Olfactory Receptor family 51 subfamily D member 1.
Sequence:
10 20 30 40 50 60 70 80 90 100 MQKPQLLVPI IATSNGNLVH AAYFLLVGIP GLGPTIHFWL AFPLCFMYAL ATLGNLTIVL IIRVERRLHE PMYLFLAMLS TIDLVLSSIT MPKMASLFLM 110 120 130 140 150 160 170 180 190 200 GIQEIEFNIC LAQMFLIHAL SAVESAVLLA MAFDRFVAIC HPLRHASVLT GCTVAKIGLS ALTRGFVFFF PLPFILKWLS YCQTHTVTHS FCLHQDIMKL 210 220 230 240 250 260 270 280 290 300 SCTDTRVNVV YGLFIILSVM GVDSLFIGFS YILILWAVLE LSSRRAALKA FNTCISHLCA VLVFYVPLIG LSVVHRLGGP TSLLHVVMAN TYLLLPPVVN 310 320 330 PLVYGAKTKE ICSRVLCMFS QGGK
Transmembrane Helices:
TMR1 TMR2 TMR3 TMR4 TMR5 TMR6 TMR7 I T P G L F I N F E I V R T D V L L S T W F H L S A A L C F P L P V V N V S L G V V H P F A L M K P M L F M Q F F F F L G Y I L P T N A M F C L T I S A H I V F G R L I I V Y F V L L Y L A Y M S L V L V A S L T L A G M V S L V A V P P L L T A D I T A S E S L G I S D V C L H S P N V T L N G S L M A A L L V K A V G I F L I C T G Y V L L V I L F L F A M T C G T Y S F N F A K A R I I Y M P E V F R D L I L I L A A C I A V A W R R S S H E L UniProt | I-TASSER | AlphaFold | HORDE | GeneCards | ORDB
| Odorant | EC50 | Adjusted Top | Antagonist? | Aroma Notes |
|---|---|---|---|---|
| butyric acid | -4.13 1 | 0.1821 1 | sharp, acetic, cheesy, buttery, fruity, dairy, creamy | |
| delta-decalactone | - | 3.3333 2 | coconut, creamy, dairy, fatty, fresh, fruity, lactonic, milky, oily, peach, sweet | |
| diacetyl | - | 0 2 | buttery, caramellic, creamy, pungent, sweet |
1.) Mainland JD, Li YR, Zhou T, Liu WL, Matsunami H. Human olfactory receptor responses to odorants. Sci Data. 2015 Feb 3;2:150002. doi: 10.1038/sdata.2015.2. PMID: 25977809; PMCID: PMC4412152.
2.) Geithe, C.; Andersen, G.; Malki, A.; Krautwurst, D. A butter aroma recombinate activates human class-I odorant receptors. J. Agric. Food Chem. 2015, 63, 9410–9420.