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Olfactory Receptor family 51 subfamily V member 1.

Estimated Expression: 69% of the population.

Expression estimate based on data from Verbeurgt et al (2014).

Sequence:

        10         20         30         40         50         60         70         80         90        100 
MFLSSRMITS VSPSTSTNSS FLLTGFSGME QQYPWLSIPF SSIYAMVLLG NCMVLHVIWT EPSLHQPMFY FLSMLALTDL CMGLSTVYTV LGILWGIIRE 

       110        120        130        140        150        160        170        180        190        200 
ISLDSCIAQS YFIHGLSFME SSVLLTMAFD RYIAICNPLR YSSILTNSRI IKIGLTIIGR SFFFITPPII CLKFFNYCHF HILSHSFCLH QDLLRLACSD 

       210        220        230        240        250        260        270        280        290        300 
IRFNSYYALM LVICILLLDA ILILFSYILI LKSVLAVASQ EERHKLFQTC ISHICAVLVF YIPIISLTMV HRFGKHLSPV AHVLIGNIYI LFPPLMNPII 

       310        320        330 
YSVKTQQIHT RMLRLFSLKR Y

Transmembrane Helices:

  TMR7     TMR6     TMR5     TMR4     TMR3     TMR2     TMR1   


A V P S       G   F R I D     L C   S I E R      G W  Q Q E M  
 L V H   F R H V   Y S N   I I P P   S D L    L I G    W P Y   
I N G I   M T L   M L A Y   T I F   Q A I C  L V T Y  P I S L  
 L I Y   S I I P   I V L   F F S R   F Y S    V T S    S S F   
L P P F   I Y F   L L I C   G I I   L G H I  L G M C  M A Y I  
 P N M   V L V A   A D L   T L G I   M F S    L D T    L L V   
S Y I I   C I H   L I L I   K I I   V S S E  L A L M  M C N G  
     V   S I C T   Y S F   R S N T   T L L    S L F    H L V   
          Q F L   L I L I           D F A M  Y F M P  T W I V  
         K H R E   V S K             I Y R                 E   
                    V A L             C I A                    
    

    UniProt | I-TASSER | AlphaFold | HORDE | GeneCards
Odorant EC50 Adjusted Top Antagonist? Aroma Notes
butyric acid - 0 1  sharp, acetic, cheesy, buttery, fruity, dairy, creamy
delta-decalactone - 0 1  coconut, creamy, dairy, fatty, fresh, fruity, lactonic, milky, oily, peach, sweet
diacetyl - 0 1  buttery, caramellic, creamy, pungent, sweet

1.) Geithe, C.; Andersen, G.; Malki, A.; Krautwurst, D. A butter aroma recombinate activates human class-I odorant receptors. J. Agric. Food Chem. 2015, 63, 9410–9420.
Prot.Sim.Expr.2.53 3.29 3.32 3.33 3.36 3.37 3.40 3.41 4.53 4.56 4.57 4.60 45.49 45.51 45.52 45.53 5.39 5.42 5.43 5.46 5.47 6.48 6.51 6.55 6.59 7.38 7.39 7.41 7.42
OR51V1100 69%M S I H S F S S S F I P F L H Q A L V I L Y I T R G N Y I
OR51A289 84%L E I H S V S S S L V F Y L H Q G G A L M Y I A R A N L L
OR51A489 84%L E I H S V S S S L V F Y L H Q G G A L M Y I A R A N L L
OR51Q188 100%L F L H S F S S C A V S Y L H Q G L A I I Y M S R A N Y L
OR51E287 96%L M I H S A S T G F F L Y V H Q G A I V M Y L S R G D Y L
OR51E187 100%I M I H S G S T G L M L Y L H Q G V I A I Y F S R A N Y L
OR51G286 92%L L I H S F S S S L I L Y L H Q G V I T V Y M S R G F Y L
OR51L186 88%M L I H T F S S S V V T F L H Q G V V T L F V S R A D Y L
OR51D185 65%L M I H S A S A G F F L F L H Q G I I V M Y L S R A N Y L
OR51M183 100%L M I H S F S S G A T I F L H Q G V V T V F M S R A N Y L
OR51A782 84%L E I H T V S S S L V F Y L H Q G I A T M Y I A H A D F L
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