☰

Olfactory Receptor family 52 subfamily W member 1.

Estimated Expression: 100% of the population.

Expression estimate based on data from Verbeurgt et al (2014).

Sequence:

        10         20         30         40         50         60         70         80         90        100 
MAETLQLNST FLHPNFFILT GFPGLGSAQT WLTLVFGPIY LLALLGNGAL PAVVWIDSTL HQPMFLLLAI LAATDLGLAT SIAPGLLAVL WLGPRSVPYA 

       110        120        130        140        150        160        170        180        190        200 
VCLVQMFFVH ALTAMESGVL LAMACDRAAA IGRPLHYPVL VTKACVGYAA LALALKAVAI VVPFPLLVAK FEHFQAKTIG HTYCAHMAVV ELVVGNTQAT 

       210        220        230        240        250        260        270        280        290        300 
NLYGLALSLA ISGMDILGIT GSYGLIAHAV LQLPTREAHA KAFGTCSSHI CVILAFYIPG LFSYLTHRFG HHTVPKPVHI LLSNIYLLLP PALNPLIYGA 

       310        320 
RTKQIRDRLL ETFTFRKSPL

Transmembrane Helices:

  TMR7     TMR6     TMR5     TMR4     TMR3     TMR2     TMR1   


P K P V       G   A Q T N     V L   P V S R      L W  A S G L  
 I H V   F R H T   L N T   L P F P   V A Y    L V A    W T Q   
N S L L   L Y S   A L G Y   V V I   Q V L C  L L G P  V L T L  
 L Y I   F L G P   L S L   A V A K   F F M    A I S    P G F   
P P L L   I Y F   G S I A   L A L   L A H V  T A L G  L L Y I  
 N L A   A L I V   I D M   A L A A   M A T    L D T    L L A   
Y I L P   C I H   T I G L   Y G V   V G S E  A A L I  A G N G  
   A G   S S C T   Y S G   C A K T   A L L    A L L    A P L   
          G F A   A I L G           D C A M  L F M P  I W V V  
         K A H A   V A H             A A R                 D   
                    L Q L             G I A                    
    

    UniProt | I-TASSER | AlphaFold | HORDE | GeneCards
Odorant EC50 Adjusted Top Antagonist? Aroma Notes
diacetyl - 5.8333 1  buttery, caramellic, creamy, pungent, sweet
butyric acid - 0.5833 1  sharp, acetic, cheesy, buttery, fruity, dairy, creamy
delta-decalactone - 0 1  coconut, creamy, dairy, fatty, fresh, fruity, lactonic, milky, oily, peach, sweet

1.) Geithe, C.; Andersen, G.; Malki, A.; Krautwurst, D. A butter aroma recombinate activates human class-I odorant receptors. J. Agric. Food Chem. 2015, 63, 9410–9420.
Prot.Sim.Expr.2.53 3.29 3.32 3.33 3.36 3.37 3.40 3.41 4.53 4.56 4.57 4.60 45.49 45.51 45.52 45.53 5.39 5.42 5.43 5.46 5.47 6.48 6.51 6.55 6.59 7.38 7.39 7.41 7.42
OR52W1100 100%L M V H T A S G A I V F Y A H M G L S I S Y G Y R S N Y L
OR51T185 76%L M V H S L S S P F L L F Y H P G L Q L N Y L S R A N Y L
OR52A184 88%L M I H Q G S G A L V C Y E H M G V A V A Y A F R S S Y L
OR52E183L M I H T G S A P F V F Y E H M G A I L V Y A F R A N Y V
OR52K282 80%L M L H S I S A A L M L Y E H M G V A I V Y V S R A N Y L
OR52N281 100%L M V H T G S G N L I F Y D H M G V A I G Y A F R A N Y L
OR52N581 92%T M V H T G S G G L M F Y D H M G V A I G Y A F R A N Y L
OR52N481 100%M M T H T G S G G L I F Y D H M G V A I W Y A F R A N Y L
OR52L180 96%L M I H S S S G G L L F Y E H M G M A V I Y G F R A T Y L
OR51F180 34%L M L H T F S G A L I L Y Y H P G D L T T Y M S R A N Y L
OR51I180 100%V M I H S F S G S T L F Y L H P G V I T Y Y I S R S N Y L
OR52E280 42%L M I H T L S A A F V S Y E H M G A I L V Y A F R A N Y V
OR52R180 73%L V I H S S S G G W V F Y E H M G V A V A Y A F R A N Y L
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