☰

Olfactory Receptor family 13 subfamily C member 2.

Estimated Expression: 100% of the population.

Expression estimate based on data from Verbeurgt et al (2014).

Sequence:

        10         20         30         40         50         60         70         80         90        100 
MEWENHTILV EFFLKGLSGH PRLELLFFVL IFIMYVVILL GNGTLILISI LDPHLHTPMY FFLGNLSFLD ICYTTTSIPS TLVSFLSERK TISLSGCAVQ 

       110        120        130        140        150        160        170        180        190        200 
MFLGLAMGTT ECVLLGMMAF DRYVAICNPL RYPIIMSKDA YVPMAAGSWI IGAVNSAVQS VFVVQLPFCR NNIINHFTCE ILAVMKLACA DISDNEFIML 

       210        220        230        240        250        260        270        280        290        300 
VATTLFILTP LLLIIVSYTL IIVSIFKISS SEGRSKASST CSAHLTVVII FYGTILFMYM KPKSKETLNS DDLDATDKII SMFYGVMTPM MNPLIYSLRN 

       310        320 
KDVKEAVKHL LNRRFFSK

Transmembrane Helices:

  TMR7     TMR6     TMR5     TMR4     TMR3     TMR2     TMR1   


S N L T       P   D S I D     V F   S I T K      L F  L R P H  
 L D D   K M Y M   F E N   V S Q V   G S L    S V L    L L E   
D T A D   F L I   V L M I   A S N   Q V A C  T S P I  L V F F  
 I I K   T G Y F   T T A   V A G I   L F M    S T T    I F I   
Y F M S   I I V   L I F L   I W S   M A L G  T Y C I  V V Y M  
 M V G   V T L H   L P T   G A A M   T T G    D L F    L L I   
M M P T   A S C   I I L L   P V Y   L V C E  S L N G  T G N G  
 L P N   T S S A   Y S V   A D K S   M G L    L F F    L I L   
    Y I   K S R   I I L T           D F A M  Y M P T  L I S I  
         G E S S   I S V             V Y R                 D   
                    I K F           N C I A                    
    

    UniProt | I-TASSER | AlphaFold | HORDE | GeneCards | ORDB
Odorant EC50 Adjusted Top Antagonist? Aroma Notes
para-anisaldehyde -3.6 1 1.7647 1  sweet, powdery, mimosa, floral, hawthorn, balsamic, vanilla, anise, woody, coumarinic, creamy, spicy
heptanal - 0 2  aldehydic, cognac, fatty, fresh, green, herbal, ozone

1.) Ieki T, Yamanaka Y, Yoshikawa K (2022) Functional analysis of human olfactory receptors with a high basal activity using LNCaP cell line. PLOS ONE 17(4): e0267356.

2.) Lim J. H., J. Park, E. H. Oh, H. J. Ko, S. Hong, and Park, T. H. (2014) Nanovesicle-based bioelectronic nose for the diagnosis of lung cancer from human blood. Adv. Healthcare Mater., 3: 360–366.

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