SMILES:
CC(=O)OCCC1=CC=CC=C1
Aroma Description:
floral, fruity, honey, rose, sweet, tropical1
| Receptor | log10 EC50 | Adj. Top | Antagonist? | Hypothesized PQ | Associated Perceptual Qualities (PQs) |
|---|---|---|---|---|---|
| OR2W1 | -5.1 3, -5.82 6 | 1.9444 6 | allyl-demimetallic7 |
herbal, fatty, sweet, tart, banana, mushroom, orange, fresh, rancid, cherry, acacia, orangeflower | |
| OR10A6 | -5.46 6 | 10 6 | bland-fatty | floral, cinnamyl, cyclamen, rhubarb, neroli, hyacinth, dirty, balsamic, cinnamon, honey, muguet, rose | |
| OR1A1 | -4.56 3 | - | leafy7 |
caraway, herbal, orange, cognac, weedy, spearmint, mushroom, hay, licorice, fatty | |
| OR2AG1 | - | 7.9787 2 | stemmy7 |
pepper, honey, galbanum, solvent, heliotrope, banana | |
| OR1D2 | -3.91 4 | - | clean-bright7 |
rose, peach, bois_de_rose, lactonic, fresh, citrus, floral, coconut, waxy, creamy, blueberry, clean, ketonic, lime | |
| OR5A1 | - | 0 5 | |||
| OR5A2 | - | 0 5 | |||
| OR5AN1 | - | 0 5 |
1.) The Good Scents Company
2.) Gelis L, Wolf S, Hatt H, Neuhaus EM, Gerwert K. Prediction of a ligand-binding niche within a human olfactory receptor by combining site-directed mutagenesis with dynamic homology modeling. Angew Chem Int Ed Engl. 2012 Jan 27;51(5):1274-8. doi: 10.1002/anie.201103980. Epub 2011 Dec 5. PMID: 22144177.
3.) Christiane Geithe, Franziska Noe, Johanna Kreissl, Dietmar Krautwurst, The Broadly Tuned Odorant Receptor OR1A1 is Highly Selective for 3-Methyl-2,4-nonanedione, a Key Food Odorant in Aged Wines, Tea, and Other Foods, Chemical Senses, Volume 42, Issue 3, 1 March 2017, Pages 181–193, https://doi.org/10.1093/chemse/bjw117
4.) Veithen, A.; Wilin, F.; Philippeau, M.; Chatelain, P. OR1D2 is a broadly tuned human olfactory receptor. Chem. Senses 2015, 40, 262–263.
5.) Keiichi Yoshikawa, Jun Deguchi, Hu Jieying et al. Diverse yet selective tuning of an odorant receptor for sensing four classes of musk compounds, 03 August 2022, PREPRINT (Version 1) available at Research Square [https://doi.org/10.21203/rs.3.rs-1916850/v1]
6.) Saito N, Yamano E, Ishii A, Tanaka M, Nakamura J, et al. (2018) Involvement of the olfactory system in the induction of anti-fatigue effects by odorants. PLOS ONE 13(3): e0195263. https://doi.org/10.1371/journal.pone.0195263
7.) PrimaryOdors.org differential experiment.
References for aroma perceptual qualities should not be taken to indicate that the authors of outside studies necessarily assigned aroma notes to the neurons that receive input from any given receptor. Rather, the findings of outside studies often constitute the information on which we base our own perceptual quality assignments.