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SMILES:
CCCCC(=O)[O-]

Aroma Description:
acidic, cheesy, fruity, milky, sharp, sour, tobacco1

Receptor log10 EC50 Adj. Top Antagonist? Correlated Perceptual Qualities
OR51E1 -2.82 2, -4.74 5 -  cheesy, sweaty, sour, acidic
OR51I2 -4.07 7 7.8 7  cheesy, sour, sweaty, sharp, acidic
OR52L1 -3.05 7 1.6 7  milky, dairy, lactonic, peach, coconut, creamy
OR51E2 - 0.4 6  vinegar, sour, sharp, radish
OR10J5 - 0 3   
OR1A1 - 0 3   
OR2C1 - 0 3   
OR2J2 - 0 3   
OR2W1 - 0 3   
OR51L1 - 0 3   
OR5P3 - 0 3   
OR5A1 - 0 4   
OR5A2 - 0 4   
OR5AN1 - 0 4   
 

SMILES:
CCCCC(=O)[O-]

Aroma Description:
acidic, cheesy, fruity, milky, sharp, sour, tobacco

Receptor Dock Score Affinity A100 Correlated Perceptual Qualities
OR51E1 8.9739 17.7264 51.6819 cheesy, sweaty, sour, acidic
OR51E2 2.3686 18.7005 47.9003 vinegar, sour, sharp, radish

Dock Score: This is a measure of whether the algorithm thinks the odorant is an agonist of the receptor.
Affinity: The binding affinity, in kJ/mol, of the ligand docked in the active or inactive model, whichever is greater.
A100: A measure of the degree of activation of the receptor. See Ibrahim et al (2019).

1.) The Good Scents Company

2.) YOSHIFUMI FUJITA, TOMOKO TAKAHASHI, AKIKO SUZUKI, KAYO KAWASHIMA, FUTOSHI NARA & RYUTA KOISHI (2007) Deorphanization of Dresden G Protein-Coupled Receptor for an Odorant Receptor, Journal of Receptors and Signal Transduction, 27:4, 323-334, DOI: 10.1080/10799890701534180

3.) Saito H, Chi Q, Zhuang H, Matsunami H, Mainland JD. Odor coding by a Mammalian receptor repertoire. Sci Signal. 2009 Mar 3;2(60):ra9. doi: 10.1126/scisignal.2000016. PMID: 19261596; PMCID: PMC2774247.

4.) Keiichi Yoshikawa, Jun Deguchi, Hu Jieying et al. Diverse yet selective tuning of an odorant receptor for sensing four classes of musk compounds, 03 August 2022, PREPRINT (Version 1) available at Research Square [https://doi.org/10.21203/rs.3.rs-1916850/v1]

5.) Halperin Kuhns, V. L., Sanchez, J., Sarver, D. C., Khalil, Z., Rajkumar, P., Marr, K. A., & Pluznick, J. L. (2019). Characterizing novel olfactory receptors expressed in the murine renal cortex. American Journal of Physiology-Renal Physiology, 317(1), F172-F186.

6.) Christian B. Billesbølle, Claire A. de March, Wijnand J. C. van der Velden, Ning Ma, Jeevan Tewari, Claudia Llinas del Torrent, Linus Li, Bryan Faust, Nagarajan Vaidehi, Hiroaki Matsunami, Aashish Manglik. Structural basis of odorant recognition by a human odorant receptor. bioRxiv 2022.12.20.520951; doi: https://doi.org/10.1101/2022.12.20.520951

7.) Chatelain Pierre, Veithen Alex, Olfactory Receptors involved in the perception of sweat carboxylic acids and the use thereof. WO 2014/191047