Olfactory Receptor family 52 subfamily N member 4.
Sequence:
10 20 30 40 50 60 70 80 90 100 MLTLNKTDLI PASFILNGVP GLEDTQLWIS FPFCSMYVVA MVGNCGLLYL IHYEDALHKP MYYFLAMLSF TDLVMCSSTI PKALCIFWFH LKDIGFDECL 110 120 130 140 150 160 170 180 190 200 VQMFFTHTFT GMESGVLMLM ALDRYVAICY PLRYSTILTN PVIAKVGTAT FLRGVLLIIP FTFLTKLLPY CRGNILPHTY CDHMSVAKLS CGNVKVNAIY 210 220 230 240 250 260 270 280 290 300 GLMVALLIWG FDILCITNSY TMILRAVVSL SSADARQKAF NTCTAHICAI VFSYTPAFFS FFSHRFGEHI IPPSCHIIVA NIYLLLPPTM NPIVYGVKTK 310 320 330 QIRDCVIRIL SGSKDTKSYS M
Transmembrane Helices:
TMR1 TMR2 TMR3 TMR4 TMR5 TMR6 TMR7 D E L G I C L E D F G L V K V N S C S P P L Q T A K P I V L C F T F P I A N F F S F I I H F S I W T S S F F M Q I I L M L G Y F A P I N A V C F P C M V L T H T L V G R L A V T Y S F L L Y V Y M S D T F M G T F L F T G W I L V I A T P P L M A V S L M A G S E A T G V I D F C I H A P N M C N G V L F Y L M L V K A I T I C L T C T G Y V I L L G Y M P K L A M V P N T Y S N N F A K K V H I L Y V Y R D L I M T Q R A C I A V A R D A S S Y S V UniProt | I-TASSER | AlphaFold | HORDE | GeneCards | ORDB
| Odorant | EC50 | Adjusted Top | Antagonist? | Aroma Notes |
|---|---|---|---|---|
| hexanal | - | 0.5 1 | aldehydic, fatty, fresh, fruity, grass, green, leafy, sweaty | |
| butyric acid | - | 0 2 | sharp, acetic, cheesy, buttery, fruity, dairy, creamy | |
| delta-decalactone | - | 0 2 | coconut, creamy, dairy, fatty, fresh, fruity, lactonic, milky, oily, peach, sweet | |
| diacetyl | - | 0 2 | buttery, caramellic, creamy, pungent, sweet |
1.) Ojiro I, Katsuyama H, Kaneko R, Ogasawara S, Murata T, Terada Y, et al. (2024) Enhancement of transcription efficiency by TAR-Tat system increases the functional expression of human olfactory receptors. PLoS ONE 19(6): e0306029. https://doi.org/10.1371/journal.pone.0306029
2.) Geithe, C.; Andersen, G.; Malki, A.; Krautwurst, D. A butter aroma recombinate activates human class-I odorant receptors. J. Agric. Food Chem. 2015, 63, 9410–9420.