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Olfactory Receptor family 1 subfamily C member 1.

Sequence:

        10         20         30         40         50         60         70         80         90        100 
MEKRNLTVVR EFVLLGLPSS AEQQHLLSVL FLCMYLATTL GNMLIIATIG FDSHLHSPMY FFLSNLAFVD ICFTSTTVPQ MVVNILTGTK TISFAGCLTQ 

       110        120        130        140        150        160        170        180        190        200 
LFFFVSFVNM DSLLLCVMAY DRYVAICHPL HYTARMNLCL CVQLVAGLWL VTYLHALLHT VLIAQLSFCA SNIIHHFFCD LNPLLQLSCS DVSFNVMIIF 

       210        220        230        240        250        260        270        280        290        300 
AVGGLLALTP LVCILVSYGL IFSTVLKITS TQGKQRAVST CSCHLSVVVL FYGTAIAVYF SPSSPHMPES DTLSTIMYSM VAPMLNPFIY TLRNRDMKRG 

       310        320 
LQKMLLKCTV FQQQ

Transmembrane Helices:

  TMR1     TMR2     TMR3     TMR4     TMR5     TMR6     TMR7   

Q E A S        I  G A F S     I L   F S V D       S   S E P M  
 L H Q    N V V    T L C   V T H L   M V N   F Y V A   L T D   
L V S L  M Q P V  F F L Q   L A H   A F I I   I A T   M I T S  
 C L F    T T S    S V F   L Y T V   G G V   G Y F L   M S Y   
A L Y M  T F C I  M N V F   L W L   L A L L   V V V   M P A V  
 L T T    D V F    L S D   G A V L   L P T   S L H C   P N L   
L M N G  A L N S  V C L L   Q V C   L I C V   S C T   T Y I F  
 A I I    L F F    Y A M   L C L N   Y S V   S V A R       L   
  G I T  Y M P S  V Y R D           F I L G   Q K G            
                   C I A             V T S   Q T S T           
                        H               K L                    
    

    UniProt | I-TASSER | AlphaFold | HORDE | GeneCards | ORDB 2
Odorant EC50 Adjusted Top Antagonist? Aroma Notes
linalool -7.86 1 10 2  blueberry, bois_de_rose, citrus, floral, green, rose, sweet, woody
coumarin -6 1 2.6667 3  coumarinic, hay, sweet, tonka
pelargonic acid - 2.3333 3  cheesy, dairy, dirty, waxy
androstenone - 1 3  animal, musky
allyl phenylacetate - 0 3  honey, fruity, rummy
amyl hexanoate - 0 3  sweet, green, fruity, estery, pineapple, apple, pear, fatty, waxy, cognac, melon
l-arabinose - 0 3  
benzene - 0 3  
butyl formate - 0 3  fruity, plum, rummy, brandy
butyric acid - 0 3  sharp, acetic, cheesy, buttery, fruity, dairy, creamy
(S)-(+)-carvone - 0 3  bready, caraway, minty, spicy
citral - 0 3  sharp, lemon, sweet, fresh, juicy, lemon_peel, tart, green, citrus, lime, woody, herbal
coffee difuran - 0 3  cabbage, chicken, coffee, meaty, onion, roasted, sulfurous, cocoa, earthy, fungal, mild, mushroom, nutty
beta-damascone - 0 3  berry, currant, floral, fruity, honey, plum, rose, tobacco
decanal - 0 3  sweet, aldehydic, waxy, orange_peel, citrus, floral
dimethyl disulfide - 0 3  sulfurous, vegetable, cabbage, onion, malty, creamy
2,4-DNT - 0 3  
2-ethyl fenchol - 0 3  camphoraceous, earthy, humus, mushroom, musty, patchouli, potato, rooty, tea
ethyl vanillin - 0 3  sweet, creamy, vanilla, caramellic
eugenol - 0 3  clove, spicy, sweet, woody
eugenyl acetate - 0 3  carnation, clove, floral, fresh, malty, spicy, sweet, woody
helional - 0 3  cyclamen, fresh, green, hay, ozone, watery
2-heptanone - 0 3  banana, cheesy, coconut, creamy, fruity, green, herbal, ketonic, spicy, sweet, waxy, woody
(Z)-3-hexen-1-ol - 0 3  fresh, green, grassy, foliage, vegetable, herbal, oily, melon_rind, pungent, lettuce
isobutylamine - 0 3  cheesy, fishy
d-limonene - 0 3  citrus, orange, fresh, sweet
lyral - 0 3  aquatic, clean, cyclamen, floral, muguet, rhubarb, watery, waxy, woody
(1S,2R,5S)-(+)-menthol - 0 3  cooling, mentholic, minty
methyl eugenol - 0 3  carnation, cinnamon, clove, fresh, spicy, sweet, warm
methyl furfuryl disulfide - 0 3  sulfurous, coffee, roasted, alliaceous, meaty, liver, onion, garlic, eggy
methyl salicylate - 0 3  minty, wintergreen
nonanal - 0 3  waxy, aldehydic, rose, fresh, orris, orange_peel, fatty, peely
octanethiol - 0 3  sulfurous
1-octanol - 0 3  aldehydic, green, mushroom, orange, rose, waxy
octyl octanoate - 0 3  coconut, oily, fruity
pentanol - 0 3  fusel, oily, sweet, balsamic, pungent, fermented, bready, yeasty, winey, solvent
propanal - 0 3  alcoholic, cocoa, earthy, nutty, whiskey, winey
propionic acid - 0 3  acidic, cheesy, pungent, vinegar
pyrazine - 0 3  pungent, sweet, corn, roasted, hazelnut, barley
quinoline - 0 3  earthy, medicinal, musty, rubbery, tobacco
terpinyl acetate - 0 3  bergamot, citrus, herbal, lavender, lime

1.) Mainland JD, Li YR, Zhou T, Liu WL, Matsunami H. Human olfactory receptor responses to odorants. Sci Data. 2015 Feb 3;2:150002. doi: 10.1038/sdata.2015.2. PMID: 25977809; PMCID: PMC4412152.

2.) C. Trimmer, A. Keller, N. R. Murphy, L. L. Snyder, J. R. Willer, M. H. Nagai, N. Katsanis, L. B. Vosshall, H. Matsunami, and J. D. Mainland Genetic variation across the human olfactory receptor repertoire alters odor perception PNAS | May 7, 2019 | vol. 116 | no. 19 | 9475–9480

3.) Adipietro KA, Mainland JD, Matsunami H (2012) Functional Evolution of Mammalian Odorant Receptors. PLoS Genet 8(7): e1002821. doi:10.1371/ journal.pgen.1002821
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