Olfactory Receptor family 56 subfamily B member 4.
Sequence:
10 20 30 40 50 60 70 80 90 100 MDTSTSVTYD SSLQISQFIL MGLPGIHEWQ HWLSLPLTLL YLLALGANLL IIITIQHETV LHEPMYHLLG ILAVVDIGLA TTIMPKILAI FWFDAKAISL 110 120 130 140 150 160 170 180 190 200 PMCFAQIYAI HCFFCIESGI FLCMAVDRYI AICRPLQYPS IVTKAFVFKA TGFIMLRNGL LTIPVPILAA QRHYCSRNEI EHCLCSNLGV ISLACDDITV 210 220 230 240 250 260 270 280 290 300 NKFYQLMLAW VLVGSDMALV FSSYAVILHS VLRLNSAEAM SKALSTCSSH LILILFHTGI IVLSVTHLAE KKIPLIPVFL NVLHNVIPPA LNPLACALRM 310 320 HKLRLGFQRL LGLGQDVSK
Transmembrane Helices:
TMR1 TMR2 TMR3 TMR4 TMR5 TMR6 TMR7 E H I G I A L M P L S L V T I D L H I L P I H Q W I K P M A F C I P V P F K N T V S L F V P L S L W I T T A Y I Q I T L M L Q Y V I I L V N L T L P A L G I C H I L G N R W A L G T H F V N H L Y L L D V V I C F F L M I G V L V L I L A P P I L A L A L I G G S E F G T A M D S I L H S P N L L N A G L L H C L F I K F V F V L A S C T C A L I I L Y M P E V A M F A K T Y S S S L A K Q I T I I Y R D L I V A S M A C I A V S H E A S N R R L UniProt | I-TASSER | AlphaFold | HORDE | GeneCards | ORDB
| Odorant | EC50 | Adjusted Top | Antagonist? | Aroma Notes |
|---|---|---|---|---|
| delta-decalactone | - | 8.3333 1 | coconut, creamy, dairy, fatty, fresh, fruity, lactonic, milky, oily, peach, sweet | |
| butyric acid | - | 1.6667 1 | sharp, acetic, cheesy, buttery, fruity, dairy, creamy | |
| diacetyl | - | 0 1 | buttery, caramellic, creamy, pungent, sweet | |
| heptanal | - | 0 2 | aldehydic, cognac, fatty, fresh, green, herbal, ozone |
1.) Geithe, C.; Andersen, G.; Malki, A.; Krautwurst, D. A butter aroma recombinate activates human class-I odorant receptors. J. Agric. Food Chem. 2015, 63, 9410–9420.
2.) Lim J. H., J. Park, E. H. Oh, H. J. Ko, S. Hong, and Park, T. H. (2014) Nanovesicle-based bioelectronic nose for the diagnosis of lung cancer from human blood. Adv. Healthcare Mater., 3: 360–366.