Olfactory Receptor family 56 subfamily B member 4.
Estimated Expression: 96% of the population.
Expression estimate based on data from Verbeurgt et al (2014).
Sequence:
10 20 30 40 50 60 70 80 90 100 MDTSTSVTYD SSLQISQFIL MGLPGIHEWQ HWLSLPLTLL YLLALGANLL IIITIQHETV LHEPMYHLLG ILAVVDIGLA TTIMPKILAI FWFDAKAISL 110 120 130 140 150 160 170 180 190 200 PMCFAQIYAI HCFFCIESGI FLCMAVDRYI AICRPLQYPS IVTKAFVFKA TGFIMLRNGL LTIPVPILAA QRHYCSRNEI EHCLCSNLGV ISLACDDITV 210 220 230 240 250 260 270 280 290 300 NKFYQLMLAW VLVGSDMALV FSSYAVILHS VLRLNSAEAM SKALSTCSSH LILILFHTGI IVLSVTHLAE KKIPLIPVFL NVLHNVIPPA LNPLACALRM 310 320 HKLRLGFQRL LGLGQDVSK
Transmembrane Helices:
TMR7 TMR6 TMR5 TMR4 TMR3 TMR2 TMR1 I L P I L H V T I D A L S I A K W F W E H I F V P T V S L F K N I P V P M P L I A L W H Q L V N L V I I M L Q Y I T L Q A F C I K P M P L S L V N H G T H F W A L L G N R A Y I I T T L T L A P P I L I L G V L V L M I F C H I A L G I L L Y L P N L I L H S M D S F G T A I C F D V V G L A A L S C T F V L A K F V I G S E A L I G L L N A S L A K Y S S F A K T C L F L L H I I I S M A L I V A D V A M Y M P E H Q I T E A S N V S H I Y R E L R L C I A UniProt | I-TASSER | AlphaFold | HORDE | GeneCards | ORDB
| Odorant | EC50 | Adjusted Top | Antagonist? | Aroma Notes |
|---|---|---|---|---|
| delta-decalactone | - | 8.3333 1 | coconut, creamy, dairy, fatty, fresh, fruity, lactonic, milky, oily, peach, sweet | |
| butyric acid | - | 1.6667 1 | sharp, acetic, cheesy, buttery, fruity, dairy, creamy | |
| diacetyl | - | 0 1 | buttery, caramellic, creamy, pungent, sweet | |
| heptanal | - | 0 2 | aldehydic, cognac, fatty, fresh, green, herbal, ozone |
1.) Geithe, C.; Andersen, G.; Malki, A.; Krautwurst, D. A butter aroma recombinate activates human class-I odorant receptors. J. Agric. Food Chem. 2015, 63, 9410–9420.
2.) Lim J. H., J. Park, E. H. Oh, H. J. Ko, S. Hong, and Park, T. H. (2014) Nanovesicle-based bioelectronic nose for the diagnosis of lung cancer from human blood. Adv. Healthcare Mater., 3: 360–366.