Olfactory Receptor family 10 subfamily Q member 1.
Estimated Expression: 100% of the population.
Expression estimate based on data from Verbeurgt et al (2014).
Sequence:
10 20 30 40 50 60 70 80 90 100 MPVGKLVFNQ SEPTEFVFRA FTTATEFQVL LFLLFLLLYL MILCGNTAII WVVCTHSTLR TPMYFFLSNL SFLELCYTTV VVPLMLSNIL GAQKPISLAG 110 120 130 140 150 160 170 180 190 200 CGAQMFFFVT LGSTDCFLLA IMAYDRYVAI CHPLHYTLIM TRELCTQMLG GALGLALFPS LQLTALIFTL PFCGHHQEIN HFLCDVPPVL RLACADIRVH 210 220 230 240 250 260 270 280 290 300 QAVLYVVSIL VLTIPFLLIC VSYVFITCAI LSIRSAEGRR RAFSTCSFHL TVVLLQYGCC SLVYLRPRSS TSEDEDSQIA LVYTFVTPLL NPLLYSLRNK 310 320 DVKGALRSAI IRKAASDAN
Transmembrane Helices:
TMR7 TMR6 TMR5 TMR4 TMR3 TMR2 TMR1 D E D E P V R I D I L S I P K L I F E T A I Q S R L Y V A Q H A T L Q G A L N S L L V Q Y V L A L S C V Y L V L S P Q A G C M L P V L L F L V F T C G Y Q I S V F L A L F F M V V T L L F L L P T L L V T L V L G L A L T V F T Y C L M L Y L L P N V T L H F P I G G L M T S G E L F C L I S Y L F S C C I L L Q T C L F C D S L N S A T N G T S F A Y S V L E R T I A L L F F W I I R R R T I F V D Y A M Y M P T T C V V G E A S I A C V Y R H I S L H C I A UniProt | I-TASSER | AlphaFold | HORDE | GeneCards | ORDB
| Odorant | EC50 | Adjusted Top | Antagonist? | Aroma Notes |
|---|---|---|---|---|
| exaltolide | -4.96 1 | 10 1 | animal, fruity, musk, natural, powdery | |
| oranger crystals | -4.2 2 | 2.3529 2 | sweet, neroli, orangeflower, powdery, honey, floral, orange, naphthyl, citrus | |
| civetone | - | 0.1923 1 | clean, musk, dry, animal, sweet | |
| muscone | - | 0.1923 1 | musk, animal, powdery |
1.) Ashti Baghaei, K. (2015). Large scale analysis of olfactory receptors with highly genetically variations in relation with specific anosmia (Doctoral dissertation, Bochum, Ruhr-Universität Bochum, Diss., 2013).
2.) Ieki T, Yamanaka Y, Yoshikawa K (2022) Functional analysis of human olfactory receptors with a high basal activity using LNCaP cell line. PLOS ONE 17(4): e0267356.
| Prot. | Sim. | Expr. | 2.53 | 3.29 | 3.32 | 3.33 | 3.36 | 3.37 | 3.40 | 3.41 | 4.53 | 4.56 | 4.57 | 4.60 | 45.49 | 45.51 | 45.52 | 45.53 | 5.39 | 5.42 | 5.43 | 5.46 | 5.47 | 6.48 | 6.51 | 6.55 | 6.59 | 7.38 | 7.39 | 7.41 | 7.42 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| OR10Q1 | 100 | 100% | Y | M | F | V | G | S | C | F | A | P | S | L | L | D | V | P | L | V | S | V | L | Y | C | Y | R | A | L | Y | T |
| OR10W1 | 89 | 100% | Y | M | F | I | G | S | C | F | G | L | S | L | F | D | V | P | V | A | A | A | I | Y | C | Y | S | S | L | Y | T |
| OR10T2 | 88 | 65% | Y | L | F | L | A | C | C | L | G | I | A | A | F | D | M | A | L | L | S | V | I | Y | A | Y | K | A | V | Y | T |
| OR10V1 | 87 | 76% | Y | M | F | V | G | G | C | V | G | L | S | L | Y | D | M | P | L | I | S | V | L | Y | T | Y | S | S | V | Y | T |
| OR10AC1 | 87 | Y | M | F | V | G | G | C | F | G | V | S | L | F | D | I | T | L | A | C | L | L | Y | A | Y | R | A | L | Y | T | |
| OR2H2 | 84 | 88% | F | I | F | L | G | T | C | I | G | E | S | Q | V | E | V | P | V | A | S | I | L | Y | V | Y | K | G | L | Y | A |
| OR10A7 | 83 | 15% | F | M | F | F | G | S | C | F | G | V | S | Q | F | D | G | P | A | S | T | F | I | Y | A | Y | K | S | L | Y | T |
| OR2Y1 | 82 | 73% | F | L | Y | L | G | S | C | V | G | N | S | Q | F | E | M | P | M | A | R | V | V | Y | A | Y | I | A | L | Y | T |
| OR10Z1 | 82 | 96% | Y | M | S | A | A | C | C | F | G | F | G | M | F | D | T | P | I | L | S | V | L | Y | A | Y | K | A | M | Y | T |
| OR10X1 | 82 | 38% | Y | M | F | L | G | G | C | I | G | I | S | E | F | H | M | L | I | I | S | G | L | F | A | Y | E | A | V | Y | T |
| OR11A1 | 82 | 100% | Y | F | F | G | A | T | C | L | G | V | D | V | Y | D | F | M | T | L | S | C | L | Y | L | Y | S | S | L | Y | T |
| OR2J1 | 82 | Y | L | V | L | G | T | C | V | G | T | S | H | F | E | V | P | L | M | S | F | V | F | V | Y | P | A | L | Y | T | |
| OR10K2 | 82 | 96% | Y | M | F | L | G | C | S | F | G | V | A | I | F | D | I | A | I | L | C | V | L | Y | A | Y | Q | S | V | Y | T |
| OR11H6 | 81 | 96% | Y | F | F | F | G | T | C | F | G | C | Y | P | V | D | P | G | C | F | N | I | I | Y | L | Y | T | T | L | Y | T |
| OR11L1 | 81 | 100% | Y | L | F | V | G | A | C | F | G | T | G | P | F | D | L | P | I | L | S | V | L | Y | M | Y | S | S | V | Y | T |
| OR11G2 | 81 | 80% | Y | F | F | F | G | S | C | F | G | W | F | P | L | D | P | A | F | L | S | P | V | Y | V | Y | P | T | L | Y | S |
| OR2W3 | 81 | 100% | F | L | F | L | G | G | C | L | G | N | S | M | L | E | M | P | V | L | A | V | V | Y | I | Y | G | M | L | Y | N |
| OR2D3 | 80 | 100% | F | I | F | L | G | C | C | A | G | V | S | D | F | E | P | P | I | M | G | I | L | Y | G | Y | N | S | V | Y | T |
| OR2J2 | 80 | 92% | H | L | V | L | G | I | C | V | G | I | S | H | F | E | V | P | L | M | S | F | V | F | V | Y | P | A | L | Y | T |
| OR2G3 | 80 | 80% | F | L | S | L | G | S | C | I | G | S | S | H | I | E | V | P | L | V | S | F | V | Y | I | Y | S | S | L | Y | T |
| OR5AU1 | 80 | 100% | Y | M | Y | A | A | T | C | Y | G | N | S | H | F | D | G | P | L | F | A | N | L | F | T | Y | R | A | V | Y | T |