☰

Olfactory Receptor family 52 subfamily E member 8.

Sequence:

        10         20         30         40         50         60         70         80         90        100 
MAGRMSTSNH TQFHPSSFLL LGIPGLEDVH IWIGVPFFFV YLVALLGNTA LLFVIQTEQS LHEPMYYFLA MLDSIDLGLS TATIPKMLGI FWFNTKEISF 

       110        120        130        140        150        160        170        180        190        200 
GGCLSHMFFI HFFTAMESIV LVAMAFDRYI AICKPLRYTM ILTSKIISLI AGIAVLRSLY MVVPLVFLLL RLPFCGHRII PHTYCEHMGI ARLACASIKV 

       210        220        230        240        250        260        270        280        290        300 
NIRFGLGNIS LLLLDVILII LSYVRILYAV FCLPSWEARL KALNTCGSHI GVILAFFTPA FFSFLTHRFG HNIPQYIHII LANLYVVVPP ALNPVIYGVR 

       310        320 
TKQIRERVLR IFLKTNH

Transmembrane Helices:

  TMR1     TMR2     TMR3     TMR4     TMR5     TMR6     TMR7   

D E L G   I G L   G G F S       L   V K I S       T   I Y Q P  
 I H V   M K P I   S L C   F V L P   R I N   L F S F   I I H   
V G I W   T A T   F F M H   V V M   G L G F   F A P   L N A L  
 F F P   S L G L   F H I   Y L S R   S I N   T F F A   V V Y   
L Y V F   D I S   M A T F   L V A   L L L L   L I V   A P P V  
 L A V   D L M A   I S E   I G A I   I V D   G I H S   P N L   
T N G L   L F Y   A V L V   L S I   L I I L   G C T   G Y I V  
 L L A   Y M P E   F A M   I K S T   V Y S   N L A K     R V   
Q I V F           I Y R D           Y L I R   L R A            
                   C I A             F V A   E W S P           
                        K                 C                    
    

    UniProt | I-TASSER | AlphaFold | HORDE | GeneCards
Odorant EC50 Adjusted Top Antagonist? Aroma Notes
butyric acid - 0 1  acetic, buttery, cheesy, fruity, sharp
delta-decalactone - 0 1  coconut, creamy, dairy, fatty, fresh, fruity, lactonic, milky, oily, peach, sweet
diacetyl - 0 1  buttery, caramellic, creamy, pungent, sweet

1.) Geithe, C.; Andersen, G.; Malki, A.; Krautwurst, D. A butter aroma recombinate activates human class-I odorant receptors. J. Agric. Food Chem. 2015, 63, 9410–9420.