Olfactory Receptor family 2 subfamily G member 2.
Sequence:
10 20 30 40 50 60 70 80 90 100 MGMVRHTNES NLAGFILLGF SDYPQLQKVL FVLILILYLL TILGNTTIIL VSRLEPKLHM PMYFFLSHLS FLYRCFTSSV IPQLLVNLWE PMKTIAYGGC 110 120 130 140 150 160 170 180 190 200 LVHLYNSHAL GSTECVLPAV MSCDRYVAVC RPLHYTVLMH IHLCMALASM AWLSGIATTL VQSTLTLQLP FCGHRQVDHF ICEVPVLIKL ACVGTTFNEA 210 220 230 240 250 260 270 280 290 300 ELFVASILFL IVPVSFILVS SGYIAHAVLR IKSATRRQKA FGTCFSHLTV VTIFYGTIIF MYLQPAKSRS RDQGKFVSLF YTVVTRMLNP LIYTLRIKEV 310 320 KGALKKVLAK ALGVNIL
Transmembrane Helices:
TMR1 TMR2 TMR3 TMR4 TMR5 TMR6 TMR7 L Q P Y N V L G G Y A T L F T T G Q Q D R S V K Q L Q P I V L C T S Q V A E N L Y M F F K G L V F L V S S N Y L H L T T V F L E I I T F L S V I L I T F C R A H S A I G S I S A G Y F I V T Y L L Y L Y L F T S G L L W A I L F L T V V M R T V L I T S L H S V C E M S A L V P V T L H S P N L T T N G L F F V A P L A M C L I F S F C T T Y I L L I I Y M P M C S M L H I H S S V G F A K L R S V V Y R D A I Y G Q R R C V A V A H T A S K R R L UniProt | I-TASSER | AlphaFold | HORDE | GeneCards | ORDB
Odorant | EC50 | Adjusted Top | Antagonist? | Aroma Notes |
---|---|---|---|---|
alpha-damascone | -4.8 1 | 6.5 1 | floral, rose, apple, fruity, black_currant, sweet, green, berry | |
maltyl isobutyrate | -5.8 1 | 4 1 | berry, caramellic, cotton_candy, fruity, strawberry, sweet, tropical | |
vanillin | -4.6 1 | 5.5 1 | chocolate, creamy, sweet, vanilla | |
cinnamaldehyde | -4 1 | - | sweet, spicy, candy, cinnamon, warm | |
2-decenal | -2.62 2 | 0.2467 2 | waxy, fatty, earthy, green, cilantro, mushroom, aldehydic, fried, chicken_fat, tallow |
1.) D. Gonzalez-Kristeller, J.B.P. do Nascimento, P.A.F. Galante, B. Malnic, Identification of agonists for a group of human odorant receptors, Front. Pharmacol. 6 (2015)
2.) Mainland JD, Li YR, Zhou T, Liu WL, Matsunami H. Human olfactory receptor responses to odorants. Sci Data. 2015 Feb 3;2:150002. doi: 10.1038/sdata.2015.2. PMID: 25977809; PMCID: PMC4412152.