Olfactory Receptor family 8 subfamily K member 3.
Sequence:
10 20 30 40 50 60 70 80 90 100 MEQHNLTTVN EFILTGITDI AELQAPLFAL FLMIYVISVM GNLGMIVLTK LDSRLQTPMY FFLRHLAFMD LGYSTTVGPK MLVNFVVDKN IISYYFCATQ 110 120 130 140 150 160 170 180 190 200 LAFFLVFIGS ELFILSAMSY DLYVAICNPL LYTVIMSRRV CQVLVAIPYL YCTFISLLVT IKIFTLSFCG YNVISHFYCD SLPLLPLLCS NTHEIELIIL 210 220 230 240 250 260 270 280 290 300 IFAAIDLISS LLIVLLSYLL ILVAILRMNS AGRQKAFSTC GAHLTVVIVF YGTLLFMYVQ PKSSHSFDTD KVASIFYTLV IPMLNPLIYS LRNKDVKYAL 310 320 RRTWNNLCNI FV
Transmembrane Helices:
TMR1 TMR2 TMR3 TMR4 TMR5 TMR6 TMR7 L E A I V F F Y Y S K E H T N Y M F T D F S P A Q N V L T A C I T V L L E I L L T V K D L A F L M K P G F A L Q L S I I L I I G Y F V F I S A M L F V T T V L F F T C Y A A F I V V L T Y I V Y I S Y G L S G I F L Y P I L D I T L H A M P I V M V S D M F F L E I A V L L S S G C T P N L G L N G A L H R A S L I V Q C L V I L S F A K S Y I L V I M L F F Y S M V R R S Y S L Q R G L K T L Y M P T V Y L D L I L L A S N M C I A I A V N R L UniProt | I-TASSER | AlphaFold | HORDE | GeneCards
Odorant | EC50 | Adjusted Top | Antagonist? | Aroma Notes |
---|---|---|---|---|
(+)-menthol | -5.32 1 | 0.1 2 | cooling, mentholic, minty | |
beta-damascone | - | 2.3333 2 | berry, currant, floral, fruity, honey, plum, rose, tobacco | |
quinoline | - | 0.0667 2 | earthy, medicinal, musty, rubbery, tobacco | |
aldehyde C-10 | - | 0 2 | aldehydic, citrus, floral, orange, peel, sweet, waxy | |
aldehyde C-9 | - | 0 2 | aldehydic, fatty, fresh, orange, orris, peel, peely, rose, waxy | |
allyl phenylacetate | - | 0 2 | fruity, honey, rummy | |
amyl hexanoate | - | 0 2 | apple, estery, fatty, fruity, green, pear, pineapple, sweet | |
androstenone | - | 0 2 | animal, musky | |
l-arabinose | - | 0 2 | ||
benzene | - | 0 2 | ||
butyl formate | - | 0 2 | brandy, fruity, plum, rummy | |
butyric acid | - | 0 2 | acetic, buttery, cheesy, fruity, sharp | |
caramel furanone | - | 0 2 | burnt, caramellic, coffee, maple, sugar, sweet | |
(S)-(+)-carvone | - | 0 2 | bready, caraway, minty, spicy | |
citral | - | 0 2 | citrus, lemon, sharp, sweet | |
coffee difuran | - | 0 2 | cabbage, chicken, coffee, meaty, onion, roasted, sulfurous, cocoa, earthy, fungal, mild, mushroom, nutty | |
coumarin | - | 0 2 | coumarinic, hay, sweet, tonka | |
dimethyl disulfide | - | 0 2 | cabbage, onion, sulfurous, vegetable | |
2,4-DNT | - | 0 2 | ||
2-ethyl fenchol | - | 0 2 | camphoraceous, earthy, humus, mushroom, musty, patchouli, potato, rooty, tea | |
ethyl vanillin | - | 0 2 | caramellic, creamy, sweet, vanilla | |
eugenol | - | 0 2 | clove, spicy, sweet, woody | |
eugenyl acetate | - | 0 2 | carnation, clove, floral, fresh, malty, spicy, sweet, woody | |
geranyl acetate | - | 0 2 | floral, green, lavender, rose, waxy | |
helional | - | 0 2 | cyclamen, fresh, green, hay, ozone, watery | |
2-heptanone | - | 0 2 | banana, cheesy, coconut, creamy, fruity, green, herbal, ketonic, spicy, sweet, waxy, woody | |
cis-3-hexen-1-ol | - | 0 2 | foliage, fresh, grassy, green, herbal, oily, vegetable | |
isobutylamine | - | 0 2 | cheesy, fishy | |
d-limonene | - | 0 2 | citrus, fresh, orange, sweet | |
linalool | - | 0 2 | blueberry, bois_de_rose, citrus, floral, green, rose, sweet, woody | |
lyral | - | 0 2 | aquatic, clean, cyclamen, floral, muguet, rhubarb, watery, waxy, woody | |
methyl eugenol | - | 0 2 | carnation, cinnamon, clove, fresh, spicy, sweet, warm | |
methyl furfuryl disulfide | - | 0 2 | alliaceous, coffee, meaty, roasted, sulfurous | |
methyl salicylate | - | 0 2 | minty, wintergreen | |
1-nonanol | - | 0 2 | aldehydic, citrus, clean, dusty, fatty, floral, fresh, oily, orange, rose, sweet, tart, waxy, wet | |
octanethiol | - | 0 2 | sulfurous | |
1-octanol | - | 0 2 | aldehydic, green, mushroom, orange, rose, waxy | |
octyl octanoate | - | 0 2 | coconut, fruity, oily | |
pelargonic acid | - | 0 2 | cheesy, dairy, dirty, waxy | |
pentanol | - | 0 2 | balsamic, fermented, fusel, oily, sweet | |
propanal | - | 0 2 | alcoholic, cocoa, earthy, nutty, whiskey, winey | |
propionic acid | - | 0 2 | acidic, cheesy, pungent, vinegar | |
pyrazine | - | 0 2 | pungent, sweet, corn, roasted, hazelnut, barley | |
terpinyl acetate | - | 0 2 | bergamot, citrus, herbal, lavender, lime |
1.) Dunkel, A.; Steinhaus, M.; Kotthoff, M.; Nowak, B.; Krautwurst, D.; Schieberle, P.; Hofmann, T. Nature’s chemical signatures in human olfaction: A foodborne perspective for future biotechnology. Angew. Chem. Int. Ed. Engl. 2014, 53, 7124–7143.
2.) Adipietro KA, Mainland JD, Matsunami H (2012) Functional Evolution of Mammalian Odorant Receptors. PLoS Genet 8(7): e1002821. doi:10.1371/ journal.pgen.1002821