Olfactory Receptor family 2 subfamily Y member 1.
Sequence:
10 20 30 40 50 60 70 80 90 100 MGSFNTSFED GFILVGFSDW PQLEPILFVF IFIFYSLTLF GNTIIIALSW LDLRLHTPMY FFLSHLSLLD LCFTTSTVPQ LLINLCGVDR TITRGGCVAQ 110 120 130 140 150 160 170 180 190 200 LFIYLALGST ECVLLVVMAF DRYAAVCRPL HYMAIMHPHL CQTLAIASWG AGFVNSLIQT GLAMAMPLCG HRLNHFFCEM PVFLKLACAD TEGTEAKMFV 210 220 230 240 250 260 270 280 290 300 ARVIVVAVPA ALILGSYVHI AHAVLRVKST AGRRKAFGTC GSHLLVVFLF YGSAIYTYLQ SIHNYSEREG KFVALFYTII TPILNPLIYT LRNKDVKGAL 310 320 WKVLWRGRDS G
Transmembrane Helices:
TMR1 TMR2 TMR3 TMR4 TMR5 TMR6 TMR7 L Q P W C L G G R T A L G E T D Q E R E S I P E N I L A V C G T Q I A E T L Y T Y F K G F V F L L Q P V I F L Q L S N V F M K I A S F L A V I F I T S T A L Y V F G A V R A G Y F L I T Y L S Y F T F C L T S G L G W S A V V I F V V I P T I F L T D L L V C E A I A L A P V L L H S P N L I T N G S L H S V V L L T Q C L I L A G C T T Y I L A I I L F F F A M L H P H Y S G G F A K R L W S L Y M P T A Y R D A I H V R R G C V A V A H A T S K R R L UniProt | I-TASSER | AlphaFold | HORDE | GeneCards | ORDB
Odorant | EC50 | Adjusted Top | Antagonist? | Aroma Notes |
---|---|---|---|---|
(R)-(-)-carvone | -5.81 1 | - | herbal, minty, spearmint, sweet | |
cyclohexanone | -3.14 2 | - | acetone, minty |
1.) Dunkel, A.; Steinhaus, M.; Kotthoff, M.; Nowak, B.; Krautwurst, D.; Schieberle, P.; Hofmann, T. Nature’s chemical signatures in human olfaction: A foodborne perspective for future biotechnology. Angew. Chem. Int. Ed. Engl. 2014, 53, 7124–7143.
2.) Huiwen Ren, Ruijing Zhang, Haibo Zhang, Che Bian. Ecnomotopic olfactory receptors in metabolic regulation. Biomedicine & Pharmacotherapy 179 (2024) 117403