Olfactory Receptor family 7 subfamily A member 10.
Estimated Expression: 73% of the population.
Expression estimate based on data from Verbeurgt et al (2014).
Sequence:
10 20 30 40 50 60 70 80 90 100 MKSWNNTIIL EFLLLGISEE PELQAFLFGL FLSMYLVTVL GNLLIILATI SDSHLHTPMY FFLSNLSFVD ICFVSTTVPK MLVNIQTHNK VITYAGCITQ 110 120 130 140 150 160 170 180 190 200 MCFFLLFVGL DNFLLTVMAY DRFVAICHPL HYMVIMNPQL CGLLVLASWI MSVLNSMLQS LMVLPLPFCT HMEIPHFFCE INQVVHLACS DTFLNDIVMY 210 220 230 240 250 260 270 280 290 300 FAVALLGGGP LTGILYSYSK IVSSIRAISS AQGKYKAFST CASHLSVVSL FYGTCLGVYL SSAATHNSHT GAAASVMYTV VTPMLNPFIY SLRNKHIKGA 310 MKTFFRGKQ
Transmembrane Helices:
TMR7 TMR6 TMR5 TMR4 TMR3 TMR2 TMR1 G T H S L Y V L F T D V M T I V K Q I L E P E A A A G L C I D N L S Q L G A Y N V L F A Q Y M V S T G Y F F Y M V M S N Q T I C M K P V L G F L V V T L S V A V A L V S M F C M T T S S L F L M P T V S L H G G L L I W S F L L F V F C I V L Y M F P N S A C L P G A L V L L G V D V F L V T L S Y I T S F A L I G T L G C L F N D S L N S L L N G R K Y K Y S Y L Q P N V T L L F F L I I G Q A S V I K S D Y A M Y M P T S I T A I S S V F R D I A R H C I A UniProt | I-TASSER | AlphaFold | HORDE | GeneCards | ORDB
| Odorant | EC50 | Adjusted Top | Antagonist? | Aroma Notes |
|---|---|---|---|---|
| rotundone | -7.32 1 | 10 1 | woody, peppery, agarwood, spicy, guaiacwood | |
| (2R,4R)-2,4-diethyl-2,3,4,6,7,8-hexahydro-5H-chromen-5-one | -5.97 1 | - | woody, guaiacwood | |
| pepperwood | -5.17 1 | - | pepper, floral, woody, peppery | |
| 2-ethyl-4-methyl-2,3,4,6,7,8-hexahydro-5H-chromen-5-one | -4.54 1 | - | spicy, peppery, woody, guaiacyl_acetate | |
| isorotundone | -4.47 1 | - | green, woody |
| Prot. | Sim. | Expr. | 2.53 | 3.29 | 3.32 | 3.33 | 3.36 | 3.37 | 3.40 | 3.41 | 4.53 | 4.56 | 4.57 | 4.60 | 45.49 | 45.51 | 45.52 | 45.53 | 5.39 | 5.42 | 5.43 | 5.46 | 5.47 | 6.48 | 6.51 | 6.55 | 6.59 | 7.38 | 7.39 | 7.41 | 7.42 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| OR7A10 | 100 | 73% | F | M | F | L | V | G | N | F | S | N | S | Q | F | E | I | N | M | A | V | L | G | Y | C | Y | S | S | V | Y | T |
| OR7A2 | 92 | F | M | F | V | I | V | S | L | S | N | S | Q | F | E | L | N | M | A | A | L | D | Y | G | Y | S | S | V | Y | T | |
| OR7A5 | 91 | 100% | V | M | F | I | A | G | N | F | S | Y | S | Q | F | E | L | N | I | T | V | L | G | Y | I | Y | S | S | V | Y | T |
| OR7A17 | 90 | 100% | F | M | F | V | G | G | S | L | A | N | S | Q | F | E | L | N | M | A | A | L | A | C | G | Y | S | S | V | Y | T |
| OR7E24 | 87 | 96% | F | M | F | V | A | C | D | M | S | D | S | H | F | D | P | S | I | M | G | F | G | Y | G | Y | S | S | V | Y | T |
| OR8H1 | 86 | 88% | Y | M | F | V | G | A | C | F | S | N | S | N | F | D | T | S | I | L | A | T | L | Y | M | Y | R | S | V | Y | T |
| OR7C2 | 86 | 53% | F | I | F | I | G | C | N | L | S | G | S | E | F | D | P | S | M | V | T | L | G | Y | G | Y | S | S | V | Y | T |
| OR10K1 | 84 | 100% | Y | M | F | L | G | S | S | F | G | V | S | T | F | D | I | S | I | L | G | A | L | Y | A | Y | K | S | V | Y | T |
| OR6P1 | 82 | 65% | Y | L | F | I | A | C | C | V | G | S | S | K | F | D | I | S | D | L | A | M | I | Y | T | Y | R | S | V | Y | T |
| OR5A1 | 81 | 100% | Y | F | F | V | G | L | C | L | G | S | S | Q | F | D | L | P | N | V | V | V | G | F | A | Y | S | S | V | Y | S |
| OR10R2 | 81 | 57% | Y | M | F | L | A | I | C | L | G | A | S | V | F | D | I | S | I | C | G | V | L | Y | A | Y | T | T | V | Y | T |
| OR7G3 | 81 | F | I | V | L | V | G | N | G | S | D | A | H | F | E | L | A | V | V | T | L | G | Y | G | Y | S | S | V | Y | T | |
| OR1C1 | 81 | 100% | F | L | F | V | V | N | S | L | T | H | A | H | F | D | L | N | I | V | G | L | A | Y | A | Y | S | T | I | Y | S |
| OR2D3 | 80 | 100% | F | I | F | L | G | C | C | A | G | V | S | D | F | E | P | P | I | M | G | I | L | Y | G | Y | N | S | V | Y | T |
| OR7G2 | 80 | 80% | L | I | V | L | A | G | N | C | S | N | A | L | F | E | L | A | I | A | A | F | G | Y | G | Y | S | S | V | Y | S |
| OR10AG1 | 80 | 65% | Y | M | F | L | G | G | C | L | T | V | V | E | F | D | I | P | V | V | A | F | I | F | G | Y | K | S | L | Y | T |
| OR7C1 | 80 | 100% | F | I | F | T | G | C | N | L | S | G | S | E | F | D | L | L | I | A | T | L | G | Y | G | Y | S | S | V | Y | T |
| OR1M1 | 80 | 100% | L | M | F | H | G | I | S | V | S | I | S | H | F | D | L | T | I | V | A | V | I | Y | T | Y | S | A | V | Y | T |
| OR2AG1 | 80 | 100% | F | M | A | L | G | G | D | L | A | S | A | Y | L | E | I | P | V | M | G | F | L | Y | A | Y | S | S | V | Y | T |