SMILES:
C1CCCCCCCOC(=O)CCCCCC1
Aroma Description:
animal, fruity, musk, natural, powdery1
| Receptor | log10 EC50 | Adj. Top | Antagonist? | Hypothesized PQ | Associated Perceptual Qualities (PQs) |
|---|---|---|---|---|---|
| OR10Q1 | -4.96 5 | 10 5 | natural, orangeflower, powdery, neroli, animal, musk | ||
| OR4K2 | - | 2.8846 5 | plushy | storax, natural, clove, animal, malty, cortex, musk, foliage, cherry, almond, sharp, powdery | |
| OR5AN1 | - | 2.3881 2 | musky6 |
musk, powdery, animal | |
| OR2J3 | - | 0.4 4 | jagged7 |
warm, candy, cinnamon, currant, hay, foliage | |
| OR7D4 | - | 0.2 3 | animalic3 |
animal | |
| OR4P4 | - | 0.1923 5 | peppery | cloth, laundered, animal, dry | |
| OR5I1 | - | 0 5 |
1.) The Good Scents Company
2.) Ahmed, Lucky et al "Molecular mechanism of activation of human musk receptors OR5AN1 and OR1A1 by (R)-muscone and diverse other musk-smelling compounds." Proceedings of the National Academy of Sciences 115.17 (2018): E3950-E3958. Web. 29 Aug. 2021.
3.) Keller A, Zhuang H, Chi Q, Vosshall LB, Matsunami H. Genetic variation in a human odorant receptor alters odour perception. Nature. 2007 Sep 27;449(7161):468-72. doi: 10.1038/nature06162. Epub 2007 Sep 16. PMID: 17873857.
4.) Ligand Specificity and Evolution of Mammalian Musk Odor Receptors: Effect of Single Receptor Deletion on Odor Detection Narumi Sato-Akuhara, Nao Horio, Aya Kato-Namba, Keiichi Yoshikawa, Yoshihito Niimura, Sayoko Ihara, Mika Shirasu, Kazushige Touhara Journal of Neuroscience 20 April 2016, 36 (16) 4482-4491; DOI: 10.1523/JNEUROSCI.3259-15.2016
5.) Ashti Baghaei, K. (2015). Large scale analysis of olfactory receptors with highly genetically variations in relation with specific anosmia (Doctoral dissertation, Bochum, Ruhr-Universität Bochum, Diss., 2013).
6.) M. Shirasu, K. Yoshikawa, Y. Takai, A. Nakashima, H. Takeuchi, H. Sakano, K. Touhara, Olfactory receptor and neural pathway responsible for highly selective sensing of musk odors, Neuron 81 (2014) 165-178.
7.) PrimaryOdors.org differential experiment.
References for aroma perceptual qualities should not be taken to indicate that the authors of outside studies necessarily assigned aroma notes to the neurons that receive input from any given receptor. Rather, the findings of outside studies often constitute the information on which we base our own perceptual quality assignments.