 3;2(60):ra9. doi: 10.1126/scisignal.2000016. PMID: 19261596; PMCID: PMC2774247.
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6.) Dunkel, A.; Steinhaus, M.; Kotthoff, M.; Nowak, B.; Krautwurst, D.; Schieberle, P.; Hofmann, T. Nature’s chemical signatures in human olfaction: A foodborne perspective for future biotechnology. Angew. Chem. Int. Ed. Engl. 2014, 53, 7124–7143.
7.) Huiwen Ren, Ruijing Zhang, Haibo Zhang, Che Bian. Ecnomotopic olfactory receptors in metabolic regulation. Biomedicine & Pharmacotherapy 179 (2024) 117403