☰

Olfactory Receptor family 2 subfamily M member 4.

Sequence:

        10         20         30         40         50         60         70         80         90        100 
MVWENQTFNS IFILLGIFNH SPTHTFLFSL VLGIFSLALM ENISMVLLIY IEKQLHTPMY FLLSQLSLMD LMLICTTLPK MIFSYLSGKK SISLAGCGTQ 

       110        120        130        140        150        160        170        180        190        200 
IFFYVSLLGA ECFLLAVMAY DRYVAICHPL QYTILMNPKL CVFMTVASWT LGSLDGIIVL AAVLSFSYCS SLEIHHFFCD VAALLPLSCT ETSAFERLLV 

       210        220        230        240        250        260        270        280        290        300 
ICCVVMLIFP VSVIILSYSH VLRAVIHMGS GESRRKAFTT CSSHLSVVGL YYGAAMFMYM RPASKHTPDQ DKMVSAFYTI LTPMLNPLIY SLRNKEVFRA 

       310        320 
LQKVLKKRKL I

Transmembrane Helices:

  TMR1     TMR2     TMR3     TMR4     TMR5     TMR6     TMR7   

T P S H     F I   G A L S     V A   A S T E     P R   Q D P T  
 F T H   M K P L   T G C   A L V I   R E F   M Y M F   M K D   
L S F L   T T C   F F I Q   I G D   I V L L   M A A   F A S V  
 G L V   I L M L   S V Y   L S G L   V C C   G Y Y L   I T Y   
L S F I   D M L   A G L L   T W S   I L M V   G V V   M P T L  
 M L A   S L Q S   F C E   A V T M   V P F   S L H S   P N L   
S I N E   L L F   V A L L   F V C   I I V S   S C T   S Y I L  
 L V M   Y M P T   Y A M   L K P N   Y S L   T F A K       L   
  Y I L           V Y R D           L V H S   R R S            
                   C I A             V A R   E G S G           
                        H               H I                    
    

    UniProt | I-TASSER | AlphaFold | HORDE | GeneCards
Odorant EC50 Adjusted Top Antagonist? Aroma Notes
estragole -5.7 1 9.5 1  anise, anisic, fennel, green, herbal, sassafrass, spicy, sweet
cresyl methyl ether -4.8 1 10 1  naphthyl, narcissus, nutty, powdery, ylang
cinnamaldehyde -4 1 -  sweet, spicy, candy, cinnamon, warm
nerolidol -4 1 -  citrus, floral, green, waxy, woody
alpha-damascone -4.8 1 4.7 1  apple, currant, floral, fruity, rose
fructone -4 1 5 1  apple, fruity, green, plum, sweet, tropical, woody
vanillin -3.4 1 5.5 1  chocolate, creamy, sweet, vanilla

1.) D. Gonzalez-Kristeller, J.B.P. do Nascimento, P.A.F. Galante, B. Malnic, Identification of agonists for a group of human odorant receptors, Front. Pharmacol. 6 (2015)