☰

Olfactory Receptor family 1 subfamily L member 3.

Estimated Expression: 100% of the population.

Expression estimate based on data from Verbeurgt et al (2014).

Sequence:

        10         20         30         40         50         60         70         80         90        100 
MGMSNLTRLS EFILLGLSSR SEDQRPLFAL FLIIYLVTLM GNLLIILAIH SDPRLQNPMY FFLSILSFAD ICYTTVIVPK MLVNFLSEKK TISYAECLAQ 

       110        120        130        140        150        160        170        180        190        200 
MYFFLVFGNI DSYLLAAMAI NRCVAICNPF HYVTVMNRRC CVLLLAFPIT FSYFHSLLHV LLVNRLTFCT SNVIHHFFCD VNPVLKLSCS STFVNEIVAM 

       210        220        230        240        250        260        270        280        290        300 
TEGLASVMAP FVCIIISYLR ILIAVLKIPS AAGKHKAFST CSSHLTVVIL FYGSISYVYL QPLSSYTVKD RIATINYTVL TSVLNPFIYS LRNKDMKRGL 

       310        320        330 
QKLINKIKSQ MSRFSTKTNK ICGP

Transmembrane Helices:

  TMR7     TMR6     TMR5     TMR4     TMR3     TMR2     TMR1   


A I R D       S   V F T S     V L   S I T K      L F  D E S R  
 N I T   S L P Q   I E N   L V H L   E A Y    N V L    P R Q   
L V T Y   L Y V   T M A V   L S H   Q A L C  M K P V  L A F L  
 V S T   Y S I S   L G E   F Y S F   F Y M    I V T    I L F   
F P N L   G Y F   M V S A   T I P   F V L F  T Y C I  V L Y I  
 S Y I   L I V V   F P A   F A L L   I N G    D A F    M L T   
      L   T L H   I I C V   L V C   L Y S D  S L I S  L L N G  
         S S C T   Y S I   C R R N   A A L    L F F    L I I   
          S F A   L I R L           N I A M  Y M P N  S H I A  
         K H K G   V A I             V C R                 D   
                    I K L           N C I A                    
    

    UniProt | I-TASSER | AlphaFold | HORDE | GeneCards | ORDB
Odorant EC50 Adjusted Top Antagonist? Aroma Notes
alpha-damascone -4.6 1 9 1  floral, rose, apple, fruity, black_currant, sweet, green, berry
vanillin -3.8 1 7.7 1  chocolate, creamy, sweet, vanilla

1.) D. Gonzalez-Kristeller, J.B.P. do Nascimento, P.A.F. Galante, B. Malnic, Identification of agonists for a group of human odorant receptors, Front. Pharmacol. 6 (2015)
Prot.Sim.Expr.2.53 3.29 3.32 3.33 3.36 3.37 3.40 3.41 4.53 4.56 4.57 4.60 45.49 45.51 45.52 45.53 5.39 5.42 5.43 5.46 5.47 6.48 6.51 6.55 6.59 7.38 7.39 7.41 7.42
OR1L3100 100%Y M F L G N S Y S H S H F D V N A E G S V Y I Y L T I Y T
OR1L188 100%Y M F L G N S Y P H S H F D D Q V E G V I Y I Y L T I Y T
OR1L684 100%F M F M G N S Y S H S R F D T Q V E T V I Y I Y L T V Y T
OR1L484 100%F M F M G N S Y S H S R F D T Q V E T V I Y V Y L T V Y T
OR1G183 61%F L F M V M A F N H S H F D I N I T G T G F S D P S V Y T
OR1L883F M L Y G N S C P H S H L D L S Q E A V L Y I Y P T I Y T
OR1C183 100%F L F V V N S L T H A H F D L N I V G L A Y A Y S T I Y S
OR1Q182 100%F T F I A V N F S H A H F D L Y I E G V I Y L Y L T V Y T
OR1F181 30%F M V F V D N F A N V H F D V T I E G V M Y I Y L T V Y T
OR7A580 100%V M F I A G N F S Y S Q F E L N I T V L G Y I Y S S V Y T
OR1K180 100%F M F F G V S C S H S Y F D H Q I E G V V Y V Y T T V Y T
OR7E2480 96%F M F V A C D M S D S H F D P S I M G F G Y G Y S S V Y T
×
 
 

Code version:
 

Docker used:
 

Files:
Active model: text 3D download
Inactive model: text 3D download
Active dock: text 3D download
Inactive dock: text 3D download
JSON entry: text   download