Aroma Description:
animal, fatty, musk, natural, powdery, sweet1

Receptor log10 EC50 Adj. Top Antagonist? Hypothesized PQ Associated Perceptual Qualities (PQs)
OR5AN1 -5.49 3, -6.54 6 9.1045 2, 10 3, 3.6 4, 4.7 5, 9.2857 6  musky3
musk, powdery, animal
OR4K2 - 1.3462 7  plushy storax, natural, clove, animal, malty, cortex, musk, foliage, cherry, almond, sharp, powdery
OR5A2 - 1.1 5  musky5
musk, animal
OR10Q1 - 0.1923 7    natural, orangeflower, powdery, neroli, animal, musk
OR1A1 - 0 4     
OR2J3 - 0 4     
OR5A1 - 0 5     
OR4P4 - 0 7     
OR5I1 - 0 7     
OR10G4 - 0 9     
OR9Q2 - 0 9     
OR8D1 - -0.2538 8     
OR5K1 - -13.0435 10     

1.) The Good Scents Company

2.) Ahmed, Lucky et al "Molecular mechanism of activation of human musk receptors OR5AN1 and OR1A1 by (R)-muscone and diverse other musk-smelling compounds." Proceedings of the National Academy of Sciences 115.17 (2018): E3950-E3958. Web. 29 Aug. 2021.

3.) M. Shirasu, K. Yoshikawa, Y. Takai, A. Nakashima, H. Takeuchi, H. Sakano, K. Touhara, Olfactory receptor and neural pathway responsible for highly selective sensing of musk odors, Neuron 81 (2014) 165-178.

4.) Ligand Specificity and Evolution of Mammalian Musk Odor Receptors: Effect of Single Receptor Deletion on Odor Detection Narumi Sato-Akuhara, Nao Horio, Aya Kato-Namba, Keiichi Yoshikawa, Yoshihito Niimura, Sayoko Ihara, Mika Shirasu, Kazushige Touhara Journal of Neuroscience 20 April 2016, 36 (16) 4482-4491; DOI: 10.1523/JNEUROSCI.3259-15.2016

5.) Keiichi Yoshikawa, Jun Deguchi, Hu Jieying et al. Diverse yet selective tuning of an odorant receptor for sensing four classes of musk compounds, 03 August 2022, PREPRINT (Version 1) available at Research Square []

6.) Omura M, Takabatake Y, Lempert E, Benjamin-Hong S, D'Hulst C, Feinstein P. A genetic platform for functionally profiling odorant receptors in olfactory cilia ex vivo. Sci Signal. 2022 Aug 9;15(746):eabm6112. doi: 10.1126/scisignal.abm6112. Epub 2022 Aug 9. PMID: 35944068.

7.) Ashti Baghaei, K. (2015). Large scale analysis of olfactory receptors with highly genetically variations in relation with specific anosmia (Doctoral dissertation, Bochum, Ruhr-Universit├Ąt Bochum, Diss., 2013).

8.) Aya NAMBA, Naoko Saito, Michiaki Inoue, Tsuyoshi TOYABE (2016) Inhibitor of odor caused by sotolone US9254248B2

9.) Keiichi Yoshikawa, Naoko Saito (2016) Method for selecting odor-controlling substance EP3305898B1

10.) Aya Namba, Naoko Saito, Michiaki Inoue, Go Toriyabe (2018) Search method of odor control agent by furaneol JP6276555B2

References for aroma perceptual qualities should not be taken to indicate that the authors of outside studies necessarily assigned aroma notes to the neurons that receive input from any given receptor. Rather, the findings of outside studies often constitute the information on which we base our own perceptual quality assignments.