Olfactory Receptor family 5 subfamily A member 2.
Sequence:
10 20 30 40 50 60 70 80 90 100 MAVGRNNTIV TKFILLGLSD HPQMKIFLFM LFLGLYLLTL AWNLSLIALI KMDSHLHMPM YFFLSNLSFL DICYVSSTAP KMLSDIITEQ KTISFVGCAT 110 120 130 140 150 160 170 180 190 200 QYFVFCGMGL TECFLLAAMA YDRYAAICNP LLYTVLISHT LCLKMVVGAY VGGFLSSFIE TYSVYQHDFC GPYMINHFFC DLPPVLALSC SDTFTSEVVT 210 220 230 240 250 260 270 280 290 300 FIVSVVVGIV SVLVVLISYG YIVAAVVKIS SATGRTKAFS TCASHLTAVT LFYGSGFFMY MRPSSSYSLN RDKVVSIFYA LVIPVVNPII YSFRNKEIKN 310 320 330 AMRKAMERDP GISHGGPFIF MTLG
Transmembrane Helices:
TMR1 TMR2 TMR3 TMR4 TMR5 TMR6 TMR7 M Q P H I G V F S S T F T D R R N L S F I K D S L T A C Y T E I V E S M Y M F V K D L M F L M K P A V F Y Q F S S I F T V F G S F I S V G L F T S S G C F L F G G V S V G Y F L L A Y L L Y L V Y C I T L G M V Y A I G V V T V A V P I V A L T D L F F C E G V V M V S V T L H S P N V S L N W S L N S A A L L K L C L V V L A C T S Y I I A I L L F F Y A M L T H S Y S I S F A K F K I L Y M P M A Y R D V I Y G T R G C I A V A A T A S S N K V UniProt | I-TASSER | AlphaFold | HORDE | GeneCards
Odorant | EC50 | Adjusted Top | Antagonist? | Aroma Notes |
---|---|---|---|---|
beta-ionone | -3.5 1 | 10 1 | beeswax, berry, floral, fruity, sweet, tropical, woody, fragrant, sour, acid, vinegar, sharp, pungent | |
habanolide | - | 4.2 2 | animal, cloth, dry, laundered, metallic, musk, powdery, sweet, tropical, waxy | |
tonalide | - | 3.3 2 | amber, ambrette, fruity, musk, powdery, sweet | |
celestolide | - | 2.9 2 | ambergris, animal, cedar, musk, woody | |
civetone | - | 2.5 2 | animal, clean, dry, musk, sweet | |
ethylene brassylate | - | 2.5 2 | ambrette, floral, musk, powdery, sweet, woody | |
exaltolide | - | 2.4 2 | musk, animal, powdery, natural, fruity | |
galaxolide | - | 2.2 2 | floral, musk, sweet | |
musk xylene | - | 2.2 2 | dry, fatty, musk, soapy, sweet | |
cyclopentadecanol | - | 2 2 | musk | |
globanone | - | 2 2 | animal, balsamic, cloth, dry, floral, laundered, musk, tobacco, waxy | |
musk ketone | - | 2 2 | dry, fatty, floral, musk, powdery, soapy | |
ambrettolide | - | 1.7 2 | amber, berry, fruity, musk, soapy, sweet | |
cyclopentadecanone | - | 1.3 2 | animal, greasy, musk, natural, powdery | |
muscone | - | 1.1 2 | animal, fatty, musk, natural, powdery, sweet | |
muscenone | - | 1 2 | animal, musk, soapy | |
romandolide | - | 1 2 | musk, ambrette, fruity, berry | |
amber xtreme | - | 0.5 2 | animal, musk, woody, spicy | |
cosmone | - | 0.5 2 | ambergris, animal, anisic, cloth, fatty, laundered, musk, powdery, woody | |
helvetolide | - | 0.2 2 | ambrette, floral, fruity, musk, pear, woody | |
omega-dodecanolactam | - | 0.1 2 | ||
acetic acid | - | 0 2 | acrid, sharp, vinegar | |
acetophenone | - | 0 2 | sweet, pungent, hawthorn, mimosa, almond, acacia, chemical | |
amber butanol | - | 0 2 | woody, amber, ambrette | |
amberketal | - | 0 2 | dry, amber, powdery, woody, musk | |
ambrinol | - | 0 2 | amber, natural, musk, animal | |
ambroxide | - | 0 2 | amber, ambergris, cedar, dry, green, musk, paper, pine, seedy, woody | |
benzoic acid | - | 0 2 | balsamic, urine | |
benzyl propionate | - | 0 2 | apple, balsamic, banana, floral, fruity, jammy, jasmine, sweet | |
boisambrene | - | 0 2 | woody, cedar, ambergris, dry, dusty, amber | |
borneol | - | 0 2 | camphoraceous, peppery, pine, woody | |
p-t-butyl cyclohexanone | - | 0 2 | woody, minty, patchouli, musk, leathery | |
calone | - | 0 2 | fresh, watery, clean, melon, green, marine, ozone, phenolic | |
camphene | - | 0 2 | woody, herbal, fir_needle | |
camphor | - | 0 2 | camphoraceous | |
caproic acid | - | 0 2 | cheesy, fatty, sour, sweaty | |
caprylic acid | - | 0 2 | cheesy, fatty, oily, rancid, vegetable, waxy | |
(R)-(-)-carvone | - | 0 2 | herbal, minty, spearmint, sweet | |
1,4-cineol | - | 0 2 | cooling, pine, minty, camphoraceous, terpenic, green | |
claritone | - | 0 2 | sweet, herbal, clary_sage, sage, bergamot, petitgrain, tropical, citrus | |
p-cresyl phenyl acetate | - | 0 2 | animal, rose, honey, narcissus, lily, hyacinth | |
cyclododecanone | - | 0 2 | ||
cyclopentadecane | - | 0 2 | ||
beta-damascone | - | 0 2 | berry, currant, floral, fruity, honey, plum, rose, tobacco | |
gamma-decalactone | - | 0 2 | buttery, coconut, fresh, oily, peach, sweet, waxy | |
1-decanol | - | 0 2 | aldehydic, clean, fatty, floral, green, orange, sweet, tart, watery, waxy | |
delta-dodecalactone | - | 0 2 | buttery, coconut, fresh, metallic, oily, peach, sweet | |
1-dodecanol | - | 0 2 | aldehydic, coconut, earthy, fatty, honey, soapy, waxy | |
fructone | - | 0 2 | apple, fruity, green, plum, sweet, tropical, woody | |
geraniol | - | 0 2 | citrus, floral, fruity, rose, sweet, waxy | |
1-hexanol | - | 0 2 | alcoholic, ethereal, fruity, fusel, green, herbal, oily, pungent, sweet | |
cis-3-hexen-1-ol | - | 0 2 | foliage, fresh, grassy, green, herbal, oily, vegetable | |
cis-3-hexenyl hexanoate | - | 0 2 | fruity, green, waxy, pear, winey, tropical, grassy, pineapple | |
Iso-E-Super | - | 0 2 | ambergris, cedar, dry, ketonic, old_wood, phenolic, woody | |
isoamyl butyrate | - | 0 2 | fruity, green, apricot, pear, banana | |
isoborneol | - | 0 2 | balsamic, camphoraceous, herbal, woody | |
isobornyl acetate | - | 0 2 | balsamic, camphoraceous, citrus, herbal, soapy, sweet, woody | |
isolongifolanone | - | 0 2 | dry, woody, patchouli, cedar, earthy, tobacco, incense | |
isomenthone | - | 0 2 | minty, cooling, peppermint, sweet | |
isovaleric acid | - | 0 2 | cheesy, sour, sweaty, tropical | |
jasmolactone delta | - | 0 2 | oily, fruity, coconut, floral, petal, jasmine, tuberose, peach, apricot | |
d-limonene | - | 0 2 | citrus, fresh, orange, sweet | |
(-)-menthol | - | 0 2 | cooling, mentholic, minty, peppermint | |
methyl cinnamate | - | 0 2 | balsamic, cherry, strawberry, sweet | |
6-methyl quinoline | - | 0 2 | leathery, tonka, castoreum, tobacco, civet, fecal | |
gamma-nonalactone | - | 0 2 | buttery, coconut, creamy, oily, sweet, waxy | |
gamma-octalactone | - | 0 2 | coconut, creamy, dairy, fatty, sweet, tonka, waxy | |
1-octanol | - | 0 2 | aldehydic, green, mushroom, orange, rose, waxy | |
oranger crystals | - | 0 2 | honey, neroli, orangeflower, powdery, sweet | |
orris hexanone | - | 0 2 | woody, dry, orris, earthy, camphoraceous | |
2-pentadecanone | - | 0 2 | burnt, celery, fatty, fresh, jasmine, oily, waxy | |
8-pentadecanone | - | 0 2 | ||
phenethyl acetate | - | 0 2 | floral, fruity, honey, rose, sweet, tropical | |
phenylacetic acid | - | 0 2 | sweet, honey, floral, honeysuckle, sour, waxy, civet | |
piperonyl acetone | - | 0 2 | berry, candy, cotton, floral, fruity, heliotrope, jammy, powdery, raspberry, sweet | |
raspberry ketone | - | 0 2 | berry, floral, jammy, raspberry, ripe, seedy, sweet, woody | |
santaliff | - | 0 2 | sandalwood, creamy, woody, milky, waxy, greasy, musk | |
(R)-(+)-sclareolide | - | 0 2 | dry, paper, woody, ambergris, labdanum | |
styralyl acetate | - | 0 2 | green, leafy, gardenia, rhubarb, musty | |
sulcatone | - | 0 2 | apple, banana, cheesy, citrus, creamy, fruity, green, ketonic, lemongrass, musty | |
alpha-terpinene | - | 0 2 | woody, terpenic, lemon, herbal, medicinal, citrus | |
tonka undecanone | - | 0 2 | sweet, spicy, balsamic, tonka, woody, tobacco, green | |
gamma-undecalactone | - | 0 2 | apricot, coconut, creamy, fatty, fruity, ketonic, lactonic, peach | |
valeric acid | - | 0 2 | acidic, cheesy, fruity, milky, sharp, sour, tobacco | |
gamma-valerolactone | - | 0 2 | cocoa, herbal, sweet, tobacco, warm, woody | |
woody cyclohexanone | - | 0 2 | woody, old_wood, amber, tobacco, herbal | |
ysamber | - | 0 2 | dry, woody, vetiver, amber, powdery, musk, fruity |
1.) S.R. Jaeger, J.F. McRae, C.M. Bava, M.K. Beresford, D. Hunter, Y. Jia, S.L. Chheang, D. Jin, M. Peng, J.C. Gamble et al, A Mendelian Trait for Olfactory Sensitivity Affects Odor Experience and Food Selection, Curr. Biol. 23 (2013) 1601-1605.
2.) Keiichi Yoshikawa, Jun Deguchi, Hu Jieying et al. Diverse yet selective tuning of an odorant receptor for sensing four classes of musk compounds, 03 August 2022, PREPRINT (Version 1) available at Research Square [https://doi.org/10.21203/rs.3.rs-1916850/v1]